- Genomics and Phylogenetic Studies
- Bacteriophages and microbial interactions
- Microbial Community Ecology and Physiology
- Machine Learning in Bioinformatics
- Plant Virus Research Studies
- Bioinformatics and Genomic Networks
- Monoclonal and Polyclonal Antibodies Research
- Viral gastroenteritis research and epidemiology
- Pressure Ulcer Prevention and Management
- Indoor Air Quality and Microbial Exposure
- Microbial infections and disease research
- Physical Education and Training Studies
- Air Quality and Health Impacts
- Remote Sensing and LiDAR Applications
- SARS-CoV-2 and COVID-19 Research
- Microbial Fuel Cells and Bioremediation
- Gene expression and cancer classification
- Advanced Neural Network Applications
- Marine Bivalve and Aquaculture Studies
- 3D Surveying and Cultural Heritage
- Liver Disease and Transplantation
- Data Management and Algorithms
- Metal Extraction and Bioleaching
- Air Quality Monitoring and Forecasting
- Liver physiology and pathology
City University of Hong Kong
2022-2024
Tianjin University of Traditional Chinese Medicine
2024
Beijing University of Civil Engineering and Architecture
2022-2023
Jinan University
2019-2022
Ocean University of China
2022
Dragomanov Ukrainian State University
2022
Shenyang Sport University
2022
Shanghai Institute of Materia Medica
2021
Chinese Academy of Sciences
2021
University of Chinese Academy of Sciences
2021
There is accumulating evidence showing the important roles of bacteriophages (phages) in regulating structure and functions microbiome. However, lacking an easy-to-use integrated phage analysis software hampers microbiome-related research from incorporating phages analysis.In this work, we developed a web server, PhaBOX, which can comprehensively identify analyze contigs metagenomic data. It supports analysis, including contig identification assembly, lifestyle prediction, taxonomic...
Temperature is an important factor affecting the growth, development and survival of marine organisms. A short episode high temperature has been proven to be a severe threat sustainable shellfish culture. Zhikong scallop (Chlamys farreri), with broad economic biological value in North China, frequently experienced heat stress summer recent years. To understand effects on shellfish, metabolism C. farreri was analyzed after exposure 27 °C for either 6 h or 30 d. After exposure, total 326 264...
Abstract Motivation As viruses that mainly infect bacteria, phages are key players across a wide range of ecosystems. Analyzing phage proteins is indispensable for understanding phages’ functions and roles in microbiomes. High-throughput sequencing enables us to obtain different microbiomes with low cost. However, compared the fast accumulation newly identified phages, protein classification remains difficult. In particular, fundamental need annotate virion proteins, structural such as major...
Abstract Motivation Viruses, with their ubiquitous presence and high diversity, play pivotal roles in ecological systems have significant implications for public health. Accurately identifying these viruses various ecosystems is essential comprehending variety assessing influence. Metagenomic sequencing has become a major strategy to survey the ecosystems. However, accurate comprehensive virus detection metagenomic data remains difficult. Limited reference sequences prevent alignment-based...
Viruses, with their ubiquitous presence and high diversity, play pivotal roles in ecological systems public health. Accurate identification of viruses various ecosystems is essential for comprehending variety assessing influence. Metagenomic sequencing has become a major strategy to survey the ecosystems. However, accurate comprehensive virus detection metagenomic data remains difficult. Limited reference sequences prevent alignment-based methods from identifying novel viruses. Machine...
Road high-precision mobile LiDAR measurement point clouds are the digital infrastructures for maps, autonomous driving, twins, etc. High-precision automated semantic segmentation of road is a crucial research direction. Aiming at problem low accuracy existing deep learning networks inhomogeneous sparse system measurements (MLS), method that adaptively adjusts sampling radius region groups according to density proposed. We construct dataset based on self-developed train and test segmentation....
