- Solidification and crystal growth phenomena
- Aluminum Alloy Microstructure Properties
- Metal-Organic Frameworks: Synthesis and Applications
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- High Temperature Alloys and Creep
- Magnetism in coordination complexes
- Fluid Dynamics and Thin Films
- Diabetes Management and Research
- Fusion materials and technologies
- Retinoids in leukemia and cellular processes
- Bone health and osteoporosis research
- Nuclear Physics and Applications
- Gestational Diabetes Research and Management
- Polymer composites and self-healing
- Peptidase Inhibition and Analysis
- Risk and Safety Analysis
- Advanced Graph Neural Networks
- Risk Perception and Management
- Thermography and Photoacoustic Techniques
- Text and Document Classification Technologies
- Advanced Sensor and Energy Harvesting Materials
- Protein Degradation and Inhibitors
- Bone Metabolism and Diseases
- Metal complexes synthesis and properties
- Lanthanide and Transition Metal Complexes
Shanghai Institute of Materia Medica
2024
Chinese Academy of Sciences
2006-2024
Fudan University
2024
University of Science and Technology of China
2017-2023
Zhejiang Gongshang University
2022
Hefei Institutes of Physical Science
2019-2021
Anhui Provincial Hospital
2018-2020
Ningbo Institute of Industrial Technology
2020
Institute of Solid State Physics
2017
Material Physics Center
2017
Proteolysis-targeting chimera (PROTAC) is a powerful technology that can effectively trigger the degradation of target proteins. The intricate interplay among various factors leads to heterogeneous drug response, bringing about significant challenges in comprehending mechanisms. Our study applied data-independent acquisition-based mass spectrometry multidimensional proteome profiling PROTAC (DIA-MPP) uncover efficacy and sensitivity compound. We profiled signal transducer activator...
[reaction: see text] Schiff-base amino alcohols 7a,b derived from L-phenylglycine through three simple steps are found to be highly effective for the enantioselective addition of phenylacetylene aromatic ketones. When loading 7b was 1 mol %, an ee value up 95% obtained. However, when lowered 0.1 a high 85% still achieved. A practical solution synthesize optically active tertiary propargylic described.
Concentrated and long-term stable Ag nanowire ink is formulated to coat transparent conductive films with superior comprehensive performance after simple cleaning.
Significance Despite great efforts to pursue a safe nuclear energy system during the first era, which was dominated by developed countries, severe accidents still occurred. Today, development has entered an unexpected second is driven developing countries. This may give rise risk. Nuclear power plants are complex sociotechnical systems, and their safety never been fully defined. We argue that social aspects, rather than just technical measures, must be involved ensure safety. In this paper,...
The purposes of this study were to evaluate the expression retinol-binding protein 4 (RBP4) in diabetic rats with atherosclerosis and investigate role vitamin D intervention. Male Wistar randomly divided into groups, including control group (NC), (DM1), untreated (DM2), D-treated (DM3). levels serum adipose RBP4, fasting insulin (FINS), plasma glucose (FPG), total cholesterol (TC), high-density lipoprotein (HDL-c), triglycerides (TG), low-density (LDL-c), 25-hydroxyvitamin [25(OH)D],...
A one-dimensional iron(II) coordination polymer, [Fe(3)(hpdc)(2)(H(2)O)(6)]·2H(2)O (H(3)hpdc = 2-hydroxypyrimidine-4,6-dicarboxylic acid) has been synthesized and characterized. The compound exhibits field-induced two-step magnetic phase transitions a coexistence of spin-canting metamagnetism, undergoes structural transformation from single-crystalline to amorphous state upon dehydration, accompanied by significantly enhanced spontaneous magnetization critical temperature.
Osteoporosis is a systemic skeletal disorder characterizedby reduced bone mass, deteriorated structure. Various studies have tried to evaluate the association between lipid level and osteoporosis, but results were proved be controversial. The objectives of this study are assess correlation BMD serum levels, determine independent variables associated with osteoporosis osteopenia in men postmenopausal women type 2 diabetes (T2D).All participants carried out biochemical analysis blood profile...
Abstract In this paper, phase field model is employed to simulate the process of femtosecond laser which irradiates on silicon surface. The numerical mainly used study micro/nano evolution and atomic diffusion motion system. Meanwhile, Semi-Implicit Fourier spectral method Backwards Differentiation Formula are applied for high efficiency stability. Further, rules surface bumps controlled by different thermal conductivities systematically revealed. Our work provides a new prospect fabricating...