Margaret L. Tyer

ORCID: 0000-0002-8128-5655
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About
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  • Prion Diseases and Protein Misfolding

Colorado State University
2020

CWD is an emergent prion disease that now affects cervid species on three continents. efficiently spread in wild and captive populations, likely through both direct animal contact environmental contamination. Here, by longitudinally assaying feces of CWD-exposed white-tailed deer RT-QuIC, we demonstrate fecal shedding seeding activity months before onset clinical symptoms continuing throughout the course. We also examine impact simulated conditions such as repeated freeze-thaw cycles...

10.1371/journal.pone.0227094 article EN cc-by PLoS ONE 2020-03-03
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