Bacteriophages (phages for short), which prey on and replicate within bacterial cells, have a significant role in modulating microbial communities hold potential applications treating antibiotic resistance. The advancement of high-throughput sequencing technology contributes to the discovery phages tremendously. However, taxonomic classification assembled phage contigs still faces several challenges, including high genetic diversity, lack stable taxonomy system limited knowledge annotations....
Abstract Motivation Protein embedding, which represents proteins as numerical vectors, is a crucial step in various learning-based protein annotation/classification problems, including gene ontology prediction, protein-protein interaction and structure prediction. However, existing embedding methods are often computationally expensive due to their large number of parameters, can reach millions or even billions. The growing availability large-scale datasets the need for efficient analysis...
Vaccines and antibody therapeutic are needed to fight the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that has spread since 2020. Experimental studies have shown E484K variant may escape neutralization of antibodies. To explore potential impact mutation on binding affinity, we calculated free energy 28 antibodies wild type K484 mutant spike protein SARS-CoV-2. We found 71% show lower affinity mutant, indicating highly possible immune risk mutated virus. Further analysis...
After a preliminary study on the swell-shrink characteristic of red clay somewhere in Chongqing under effect dry and wet circulation through laboratory geotechnical experiment, order to improved soil function dry-wet circulation, two admixtures lime cement were added clay. The results show that: Under same load condition, deformation modified decreases gradually with increase number finally reach stable. vertical load. conclusions have some reference value for engineering construction...
Bacteriophages are viruses that target bacteria, playing a crucial role in microbial ecology. Phage proteins important understanding phage biology, such as virus infection, replication, and evolution. Although large number of new phages have been identified via metagenomic sequencing, many them limited protein function annotation. Accurate annotation presents several challenges, including their inherent diversity the scarcity annotated ones. Existing tools yet to fully leverage unique...
Bacteriophages are viruses that target bacteria, playing a crucial role in microbial ecology. Phage proteins important understanding phage biology, such as virus infection, replication, and evolution. Although large number of new phages have been identified via metagenomic sequencing, many them limited protein function annotation. Accurate annotation presents several challenges, including their inherent diversity the scarcity annotated ones. Existing tools yet to fully leverage unique...
The rapid de velopment of mobile Internet and the widespread promotion smart phones provide people with good basic conditions for obtaining information sharing resources. Internet-based college sports app has become an important platform to assist expansion industry. A been developed integrate various systems more convenient services athletes. With help GPS function phone, it explores assessment enthusiasts' extracurricular physical exercises.
Motivation: As viruses that mainly infect bacteria, phages are key players across a wide range of ecosystems. Analyzing phage proteins is indispensable for understanding phages' functions and roles in microbiomes. High-throughput sequencing enables us to obtain different microbiomes with low cost. However, compared the fast accumulation newly identified phages, protein classification remains difficult. In particular, fundamental need annotate virion proteins, structural such as major tail,...
Motivation: There is accumulating evidence showing the important roles of bacteriophages (phages) in regulating structure and functions microbiome. However, lacking an easy-to-use integrated phage analysis software hampers microbiome-related research from incorporating phages analysis. Results: In this work, we developed a web server, PhaBOX, which can comprehensively identify analyze contigs metagenomic data. It supports analysis, including contig identification assembly, lifestyle...
Road high precision mobile LiDAR measurement point cloud is a digital infrastructure in the fields of map, automatic driving, High-precision semantic segmentation road key research direction at present. aiming problem that accuracy existing deep learning networks low for uneven sparse measured by system, method proposed to divide data according spatial location and considers sampling radius regional groups. According position different objects, extracts high-dimensional features points,...
The dithiothreitol (DTT) assay is widely used to characterize the Oxidation Potential (OP) of atmospheric particulate matter (PM), which can cause adverse effects on human health. However, it’s under debate chemical species determines consumption rate DTT. During January and April 2018, we measured improved DTT daily PM2.5 samples collected in Guangzhou, China with complimentary measurements water-soluble ions, organic/elemental carbon (OC/EC) metal elements. average sampled air volume...