- Pharmaceutical and Antibiotic Environmental Impacts
- Effects and risks of endocrine disrupting chemicals
- Forensic Toxicology and Drug Analysis
- Microplastics and Plastic Pollution
- Cannabis and Cannabinoid Research
- Metabolomics and Mass Spectrometry Studies
- Toxic Organic Pollutants Impact
- Analytical chemistry methods development
- Biosensors and Analytical Detection
- Water Quality Monitoring Technologies
- Youth, Drugs, and Violence
- Recycling and Waste Management Techniques
- COVID-19 Clinical Research Studies
- Polymer Science and PVC
- Analytical Chemistry and Chromatography
- Carcinogens and Genotoxicity Assessment
- Pharmacogenetics and Drug Metabolism
- Child Nutrition and Feeding Issues
- Air Quality Monitoring and Forecasting
- Metabolism and Genetic Disorders
- Alcohol Consumption and Health Effects
- SARS-CoV-2 detection and testing
Universidade de Santiago de Compostela
2019-2024
The COVID-19 pandemic spread rapidly worldwide in the year 2020, which was initially restrained by drastic mobility restrictions. In this work, we investigated use of illicit drugs (amphetamine, methamphetamine, ecstasy, cocaine and cannabis), licit substances abuse (alcohol tobacco) during earlier months (March–July 2020) restrictions four Spanish (Bilbao its metropolitan area, Vitoria-Gasteiz, Castellón Santiago de Compostela) two Portuguese (Porto Vila do Conde) locations wastewater-based...
Wastewater-based epidemiology (WBE) has become an invaluable tool for tracking the evolution of use or exposure of/to numerous substances. Bisphenols, commonly utilized in manufacturing plastic goods, have been categorized as endocrine disrupting chemicals, underscoring critical need real-time data on their local-level to safeguard public health. In this study, we developed a novel analytical method and WBE framework assessment population-level bisphenol A (BPA) its most prominent...
This review describes a wide variety of analytical approaches for the assessment human exposure to organic chemicals associated with plastic additives, focusing on works published in last decade plasticisers, bisphenols, flame retardants and antioxidants. Physiologically based extraction tests serve as preliminary in-vitro assays determine bioaccessibility these compounds from micro/nanoplastics body fluids gastrointestinal tract, skin, or lung. Whenever plastic-laden become bioavailable,...
Abstract Bisphenols are widely used as monomers and additives in plastic production. Thus, bisphenol A (BPA) its most prominent substitutes have been detected many environmental human samples. This study proposes an online solid-phase extraction analytical methodology coupled to liquid chromatography with tandem mass spectrometry for the determination of six bisphenols (BPA F (BPF), S (BPS), AF (BPAF), B (BPB), E (BPE)) urine samples efficient automated methodology. The method was developed...
Amphetamine (AMP), methamphetamine (MAMP) and 3,4-methylenedioxymethamphetamine (MDMA) occur in wastewater not only as a result of illicit consumption, but also, some cases, from prescription drug use or by direct disposal into the sewage system. Enantiomeric profiling these chiral drugs could give more insight origin their occurrence. In this manuscript, new analytical methodology for enantiomeric analysis amphetamine-like substances has been developed. The method consists solid-phase...
Tris (1-chloro-2-propyl) phosphate (TCIPP) is one of the major organophosphate flame retardants present in indoor and outdoor environment. Knowledge biotransformation pathways important to elucidate potential bioavailability toxicity TCIPP identify relevant biomarkers. This study aimed metabolites through vitro human metabolism assays finally confirm these findings urine samples from an occupationally exposed population propose new biomarkers accurately monitor exposure TCIPP. was incubated...
Abstract This work provides a new analytical method for the determination of cocaine, its metabolites benzoylecgonine and cocaethylene, pyrolytic products anhydroecgonine methyl ester, pharmaceutical levamisole in wastewater. Samples were solid‐phase extracted extracts analyzed by liquid chromatography–tandem mass spectrometry using, first time illicit drug field, stationary phase that combines reversed‐phase weak cation‐exchange functionalities. The overall performance was satisfactory,...
El uso de guanidinas diarílicas como aditivos en productos químicos relacionados con polímeros está aumento, lo que incrementa el riesgo exposición humana no intencionada a estos compuestos. descubrimiento los efectos peligrosos asociados la 1,3-difenilguanidina (DPG) y 1,3-di-o-tolilguanidina (DTG) ha impulsado necesidad estudios biomonitorización para detectar estas sustancias. Sin embargo, hay información limitada sobre metabolismo Para abordar esta laguna, este estudio investiga...