The aim of this study was to evaluate serum levels inducible nitric oxide synthase (INOS), myeloperoxidase (MPO), total antioxidant status (TAS), and oxidative (TOS) in women with primary ovarian insufficiency (POI) compare them healthy fertile women. We also examined the possible risk factors associated POI.This cross-sectional case control conducted Zekai Tahir Burak Women's Health Education Research Hospital. population consisted 44 POI (study group) 36 (control group). In all patients,...

Pre-eclampsia is the result of impaired trophoblast invasion and spiral artery remodeling managed by inflammatory response in its etiology physiopathology. The aim this study was to compare serum molecules including IL-33, ADAMTS12, ADAMTS16 ADAMTS18 levels between pre-eclampsia control groups investigate role these pre-eclampsia.Forty-one women diagnosed as 30 40 weeks gestation 41 non-complicated pregnant were enrolled cross-sectional, case-control prospective study. ELISA method used...

To assess hysteroscopic findings in patients with two, three, and four or more, consecutive miscarriages, to compare the prevalence of uterine abnormalities between women different numbers such miscarriages.Two hundred sixty-five two more miscarriages were enrolled study. Patients divided into three groups according number their miscarriages: Group 1 (two n = 151), 2 (three miscariages, 69), 3 (four 45). All participants underwent a diagnostic hysteroscopy. Congenital (arcuate uterus,...

Objective. We aimed to investigate possible alterations in circulating levels of the high sensitivity (hs)-C-reactive protein (CRP) reflecting tissue inflammation patients who conceived with an intrauterine device (IUD) and pregnancies after IUD removal early pregnancy.Methods. Serum hs-CRP were measured 30 pregnant women retained 18 pregnancy. Rates total miscarriage, premature rupture membranes (PROMs), low birth weight, placental abruption, preterm delivery also documented.Results. CRP...

To evaluate the risk factors for endometrial hyperplasia concomitant polyps in pre- and post-menopausal women.A total of 203 patients undergoing sampling before hysterectomy were evaluated this retrospective study. Data recorded age, gravidity, parity, body mass index (BMI: weight(kg)/height(m)2), thickness (ET), menopausal status, presence adenomyosis diabetes mellitus.Endometrial detected 13 patients. There statistically significant differences terms morbid obesity mellitus (p<0.005)....

A disintegrin-like and metalloproteinase domain with thrombospondin-type 1 motifs (ADAMTS) protein superfamily includes 19 secreted metalloproteases. Proteolytic substrates of ADAMTS enzymes have been linked to female reproductive function. Herein, we aimed investigate serum ADAMTS-1, -9 -20 levels in women without endometrial polyps (EPs). The study group (n = 40) consisted who had hysteroscopically detected histologically confirmed EPs whereas control was recruited from those any...

Objective:The aims of this study were to assess the relationship between early miscarriages and vascular endothelial growth factor (VEGF) expression determine serum levels first-trimester maternal alpha-fetoprotein (AFP) human chorionic gonadotropin (β-hCG) as markers angiogenesis predictors abortion intrauterine fetal loss. Material Methods:The present was a prospective, singlecenter, randomized controlled clinical trial.Ninety-five women who 6-10 weeks pregnant May June 2010 included in...

The objective of this study is to evaluate fetal and maternal outcomes twin pregnancies with intrauterine single death. In 13 cases, death one fetus was found during the first trimester; in 25 it after trimester. Obstetric complications fibrinogen levels were compared. There no significant differences number preterm delivery, preeclampsia, growth restriction there gestational age at delivery birth weight between groups. Coagulation disorders did not occur. risk for adverse pregnancy a...

The gonadotropin-releasing hormone-agonist (GnRH-a) treatment during in vitro fertilization (IVF) sometimes causes a functional ovarian cyst the administration period before gonadotropin stimulation, as an undesired event. aim of this study was to analyze effect these cysts on IVF outcomes.Out 981 cycles, 78 with were retrospectively analyzed respect demographic characteristics, hormonal outcomes, and fertilization, implantation clinical pregnancy rates.The metaphase II oocyte ratio, rate...

A disintegrin-like and metalloproteinase domain with thrombospondin-type 1 motifs (ADAMTS) protein superfamily includes 19 secreted metalloproteases. Proteolytic substrates of ADAMTS enzymes have been linked to reproductive function. The aim this study was investigate serum ADAMTS-3, -13, -16, -19 levels in women habitual abortions compared those healthy controls. total 86 were enrolled prospective case-control study. values recorded analyzed association demographic clinical parameters....

Antiphospholipid syndrome, uterine anomalies, and chromosomal aberrations are identifiable causes of recurrent pregnancy loss (RPL). Herein, our aim is to investigate the relationship between celiac disease (CD) specific antitransglutaminase antibodies (ATA) unexplained RPL.This was a cross sectional case-control study conducted on 86 women (45 RPL 41 controls) in tertiary level maternity hospital. Elisa kit used determine ATA IgA IgG levels.One (2.2%) patient with positivity present group....

Sirtuin 1 has an important role in cellular processes, including apoptosis and stress. The purpose of this study was to assess serum sirtuin levels women with recurrent implantation failure (RIF). In cross-sectional study, we included 28 RIF, 29 healthy who had conceived by vitro fertilization (IVF), 30 a 1-cycle IVF as controls. Human nicotinamide adenine dinucleotide (NAD)-dependent deacetylase sirtuin-1 (SIRT1/SIRT2L1) were detected using commercial colorimetric kit. Recurrent patients...

Early ovarian hyperstimulation syndrome is an acute consequence of the excessive response to gonadotropin stimulation and has a higher risk preclinical miscarriage. We reported case ongoing twin pregnancy in obese patient with polycystic ovary disease, critical early liver dysfunction. This demonstrates severity gastrointestinal symptoms dysfunction that can occur syndrome. tried focus on pathogenesis dysfunction, which rare life-threatening complication suggested strategies prevent similar...