A5084025129- Mosquito-borne diseases and control
- Viral Infections and Vectors
- Digital Rights Management and Security
- Data Mining Algorithms and Applications
- Viral Infections and Outbreaks Research
- Service-Oriented Architecture and Web Services
- Animal Disease Management and Epidemiology
- Cellular transport and secretion
- Cardiac, Anesthesia and Surgical Outcomes
- Insect symbiosis and bacterial influences
- Vibrio bacteria research studies
- Renal cell carcinoma treatment
- Virology and Viral Diseases
- Influenza Virus Research Studies
- Antimicrobial Peptides and Activities
- Vascular anomalies and interventions
- RNA and protein synthesis mechanisms
- Lipid Membrane Structure and Behavior
- Respiratory viral infections research
University Medical Center HCMC
2025
Örebro University
2020-2025
Background: Renal tumors with inferior vena cava (IVC) invasion pose significant challenges for surgical and anesthetic management. This report presents the management of a patient level 3 IVC-invading renal tumor, emphasizing complexity multidisciplinary approach required. Case Presentation: A 55-year-old woman large left tumor causing complete obstruction vein near-total IVC was admitted surgery. Multidisciplinary planning included nephrectomy removal from IVC. The underwent general...
Flaviviruses are usually transmitted to humans via mosquito or tick bites, whose infections may lead severe diseases and fatality. During intracellular infection, they remodel the endoplasmic reticulum (ER) membrane generate compartments scaffolding replication complex (RC) where of viral genome takes place. In this study, we purified ER fraction virus infected cells identify proteins that were enriched during flavivirus infection. We found tripartite motif-containing (TRIMs) including...
Potent broad-spectrum antiviral agents are urgently needed to combat existing and emerging viral infections. This is particularly important considering that vaccine development a costly time consuming process viruses constantly mutate render the ineffective. Antimicrobial peptides (AMP), such as bacteriocins, attractive candidates against enveloped viruses. One of these bacteriocins PLNC8 αβ, which consists amphipathic with positive net charges display high affinity for negatively charged...
Flaviviruses are usually transmitted to humans via mosquito or tick bites. During infection, virus replication and assembly, whose cellular sites relatively close, controlled by proteins a diverse range of host proteins. By siRNA-mediated gene silencing, we showed that ALIX CHMP4A, two members the endosomal sorting complex required for transport (ESCRT) protein machinery, during flavivirus infection. Using cell lines expressing subgenomic replicons replicon virus-like particles, demonstrated...
A prospective cohort study of avian influenza infection in poultry flocks was carried out the Mekong River Delta Viet Nam between December 2008 and April 2010. Our objectives were to (i) estimate prevalence incidence virus (ii) assess efficacy H5N1 vaccination programmes as indicated by presence H5 antibody vaccinated unvaccinated poultry. Real-time PCR multiplex assays used detect antigen viruses from swab samples. The haemagglutination inhibition test antibody. total 17 968 14 878 blood...
The endoplasmic reticulum (ER) of eukaryotic cells is a dynamic organelle, which undergoes continuous remodeling. At the three-way tubular junctions ER, lunapark (LNP) protein acts as membrane remodeling factor to stabilize these highly curved junctions. In addition, during flavivirus infection, ER invaginated form vesicles (Ve) for virus replication. Thus, LNP may have roles in generation or maintenance Ve infection. this study, our aim was characterize functions infection and investigate...
Kunjin virus (KUNV) is an attenuated strain of the severe neurotropic West Nile (WNV). The has a single-strand positive-sense RNA genome that encodes polyprotein. Following gene expression, polyprotein cleaved into structural proteins for viral packaging and nonstructural replication expression. Removal genes generate subgenomic replicons maintain capacity. Co-expression these with produces reporter virus-like particles (RVPs) which infect cells in single round. In this study, we aimed to...
Removal of genes coding for major parts capsid (C), premembrane (prM), and envelope (E) proteins on the flavivirus genome aborts production infectious virus particles where remaining forms a replicon that retains replicability in host cells. The C-prM-E can also be expressed trans with replicons to generate single-round virus-like (RVPs). In this study, we characterized use RVPs based Kunjin strain WNV (WNVKUN) as putative vaccine candidate. addition, WNVKUN were substituted Crimean-Congo...