A5061419838- Cardiac Imaging and Diagnostics
- Advanced MRI Techniques and Applications
- Cardiac pacing and defibrillation studies
- Advanced X-ray and CT Imaging
- Cardiovascular Function and Risk Factors
- Coronary Interventions and Diagnostics
- Cardiac Arrest and Resuscitation
- Cardiac Arrhythmias and Treatments
- Emergency and Acute Care Studies
- Trauma and Emergency Care Studies
- Cardiac Health and Mental Health
- Acute Myocardial Infarction Research
- Cardiovascular Disease and Adiposity
- Cardiac electrophysiology and arrhythmias
- Atrial Fibrillation Management and Outcomes
- Cerebrovascular and Carotid Artery Diseases
- Cardiomyopathy and Myosin Studies
- Radiation Dose and Imaging
- Cardiac, Anesthesia and Surgical Outcomes
- Medical Imaging Techniques and Applications
- COVID-19 and healthcare impacts
- Renal and Vascular Pathologies
- Cardiovascular Effects of Exercise
- Health Promotion and Cardiovascular Prevention
- Cardiovascular Health and Risk Factors
Leiden University Medical Center
2008-2023
Leiden University
2010-2023
Utrecht University
2010-2013
Netherlands Heart Institute
2010-2012
Emory University
2010
Previous studies have used semi-automated approaches for coronary plaque quantification on multi-detector row computed tomography (CT), while an automated quantitative approach using a dedicated registration algorithm is currently lacking. Accordingly, the study aimed to demonstrate feasibility and accuracy of cardiac CT software with novel 3D coregistration intravascular ultrasound (IVUS) data sets. Patients who had undergone IVUS were enrolled. Automated lumen vessel wall contour detection...
Coronary computed tomographic angiography (CCTA) is a non-invasive imaging modality for the visualization of heart and coronary arteries. To fully exploit potential CCTA datasets apply it in clinical practice, an automated artery extraction approach needed. The purpose this paper to present validate automatic centerline algorithm arteries images. based on improved version Frangi’s vesselness filter which removes unwanted step-edge responses at boundaries cardiac chambers. Building upon new...
The aim of the current study was to evaluate relationship between site latest mechanical activation as assessed with gated myocardial perfusion SPECT (GMPS), left ventricular (LV) lead position and response cardiac resynchronization therapy (CRT).The patient population consisted consecutive patients advanced heart failure in whom CRT currently indicated. Before implantation, 2-D echocardiography GMPS were performed. performed assess LV end-systolic volume (LVESV), end-diastolic (LVEDV)...
Objectives: Percutaneous coronary intervention with stent implantation is routinely performed to treat patients obstructive artery disease. However, thus far, noninvasive assessment of in-stent restenosis has been challenging. Recently, 320-row multidetector computed tomography angiography (CTA) was introduced, allowing volumetric image acquisition the heart in a single beat or gantry rotation. The aim this study evaluate diagnostic performance CTA evaluation significant restenosis. Invasive...
Despite its high prognostic value, widespread clinical implementation of 123I-meta-iodobenzylguanidine (MIBG) myocardial scintigraphy is hampered by a lack validation and standardization. The purpose this study was to assess the reliability planar 123I-MIBG in patients with heart failure (HF). Planar MIBG images 70 HF were analysed two experienced one inexperienced observer. reproducibility early delayed heart-to-mediastinum (H/M) ratios, as well washout rate (WR) calculated different...
AimsThe positive predictive value of multidetector computed tomography angiography (CTA) for detecting significant stenosis remains limited. Possibly CTA may be more accurate in the evaluation atherosclerosis rather than severity. However, a comprehensive assessment diagnostic performance comparison with both conventional coronary (CCA) and intravascular ultrasound (IVUS) is lacking. Therefore, aim study was to systematically investigate two endpoints, namely (using CCA as reference...
