A5044775163- Microbial Natural Products and Biosynthesis
- Mycotoxins in Agriculture and Food
- Plant Pathogens and Fungal Diseases
- RNA and protein synthesis mechanisms
- Bioinformatics and Genomic Networks
- Venomous Animal Envenomation and Studies
- RNA Research and Splicing
- Microbial Metabolic Engineering and Bioproduction
- Fungal and yeast genetics research
- Antimicrobial Peptides and Activities
- Enzyme Catalysis and Immobilization
- Biochemical and Structural Characterization
- interferon and immune responses
Universidad Nacional Autónoma de México
2017-2018
Protein subcellular localization is fundamental to the establishment of body axis, cell migration, synaptic plasticity, and a vast range other biological processes. occurs through three mechanisms: protein transport, mRNA localization, local translation. However, relative contribution each process neuronal polarity remains unknown. Using neurons differentiated from mouse embryonic stem cells, we analyze RNA expression translation rates in isolated bodies neurites genome-wide. We quantify...
This communication reports a further examination of venom gland transcripts and composition the Mexican scorpion Thorellius atrox using RNA-seq tandem mass spectrometry. The RNA-seq, which was performed with Illumina protocol, yielded more than 20,000 assembled transcripts. Following database search annotation strategy, 160 were identified, potentially coding for components. A novel sequence identified that codes peptide similarity to spider ω-agatoxins, act on voltage-gated calcium...
The initiation of translation via cellular internal ribosome entry sites plays an important role in the stress response and certain physiological conditions which canonical cap-dependent is compromised. Currently, only a limited number these regulatory elements have been experimentally identified. Notably, lack conservation both primary sequence mRNA secondary structure, rendering their identification difficult. Despite biological importance, currently available computational strategies to...
Metabolic reactions are chemical transformations commonly catalyzed by enzymes. In recent years, the explosion of genomic data and individual experimental characterizations have contributed to construction databases methodologies for analysis metabolic networks. Some based on graph theory organize compound networks into functional categories without preserving biochemical pathways. Other methods group exchange atom flow trace conversion substrates products in detail, which is useful...