A5051902180- Viral Infections and Vectors
- Mosquito-borne diseases and control
- Viral Infections and Outbreaks Research
- Insect symbiosis and bacterial influences
- Animal Disease Management and Epidemiology
- Vector-Borne Animal Diseases
University of Pretoria
2020-2023
The Old world Alphavirus, Middelburg virus (MIDV), is not well known and although a few cases associated with animal illness have previously been described from Southern Africa, there has no investigation into the association of human illness. current study aimed to investigate possible MIDV infection febrile or neurological manifestations in hospitalized symptomatic patients fromGauteng, South Africa.This descriptive retrospective prospective laboratory based study. Archived cerebrospinal...
Alphaviruses from Africa, such as Middelburg virus (MIDV), and Sindbis (SINV), were detected in horses with neurologic disease South but their host ranges remain unknown. We investigated the contribution of alphaviruses to infections death wildlife domestic animals this country. During 2010-2018, a total 608 clinical samples nonequine that had febrile, signs or unexplained deaths tested for alphaviruses. identified 32 (5.5%) alphavirus (9 SINV 23 MIDV), mostly neurotissue wildlife, animals,...
The prevalence and distribution of African alphaviruses such as chikungunya have increased in recent years. Therefore, a better understanding the local vectors across continent is important. Here, entomological surveillance was performed from 2014 to 2018 at selected sites north-eastern parts South Africa where been identified during outbreaks humans animals past. Mosquitoes were collected using net, CDC-light, BG-traps. An alphavirus genus-specific nested RT-PCR used for screening, positive...
Although Old World alphaviruses, Middelburg- (MIDV) and Sindbis virus (SINV), have previously been detected in horses wildlife with neurologic disease South Africa, the pathogenesis clinical presentation of MIDV SINV infections animals are not well documented. Clinical samples from across Africa acute or fatal febrile submitted between 2014–2018 were investigated. In total, 69/1084 (6.36%) 11/1084 (1.01%) tested positive for SINV, respectively, by real-time reverse transcription (RT) PCR....