- Pancreatic and Hepatic Oncology Research
- Pancreatitis Pathology and Treatment
- Gallbladder and Bile Duct Disorders
- Neuroendocrine Tumor Research Advances
- Hepatocellular Carcinoma Treatment and Prognosis
- Gastrointestinal disorders and treatments
- Pediatric Hepatobiliary Diseases and Treatments
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Cardiac, Anesthesia and Surgical Outcomes
- Liver Disease Diagnosis and Treatment
- COVID-19 and healthcare impacts
- Healthcare cost, quality, practices
- Surgical Sutures and Adhesives
- Esophageal and GI Pathology
- Palliative Care and End-of-Life Issues
- Reconstructive Surgery and Microvascular Techniques
- Renal cell carcinoma treatment
- Selenium in Biological Systems
- Surgical site infection prevention
- Congenital Anomalies and Fetal Surgery
- Cancer Mechanisms and Therapy
- Ion Transport and Channel Regulation
- Colorectal Cancer Screening and Detection
- Appendicitis Diagnosis and Management
- Cancer survivorship and care
Indiana University
2019-2023
Indiana University – Purdue University Indianapolis
2019-2022
Indiana University School of Medicine
2019-2022
Indiana University Health
2019-2021
Indianapolis Zoo
2020
University of Toronto
2020
University Surgical Associates
2019
Murray State University
2014
Select patients with anatomically favorable walled off pancreatic necrosis may be treated by endoscopic (Endo-TGD) or operative (OR-TGD) transgastric debridement (TGD). We compared our experience these 2 approaches.Select necrotizing pancreatitis (NP) are suitable for TGD which accomplished endoscopically surgically. Limited exists contrasting techniques exists.Patients undergoing Endo-TGD and OR-TGD at a single, high-volume center between 2008 2019 were identified from prospective database....
We sought to determine if interleukin (IL)-1β and prostaglandin E2 (PGE2) (inflammatory mediators in pancreatic fluid) together with serum carbohydrate antigen (CA) 19-9 could better predict intraductal papillary mucinous neoplasm (IPMN) dysplasia than individual biomarkers alone.Pancreatic cyst fluid (n = 92) collected via endoscopy or surgery (2003-2016) was analyzed for PGE2 IL-1β (enzyme-linked immunosorbent assay). Patients had surgical pathology-proven IPMN. Threshold values (PGE2...
Objectives A proteomic discovery study was performed to determine if urine possesses a unique biosignature that could form the basis for noninvasive test able predict intraductal papillary mucinous neoplasm (IPMN) dysplasia. Methods Urine collected from patients undergoing surgery IPMN (72 low/moderate, 27 high-grade/invasive). Quantitative mass spectrometry-based proteomics performed. Proteins of interest were identified by differential expression analysis followed principal component...
The accuracy of hepatobiliary scintigraphy to assess gallbladder function remains controversial. National supply shortages pharmaceutical-grade cholecystokinin led the use an oral fatty meal stimulate contraction during scintigraphy. goal this study was compare predictive indices and ingestion for stimulation contraction.Patients evaluated with iminodiacetic acid scan from 2014 2017 were reviewed grouped based on testing stimulant (fatty versus cholecystokinin). Patients who later underwent...
Background/Aim: We created a novel, preoperative wellness program (WP) that promotes recovery. This study assessed its impact on patient outcomes after pancreatectomy. Patients and Methods: Pancreatoduodenectomies (PD) distal pancreatectomies (DP) performed from 2015 to 2018 were reviewed using our institutional NSQIP database. in the WP had their medical conditions optimized provided with following: chlorhexidine, topical mupirocin, incentive spirometer, immune-nutrition supplements....
Secretin-induced duodenal aspiration (SIDA) of pancreatic duct fluid has been proposed for neoplasm screening in very high-risk patients. We sought to determine the clinical yield and safety commercially-analyzed SIDA samples patients at moderately elevated risk.
Objectives The yield of genetic testing main pancreatic duct (MPD) fluid collected during endoscopic retrograde cholangiopancreatography (ERCP) versus ultrasound-guided fine-needle aspiration is unclear. Methods Consecutive MPD samples obtained by ultrasound/ERCP with DNA profiling were reviewed, excluding specimens designated “no amplification.” Invasive disease included invasive cancer or malignant cytology. Results One hundred ten from 109 patients who underwent ERCP (n = 32) 78) analyzed...