A5077859938- Plant Pathogens and Fungal Diseases
- Nail Diseases and Treatments
- Fungal Infections and Studies
- Infectious Diseases and Mycology
- Antifungal resistance and susceptibility
- Sinusitis and nasal conditions
- Coccidia and coccidiosis research
- Reproductive System and Pregnancy
- Echinoderm biology and ecology
- Corneal surgery and disorders
- Ocular Surface and Contact Lens
- Silymarin and Mushroom Poisoning
- Mycobacterium research and diagnosis
- Drug-Induced Hepatotoxicity and Protection
- Fungal Plant Pathogen Control
- Cervical Cancer and HPV Research
- Herbal Medicine Research Studies
- Mycorrhizal Fungi and Plant Interactions
- Reproductive tract infections research
- Lichen and fungal ecology
- Seaweed-derived Bioactive Compounds
- Ocular Infections and Treatments
Bushehr University of Medical Sciences
2024-2025
Shiraz University of Medical Sciences
2021-2022
Ahvaz Jundishapur University of Medical Sciences
2017-2021
Trichophyton mentagrophytes and T. interdigitale are important causative agents of superficial mycoses, demonstrating emergent antifungal drug resistance. We studied the susceptibility profiles in Iranian isolates these two species.A total 96 45 were subjected to molecular typing by ribosomal ITS region. Antifungal for terbinafine, griseofulvin, clotrimazole, efinaconazole, luliconazole, amorolfine ciclopirox obtained CLSI broth microdilution method. The squalene epoxidase (SQLE) gene was...
Silymarin is a polyphenolic flavonoid extracted from milk thistle. It has potent immunomodulatory effects and can inhibit the replication of influenza A virus (IAV). The present study aimed to determine inflammatory anti‐inflammatory cytokine secretion patterns in mice before after silibinin treatment. For this, bronchoalveolar lavage (BAL) fluids were collected thoracic cavity 5 days intervention, viral quantification was performed using TaqMan Real‐time PCR. Enzyme‐linked immunosorbent...
Sea cucumber has antiviral activities against various viruses including herpes simplex virus type 1 (HSV-1). The purpose of the current study was to determine chemical profile and inhibitory effects tegument ethanolic extract Holothuria parva on HSV-1 infection elucidate mechanism action this marine invertebrate. Cytotoxic activity Vero cell line determined using methyl thiazolyl tetrazolium (MTT) method. different components in H. were by GC-MS analysis. To assess extract, MTT 50% tissue...
Pathogens from the Trichophyton benhamiae complex are one of most important causes animal mycoses with significant zoonotic potential. In light recently revised taxonomy this complex, we retrospectively identified 38 isolates that could not be resolved into any existing species. These strains were isolated Iranian and Czech patients during molecular epidemiological surveys on dermatophytosis predominantly associated highly inflammatory tinea corporis cases, suggesting possible etiology....
Fungal rhinosinusitis (FRS) encompasses a various spectrum of diseases. Histopathology is the "reference method" for diagnosing FRS, but it cannot determine genus and species. Moreover, in more than 50% histopathologically proven cases, culture elicited no reliable results. This study was an attempt to evaluate diagnostic efficiency semi-nested polymerase chain reaction (PCR) from formalin-fixed paraffin-embedded (FFPE) functional endoscopic sinus surgery (FESS) FRS patients.One hundred ten...
Summary Background Dermatophytes are a group of keratinophilic fungi medical importance. Despite relatively long history molecular taxonomic studies, there is still need for information on genetic polymorphism in wider variety genomic loci. Objectives Our goal was to study partial DNA topoisomerase 2 gene ( TOP2 ) dermatophytes. Methods We performed sequencing 26 dermatophyte species along with ribosomal internal transcribed spacer (ITS) sequencing. Results The number polymorphic sites data...
Species from the Trichophyton benhamiae complex are mostly zoophilic dermatophytes which cause inflammatory dermatophytosis in animals and humans worldwide.This study was purposed to (a) identify 169 reference clinical dermatophyte strains T species by molecular method adhering newest taxonomy (b) evaluate vitro antifungal susceptibility profile of these against eight common new agents that may be used for treatment dermatophytosis.All isolates, mainly originated Europe but also Iran, Japan...
Fungal species are responsible for 40%-50% of all microbial keratitis cases. Due to the low amount extracted DNA in ocular Formalin-fixed Paraffin-embedded (FFPE) samples, selecting a reliable molecular method is substantial issue this field.Sixty-six samples were collected via penetrating keratoplasty (PK) technique. Histopathology assays performed using hematoxylin-eosin (H&E) and periodic acid Schiff (PAS) staining methods. The ITS1/ITS4 ITS1/ITS2 primer pairs used semi-nested polymerase...
Background: Recurrent vulvovaginal candidiasis (RVVC) is a widespread opportunistic gynecological condition resulting from infections by Candida albicans and non-C. (NAC) species. Transforming growth factor-beta (TGF-β), significant cytokine involved in cell-mediated immunity (CMI), plays crucial role vaginal infections. Objectives: The current study was conducted to evaluate the differences TGF-β gene expression between patients with RVVC healthy individuals using real-time polymerase chain...
Members of the Nannizzia gypsea complex are globally most common geophilic dermatophytes which cause infection in animals and human. Although susceptibility patterns anthropophilic or zoophilic dermatophyte species to antifungal agents well documented, effectiveness such drugs against have rarely been explored.This study was aimed evaluate vitro activity new antifungals a set environmental clinical isolates.108 soil isolates from two genera (N. fulva n = 59; N. 43) Arthroderma (A....
Abstract Background Fungal rhinosinusitis (FRS) encompasses a various spectrum of disease, which vary in clinical presentation, histologic features, and biological significance. FRS is commonly classified two categories, i.e., invasive non-invasive infection. Histopathology the “gold standard” diagnostic method, but it not able to determine genus species. Almost more than 50% histopathologically proven cases, culture elicited no reliable results. This study was an attempt evaluate efficiency...