A5013750554- Digital Radiography and Breast Imaging
- AI in cancer detection
- Global Cancer Incidence and Screening
- Breast Cancer Treatment Studies
- Medical Imaging Techniques and Applications
- Breast Lesions and Carcinomas
- Radiomics and Machine Learning in Medical Imaging
- Glioma Diagnosis and Treatment
- MRI in cancer diagnosis
- Cancer-related Molecular Pathways
- Cancer Risks and Factors
- Nanoplatforms for cancer theranostics
- Breast Implant and Reconstruction
- Colorectal Cancer Screening and Detection
- BRCA gene mutations in cancer
- Advanced Biosensing Techniques and Applications
- Immunotherapy and Immune Responses
- Ferroptosis and cancer prognosis
- Radiopharmaceutical Chemistry and Applications
- Cancer Cells and Metastasis
- Cancer Genomics and Diagnostics
- Cancer and Skin Lesions
- Advanced X-ray and CT Imaging
- Cancer Research and Treatments
- Cancer Immunotherapy and Biomarkers
Mayo Clinic Hospital
2016-2025
Mayo Clinic in Arizona
2016-2025
Mayo Clinic in Florida
2015-2025
WinnMed
2017-2024
AstraZeneca (United Kingdom)
2016-2023
University Hospitals of Cleveland
2023
Mayo Clinic
2021-2023
Phoenix Children's Hospital
2023
Breast Center
2023
Airedale NHS Foundation Trust
2023
Longitudinal analysis of circulating tumor DNA (ctDNA) has shown promise for monitoring treatment response. However, most current methods lack adequate sensitivity residual disease detection during or after completion in patients with nonmetastatic cancer. To address this gap and to improve minute quantities plasma, we have developed targeted digital sequencing (TARDIS) multiplexed patient-specific cancer mutations. In reference samples, by simultaneously analyzing 8 16 known mutations,...
The NCCN Guidelines for Breast Cancer Screening and Diagnosis provide health care providers with a practical, consistent framework screening evaluating spectrum of clinical presentations breast lesions. Panel is composed multidisciplinary team experts in the field, including representation from medical oncology, gynecologic surgical internal medicine, family practice, preventive pathology, diagnostic interventional radiology, as well patient advocacy. meets at least annually to review...
Background: Contrast-enhanced mammography (CEM) is growing in clinical use due to its increased sensitivity and specificity compared full-field digital (FFDM) and/or breast tomosynthesis (DBT), particularly patients with dense breasts. Objective: To perform an intraindividual comparison of MGD between FFDM, DBT, a combination protocol using both FFDM DBT (combined FFDM-DBT), CEM, undergoing cancer screening. Methods: This retrospective study included 389 women (median age, 57.4 years) at...
Potential Cost Savings of Contrast-Enhanced Digital MammographyBhavika K. Patel1, Richard J. Gray2 and Barbara A. Pockaj2Audio Available | Share
Breast Radiation Dose With CESM Compared 2D FFDM and 3D Tomosynthesis MammographyJudy R. James1, William Pavlicek1, James A. Hanson1, Thomas F. Boltz1 Bhavika K. Patel2Audio Available | Share
Image synthesis is a novel solution in precision medicine for scenarios where important medical imaging not otherwise available. The convolutional neural network (CNN) an ideal model this task because of its powerful learning capabilities through the large number layers and trainable parameters. In research, we propose new architecture residual inception encoder- decoder (RIED-Net) to learn nonlinear mapping between input images targeting output images. To evaluate validity proposed...
Inhibition of ataxia-telangiectasia mutated (ATM) during radiotherapy glioblastoma multiforme (GBM) may improve tumor control by short-circuiting the response to radiation-induced DNA damage. A major impediment for clinical implementation is that current inhibitors have limited central nervous system (CNS) bioavailability; thus, goal was identify ATM (ATMi) with improved CNS penetration. Drug screens and refinement lead compounds identified AZ31 AZ32. The were then tested
Contrast-enhanced mammography (CEM) is an imaging technique that uses iodinated contrast medium to improve visualization of breast lesions and assessment tumor neovascularity. Through modifications in x-ray energy, high- low-energy images the are combined highlight areas pooling. The use material introduces different workflows, artifacts, risks related dose. In addition, need acquire multiple each view associated with radiation Although CEM conventional share many underlying principles, it...
PURPOSE Contrast-enhanced mammography (CEM) and magnetic resonance imaging (MRI) have shown similar diagnostic performance in detection of breast cancer. Limited CEM data are available for high-risk cancer screening. The purpose the study was to prospectively investigate efficacy supplemental screening elevated risk patients. MATERIALS AND METHODS A prospective, single-institution, institutional review board–approved observational conducted asymptomatic women age 35 years or older who had a...
Purpose To evaluate heterogeneity within tumor subregions or “habitats” via textural kinetic analysis on breast dynamic contrast‐enhanced magnetic resonance imaging (DCE‐MRI) for the classification of two clinical prognostic features; 1) estrogen receptor (ER)‐positive from ER‐negative tumors, and 2) tumors with four more viable lymph node metastases after neoadjuvant chemotherapy without nodal metastases. Materials Methods Two separate volumetric DCE‐MRI datasets were obtained at 1.5T,...
Contrast-enhanced digital mammography (CEDM) is the only imaging modality that provides both (a) a high-resolution, low-energy image comparable to of and (b) contrast-enhanced similar magnetic resonance imaging. We report initial 208 CEDM examinations performed for various clinical indications provide illustrative case examples. Given its success in recent studies our experience primarily as diagnostic adjunct, can potentially improve breast cancer detection by combining low-cost conclusions...
Background: Latinas with mammographic dense breasts are at increased risk of breast cancer. This randomized controlled trial tests the effectiveness three density (BD) educational approaches on adherence to subsequent mammography screening among receiving care a Federally Qualified Health Center (FQHC). Measure(s): Adherence was ascertained using electronic health record and survey responses. Kaplan-Meier estimates time mammogram were used obtain rates 1- 2-years post baseline mammogram. Cox...