A5100401831- Respiratory viral infections research
- Pneumonia and Respiratory Infections
- Influenza Virus Research Studies
- Neonatal Respiratory Health Research
- Congenital Diaphragmatic Hernia Studies
- Tracheal and airway disorders
- COVID-19 epidemiological studies
- Viral gastroenteritis research and epidemiology
- Viral Infections and Vectors
- Glaucoma and retinal disorders
- Effects and risks of endocrine disrupting chemicals
- COVID-19 Clinical Research Studies
- Respiratory Support and Mechanisms
- Mathematical Biology Tumor Growth
- Intraocular Surgery and Lenses
- Wheat and Barley Genetics and Pathology
- Heavy Metal Exposure and Toxicity
- Ferroptosis and cancer prognosis
- Genetics and Plant Breeding
- Dialysis and Renal Disease Management
- Evolution and Genetic Dynamics
- Media Studies and Communication
- Diet and metabolism studies
- Iron Metabolism and Disorders
- Birth, Development, and Health
Shanghai Ocean University
2012-2025
Fujian Institute of Oceanography
2024-2025
Ministry of Natural Resources
2024-2025
Fujian Agriculture and Forestry University
2024-2025
University of Edinburgh
2018-2025
Nanjing Medical University
2010-2025
Changzhou Third People's Hospital
2024-2025
Guilin Medical University
2021-2025
Eastern Michigan University
2018-2025
Hainan Medical University
2025
A new ecologically inspired paradigm in cancer treatment known as "adaptive therapy" capitalizes on competitive interactions between drug-sensitive and drug-resistant subclones. The goal of adaptive therapy is to maintain a controllable stable tumor burden by allowing significant population treatment-sensitive cells survive. These, turn, suppress proliferation the less-fit resistant populations. However, there remain several open challenges designing therapies, particularly extending these...
Nonpharmaceutical interventions (NPIs) were widely introduced to combat the coronavirus disease 2019 (COVID-19) pandemic. These also likely led substantially reduced activity of respiratory syncytial virus (RSV). From late 2020, some countries observed out-of-season RSV epidemics. Here, we analyzed role NPIs, population mobility, climate, and severe acute syndrome 2 circulation in rebound through a time-to-event analysis across 18 countries. Full (re)opening schools was associated with an...
Abstract Ferroptosis has been linked to the pathogenesis of hepatic injury induced by ischemia/reperfusion (I/R). However, mechanistic basis remains unclear. In this study, using a mouse model I/R injury, it is observed that glutathione (GSH) and cysteine depletion are associated with deficiency reducing power nicotinamide adenine dinucleotide phosphate (NADPH). Genes involved in maintaining NADPH homeostasis screened, identified I/R‐induced ferroptosis significantly reduced expression...
Respiratory syncytial virus (RSV) has posed substantial morbidity and mortality burden to young children older adults globally. The coronavirus disease 2019 (COVID-19) pandemic was reported have altered RSV epidemiology could important implications for prevention control strategies. We aimed compare in different phases of the COVID-19 with pre-pandemic period by leveraging epidemiological, molecular, serological data collected from a prospective respiratory pathogen surveillance serology study.
Respiratory syncytial virus (RSV) represents a substantial global health challenge, with disproportionately high disease burden in low-income and middle-income countries. RSV exhibits seasonality most areas globally, comprehensive understanding of within-country variations could help to define the timing immunisation programmes. This study focused on China, aimed describe geographical distribution seasonality, identify distinct transmission zones, evaluate potential suitability seasonal...
Abstract Background Knowledge on age-specific hospitalizations associated with RSV infection is limited due to testing, especially in older children and adults whom infections are not expected be severe. Burden estimates based coding of hospital admissions known underestimate the burden RSV. We aimed provide robust reliable RSV-associated data respiratory from national health registers laboratory-confirmed cases Methods conducted multiseason regression analysis weekly influenza as...
BackgroundRespiratory syncytial virus (RSV) is the predominant cause of clinical pneumonia among infants and young children, often peaking during winter months in temperate regions.AimTo describe RSV seasonality 13 European countries examine its association with meteorological factors.MethodsWe included weekly data from between week 40 2010 39 2019. Using local weighted regression method, we modelled activity factors using 2010/11 to 2017/18 season. We predicted 2018/19 season across 41...