- Coronary Interventions and Diagnostics
- Aortic aneurysm repair treatments
- Cerebrovascular and Carotid Artery Diseases
- Aortic Disease and Treatment Approaches
- Lipoproteins and Cardiovascular Health
- Cardiac Imaging and Diagnostics
- Sexual function and dysfunction studies
- Healthcare Regulation
- Cardiac Valve Diseases and Treatments
- Nitric Oxide and Endothelin Effects
- Academic Research in Diverse Fields
- Atherosclerosis and Cardiovascular Diseases
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Infective Endocarditis Diagnosis and Management
- Cardiac tumors and thrombi
- Venous Thromboembolism Diagnosis and Management
- Pericarditis and Cardiac Tamponade
- Cardiovascular Health and Disease Prevention
- Hormonal and reproductive studies
- Cardiovascular Function and Risk Factors
- Peripheral Artery Disease Management
- Healthcare during COVID-19 Pandemic
- Central Venous Catheters and Hemodialysis
- Public Health in Brazil
- Ultrasound and Hyperthermia Applications
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
2025
Universidade Federal do Rio Grande do Sul
1998-2020
Hospital de Clínicas de Porto Alegre
1993-2020
Universidade Luterana do Brasil
2006-2012
Hospital Mãe de Deus
2011
Universidade Federal do Rio Grande
1998
University of Toronto
1997
Mount Sinai Hospital
1997
Objectives To test the local delivery of sirolimus nanoparticles following percutaneous transluminal coronary angioplasty (PTCA) to treat in‐stent restenosis (ISR) in a swine model. Background Coronary bare‐metal stent (BMS) implantation reduces major adverse cardiac events when compared with PTCA; however, ISR rates remain high. Methods Eighteen underwent BMS deployment guided by intravascular ultrasound (IVUS). Of these, 16 developed (1 stent/swine) and noncompliant balloon (PTCA‐NC). The...
Statins have anti-inflammatory and antiproliferative properties irrespective of their cholesterol-lowering effects. The aim the present study was to evaluate a simvastatin-eluting stent (SimvES) in treatment de novo coronary lesions.Forty-two patients with artery lesions were assigned SimvES, bare-metal (BMS) or everolimus-eluting (EES) implantation followed by intravascular ultrasound (IVUS) for neointimal quantitative analysis. Six months later, angiography (QCA) IVUS repeated. QCA showed...
Abstract Pseudoaneurysm of the ascending aorta is an uncommon pathology and a challenge in high‐risk patients who undergo conventional surgery because high operative morbidity mortality. Endovascular exclusion aortic pseudoaneurysm using endoprosthesis less invasive approach, but few such cases have been reported. Moreover, use this approach poses unique therapeutic challenges there no specific for repair, particularly to treat with previous coronary artery bypass graft (CABG). We describe...
Lipoprotein lipase is the rate-limiting enzyme in lipolysis of plasma triglyceride-rich lipoproteins. We studied six variants (T-93G, D9N, N291S, PvuII, HindIII and S447X) lipoprotein (LPL) gene 309 nondiabetic patients with angiographically assessed coronary artery disease 197 controls a southern Brazilian population European descent. The H-allele was associated lower triglycerides (p < 0.01) higher high-density cholesterol = 0.03) levels, S447X mutation triglyceride levels males, but not...
O rim em ferradura é uma anomalia congênita rara que pode causar várias dificuldades técnicas durante a correção convencional de aneurisma aorta abdominal. Relatamos o caso paciente 68 anos com ferradura, abdominal sintomático e disfunção renal leve. A foi submetida endovascular, sendo utilizada endoprótese bifurcada. pós-operatório livre complicações. diagnóstico técnica endovascular são discutidos, assim como literatura revisada.
Endovascular treatment of ascending aorta pseudoaneurysms with coronary stents implantation at the same procedure was feasible, although longer followup is necessary.
To verify the association of serum markers myocardial injury, such as troponin I, creatinine kinase, and kinase isoenzyme MB, inflammatory markers, tumor necrosis factor alpha (TNF-alpha), C-reactive protein, erythrocyte sedimentation rate in perioperative period cardiac surgery, with occurrence possible postpericardiotomy syndrome.This was a cohort study 96 patients undergoing surgery assessed at following 4 different time periods: day before (D0); 3rd postoperative (D3); between 7th 10th...
OBJETIVO: O estudo visa a apresentar os resultados curto e médio prazo do tratamento endovascular dos aneurismas de aorta abdominal (AAA). Trata-se uma experiência inicial com equipe multidisciplinar. MÉTODO: No período entre julho 2003 outubro 2005, 42 pacientes foram submetidos doenças da aorta, sendo 25 por A idade média foi 74 ± 10,2 anos 92% eram sexo masculino. Os procedimentos realizados multidisciplinar, no Hospital Clínicas Porto Alegre Luterano (ULBRA). Vinte quatro à colocação...
INTRODUÇÃO: Há múltiplos modelos experimentais em animais, entretanto o modelo suíno é que apresenta características anatômicas e funcionais mais próximas às humanas. Assim sendo, este trabalho foi realizado com objetivo de desenvolver implementar um protocolo experimental indução hiperproliferação neointimal suínos, visando à criação técnicas lesão vascular simulando a reestenose. MÉTODO: De agosto 2006 março 2009, 69 suínos jovens da raça Large White foram submetidos cinecoronariografia...
Situs inversus totalis is a rare congenital anomaly. We report case of 78-year-old woman with this condition and ischemic coronary artery disease who underwent myocardial revascularization. The cardiac catheterism showed severe proximal stenosis aneurysms in the anterior interventricular branch, diagonal artery, right artery. procedure was done surgeon positioned left hand side patient, internal thoracic anastomosed to two more vein grafts. Very few cases have been reported world third...
INTRODUÇÃO: A substituição cirúrgica da valva aórtica é o tratamento de eleição para pacientes com estenose acentuada. Entretanto, risco cirúrgico aumenta expressivamente avançar idade e a associação comorbidades. Recentemente, iniciou-se experiência implante por cateter biopróteses aórticas no Brasil. Justifica-se, portanto, criação um registro nacional conhecimento dos resultados desse tipo procedimento em nosso meio. Descrevemos racional desenho do Registro Brasileiro Implante Bioprótese...
Coronary restenosis is a poorly understood phenomenon that remains challenge even in the drug-eluting stent era. This study aimed to identify genes involved synthesis of structural and functional proteins smooth muscle cells with increased expression human atheromatous plaques associated neointimal hyperplasia after bare-metal implantation. Atheromatous were obtained by directional atherectomy prior stenting. A gene analysis was performed using Affymetrix GeneChip system. The patients...
Transluminal coronary angioplasty is a routine therapeutic intervention in heart disease. Despite the high rate of primary success, restenosis continues to be its major limitation. Porcine models have been considered most adequate experimental for studying restenosis. One limitation porcine need radiological guidance and expenses involved. The objective present study was adapt an model carotid artery that does not require equipment. Eight animals were used develop technique balloon injury...
Many clinical and epidemiological studies have demonstrated the relationship between serum ferritin ischemic heart disease. In present study we evaluated coronary disease (CHD) levels in patients submitted to arteriography. We 307 (210 (68.7%) males; median age: 60 years) who were angiography, measurement of identification events Serum is reported as quartiles. Ninety-six (31.27%) had normal angiography (group 1) 211 (68.73%) 2). Of with CHD, 61 (28.9%) higher than 194 ng/ml (4th quartile),...