A5092177456- Esophageal Cancer Research and Treatment
- Cancer Immunotherapy and Biomarkers
- Inflammatory Biomarkers in Disease Prognosis
- Lung Cancer Diagnosis and Treatment
Fudan University Shanghai Cancer Center
2023-2025
Abstract Purpose: Preclinical model found that elective nodal irradiation (ENI) attenuated the efficacy of radiotherapy and radio-immunotherapy. However, limited clinical studies have explored correlation between radiation dose-volume parameters negative tumor draining lymph nodes (TDLNs) T-cell activation/prognosis for cancer patients treated with definitive radio(chemo)therapy. Experimental Design: Patients locally advanced esophageal undergoing chemoradiotherapy (CRT) were selected from...
<div>AbstractPurpose:<p>A preclinical model found that elective nodal irradiation attenuated the efficacy of radiotherapy (RT) and radio-immunotherapy. However, limited clinical studies have explored correlation between radiation dose–volume parameters negative tumor-draining lymph nodes (TDLN) T-cell activation/prognosis for patients with cancer treated definitive radiochemotherapy.</p>Experimental Design:<p>Patients locally advanced esophageal undergoing...
<p>Supplementary Figures</p>
Limited studies explored the relationship between lymphocyte recovery after definitive concurrent chemoradiotherapy (dCCRT) and prognosis in esophageal squamous cell carcinoma (ESCC).
Abstract Background : Few studies investigate the relationship between lymphocyte recovery after definitive concurrent chemoradiotherapy (dCCRT) and prognosis in esophageal squamous cell carcinoma (ESCC). Methods ESCC patients undergoing dCCRT with obtainable absolute counts (ALCs) at 6 months were screened from prospective trials. Population categorized according to development of G4 G1-3 ALC nadir during radiotherapy. Prognostic value survival outcomes was estimated by Cox analysis....