A5082986346- Antibiotic Resistance in Bacteria
- Bacterial Identification and Susceptibility Testing
- Antimicrobial Resistance in Staphylococcus
- Clostridium difficile and Clostridium perfringens research
- Antibiotics Pharmacokinetics and Efficacy
- Gut microbiota and health
- Antibiotic Use and Resistance
- Nosocomial Infections in ICU
- Streptococcal Infections and Treatments
- Pneumonia and Respiratory Infections
- Probiotics and Fermented Foods
- Urinary Tract Infections Management
- Helicobacter pylori-related gastroenterology studies
- Otolaryngology and Infectious Diseases
- Mycobacterium research and diagnosis
- Veterinary medicine and infectious diseases
- Oral microbiology and periodontitis research
- Legionella and Acanthamoeba research
- Phenothiazines and Benzothiazines Synthesis and Activities
- Infective Endocarditis Diagnosis and Management
- Microbial Metabolites in Food Biotechnology
- Pharmaceutical and Antibiotic Environmental Impacts
- Antimicrobial Peptides and Activities
- Anesthesia and Pain Management
- Sinusitis and nasal conditions
Public Health Agency of Sweden
2016-2025
Larsen & Toubro (India)
2018
University of Copenhagen
2018
Slagelse Hospital
2018
Medical Products Agency
2006-2012
Karolinska Institutet
2000-2010
Karolinska University Hospital
2000-2010
Södertörn University
1998-2006
Charles University
2006
Umeå University
2006
<b>PURPOSE</b> Public health insurance programs have expanded coverage for the poor, and family physicians provide essential services to these vulnerable populations. Despite efforts, many Americans do not access basic medical care. This study was designed identify barriers faced by low-income parents when accessing care their children how status affects reporting of barriers. <b>METHODS</b> A mixed methods analysis undertaken using 722 responses an open-ended question on a survey instrument...
The aim was to study the long-term consequences of 1 week clindamycin administration regarding selection and persistence resistance, resistance determinants diversity Bacteroides spp. in intestinal microflora.A total 1306 isolates were collected from constitutively cultured faecal samples during a 2 year period eight healthy volunteers. strains identified by biochemical genotyping methods. MIC values determined agar dilution method presence genes screened real-time PCR.Ecological changes...
Fourteen patients with Helicobacter pylori infection were treated 20 mg omeprazole, 1 g amoxycillin and 400 metronidazole bd for 7 days (OAM), 16 250 clarithromycin (OCM). Saliva, gastric biopsies faecal samples collected before, during (day 7) 4 weeks after treatment in order to analyse alterations of the normal microflora determine antimicrobial susceptibility. Both regimens resulted marked quantitative qualitative alterations. A selection resistant streptococcal strains noticed both...
Oral administration of antibiotics for treatment urinary tract infections (UTIs) can cause ecological disturbances in the normal intestinal microflora. Poorly absorbed drugs reach colon active form, suppress susceptible microorganisms and disturb balance. Suppression microflora may lead to reduced colonization resistance with subsequent overgrowth pre-existing, naturally resistant microorganisms, such as yeasts Clostridium difficile. New by potential pathogens also occur spread within body...
Nitroimidazole resistance (nim) genes were detected in 2% of 1,502 clinical Bacteroides fragilis group strains isolated from 19 European countries, and a novel nim gene was identified. High metronidazole could be induced nim-positive strains, which emphasizes the importance acknowledging setting.
To evaluate the ecological disturbances of peroral vancomycin administration following cephalosporin administration, 20 healthy volunteers received cefuroxime axetil tablets (250 mg) perorally twice a day for 1 week, and 10 these subsequently capsules (125 four times daily 7 days. The concentration in feces after week was high (mean +/- SD, 520 197 mg/kg), which correlated with noted recipients. Vancomycin resulted rapid decrease numbers intestinal Enterococcus faecium, faecalis, durans (P <...
ABSTRACT Terminal restriction fragment length polymorphism (T-RFLP) was investigated as a tool for monitoring the human intestinal microflora during antibiotic treatment and ingestion of probiotic product. Fecal samples from eight healthy volunteers were taken before, during, after administration clindamycin. During treatment, four subjects given probiotic, placebo. Changes in microbial community composition relative abundance specific populations each subject monitored by using viable...
The incidence of fungal infections in hospitalized patients has increased, and due to demographic changes increasingly advanced medical methods, the intensive care units (ICU) have emerged as epicentres for infections. aim present study was investigate Candida colonization pattern index (CI), combination with other risk factors its relation invasive candida infection (ICI), 59 consecutive at least 7 d length stay (LOS) a multidisciplinary ICU. Surveillance samples were collected on then...
To determine whether total exposure to penicillin V can be reduced while maintaining adequate clinical efficacy when treating pharyngotonsillitis caused by group A streptococci.Open label, randomised controlled non-inferiority study.17 primary healthcare centres in Sweden between September 2015 and February 2018.Patients aged 6 years over with streptococci three or four Centor criteria (fever ≥38.5°C, tender lymph nodes, coatings of the tonsils, absence cough).Penicillin 800 mg times daily...
The characteristics of Enterococcus faecium have led to concern regarding the safety probiotics that contain this bacterium. results an in vitro filter mating assay indicate a probiotic E. strain might be potential recipient vancomycin resistance genes.
Earlier studies have reported very high (120 to 2,700 mg/kg) concentrations of norfloxacin in feces after therapeutic doses. MICs for fecal microorganisms are with few exceptions far below these levels. Nevertheless, clinical investigations show that the main part aerobic gram-positive and anaerobic microflora remains unaffected administration. In this study, binding [14C]norfloxacin material was analyzed. The a group nonlabeled quinolones interactions between Enterococcus faecium,...
The pharmacokinetics in plasma and saliva of a new ketolide, telithromycin (HMR 3647), the effect on normal oropharyngeal intestinal microflora were studied healthy volunteers compared with those clarithromycin. Ten subjects received 800 mg perorally once daily 10 other 500 clarithromycin bid for days. Blood, faecal specimens collected at defined intervals before, during after administration pharmacokinetic microbiological analyses. In receiving telithromycin, mean Cmax, AUC C24 (24 h)...
Abstract Introduction The intensive care unit is burdened with a high frequency of nosocomial infections often caused by multiresistant pathogens. Coagulase-negative staphylococci (CoNS) are reported to be the third causative agent and most frequent cause bloodstream infections. CoNS part normal microflora skin but can also colonize nasal mucosa, lower airways invasive devices. main aim present study was investigate colonization rate cross-transmissions between intubated patients in...
The increasing problem of antibiotic resistance among pathogenic bacteria requires development new antimicrobial agents. One line investigation is the synthesis hybrid peptides. aim present was to determine in vitro activities 16 cecropin-melittin peptides (CAMEL analogues) against 60 anaerobic bacterial strains, compare their with those seven clinically used agents, and different methods for susceptibility testing these stability one peptides, temporin B, stereoisomeric configurations...