The aim of the current study was to evaluate feasibility phase analysis on gated myocardial perfusion SPECT (GMPS) for assessment left ventricular (LV) diastolic dyssynchrony in a head-to-head comparison with tissue Doppler imaging (TDI).The population consisted patients end-stage heart failure New York Heart Association functional class III or IV reduced LV ejection fraction ≤ 35%. calculated using TDI as maximal time delay between early peak velocities two opposing ventricle walls...
Purpose Significant obstructive coronary artery disease (CAD) is common in asymptomatic dialysis patients. Identifying these high risk patients warranted and may improve the prognosis of this vulnerable patient group. Routine catheterization incident has been proposed, but considered too invasive. CT-angiography therefore be more appropriate. However, extensive calcification, often present group, might hamper adequate lumen evaluation. The objective study was to assess feasibility Methods...
The coronavirus disease 2019 (COVID-19) pandemic challenged health care systems in an unprecedented way. Due to the enormous amount of hospital ward and intensive unit (ICU) admissions, regular came a standstill, thereby overcrowding ICUs endangering (regular COVID-19-related) critical care. Acute coordination centers were set up safely manage influx COVID-19 patients. Furthermore, treatments requiring ICU surveillance postponed leading increased waiting lists.A center organizing patient...
Abstract Objective To assess whether the COVID-19 lockdown in 2020 had negative indirect health effects, as people seem to have been reluctant seek medical care. Methods All emergency services (EMS) transports for chest pain or out-of-hospital cardiac arrest (OHCA) Dutch region Hollands-Midden (population served > 800,000) were evaluated during initial 6 weeks of and same time period 2019. The primary endpoint was number patients both cohorts. In addition, EMS evaluations ST-elevation...
Abstract Aims Postoperative atrial fibrillation (POAF) is a common complication of cardiac surgery, yet difficult to detect in ambulatory patients. The primary aim this study investigate the effect mobile health (mHealth) intervention on POAF detection after surgery. Methods and results We performed an observational cohort among 730 adult patients who underwent surgery at tertiary care hospital Netherlands. Of these patients, 365 received standard were included as historical control group,...
AimsThe aim of the present study was to evaluate whether subclinical left ventricular (LV) systolic dysfunction is independently related coronary atherosclerosis in type 2 diabetic patients and if it could provide incremental information over baseline characteristics identify high-risk patients.
Coronary atherosclerosis has been associated with the development of atrial fibrillation (AF). However, little is known about impact coronary on outcome treatment AF. The aim this study was to investigate efficacy radiofrequency catheter ablation (RFCA) for AF using multi-detector row computed tomography (MDCT).In 125 consecutive patients undergoing RFCA AF, a pre-procedural MDCT examination (coronary angiography and/or calcium score) performed evaluate presence and severity atherosclerosis....
The autonomic nervous system interacts in the pathophysiology of heart failure. Dysfunction sympathetic has been identified as an important prognostic marker patients with chronic At present, cardiac nerve imaging 123-iodine metaiodobenzylguanidine [123-I MIBG] employed most frequently for assessment innervation and activation pattern. majority studies have shown that dysfunction assessed 123-I MIBG is a powerful predictor failure mortality morbidity. Additionally, can be used prediction...
Atrial fibrillation (AF), sternal wound infection, and cardiac decompensation are complications that can occur after surgery. Early detection of these is clinically relevant, as early treatment associated with better clinical outcomes. Remote monitoring the use a smartphone (mobile health [mHealth]) might improve surgery.The primary aim this study to compare rate AF diagnosed an mHealth solution standard care. Secondary objectives include infection decompensation, well assessment quality...
aEmergency Department, Leiden University Medical Centre, Leiden, Zuid-Holland bEmergency Service Ambulance IJsselland, Zwolle, Overijssel cDepartment of Cardiology, Zuid-Holland, Netherlands Received 17 March 2020 Accepted 23 Correspondence to Barbra E. Backus, MD, Emergency the Netherlands, Tel: +06 47944555; e-mail: [email protected]