- Hydrogels: synthesis, properties, applications
- Polysaccharides and Plant Cell Walls
- Polysaccharides Composition and Applications
- Liver Disease Diagnosis and Treatment
- Circadian rhythm and melatonin
- Endoplasmic Reticulum Stress and Disease
- Pancreatic function and diabetes
- Nanoparticle-Based Drug Delivery
- Microbial Metabolites in Food Biotechnology
- Electrospun Nanofibers in Biomedical Applications
- Enzyme Production and Characterization
- Adenosine and Purinergic Signaling
- Adipose Tissue and Metabolism
- Biofuel production and bioconversion
- Dietary Effects on Health
- Diet, Metabolism, and Disease
- Liver physiology and pathology
- Genetics, Aging, and Longevity in Model Organisms
- Surgical Sutures and Adhesives
- Effects and risks of endocrine disrupting chemicals
- Food composition and properties
- Phagocytosis and Immune Regulation
- Plant-Microbe Interactions and Immunity
- Probiotics and Fermented Foods
- Wastewater Treatment and Nitrogen Removal
Nanjing University of Science and Technology
2016-2025
Ministry of Industry and Information Technology
2021-2025
National University of Defense Technology
2024
Shantou University
2022
First Affiliated Hospital of Shantou University Medical College
2022
Nanjing University
2002-2014
State Key Laboratory of Pharmaceutical Biotechnology
2014
China Pharmaceutical University
2012-2013
Hankou University
2013
Nanjing Tech University
2011
Salecan is a novel linear extracellular polysaccharide with backbone of 1–3-linked glucopyranosyl units. suitable for preparing hydrogels biomedical applications due to its prominent physicochemical and biological profiles. In this contribution, variety innovative semi-interpenetrating polymer network (semi-IPN) consisting poly(methacrylic acid) (PMAA) were developed via free radical polymerization controlled drug delivery. The successful fabrication the semi-IPNs was verified by Fourier...
Salecan is a novel water-soluble extracellular β-glucan produced by salt-tolerant strain Agrobacterium sp. ZX09. suitable for the fabrication of hydrogels biomedical applications due to its excellent physicochemical and biological properties. In this paper, series pH-sensitive were prepared in aqueous solution graft copolymerization acrylic acid (AA) using N,N'-methylene diacrylamide as crosslinker controlled drug delivery. The structure thermal stability resulting characterized FT-IR, XRD...
We present an improved type of food gum (salecan) based hydrogels for oral delivery insulin. Structural hydrogel formation was assessed with Fourier transform infrared spectroscopy, thermogravimetric analysis, and X-ray diffraction. found that the modulus, morphology, swelling properties can be controlled by varying salecan dose during formation. Insulin introduced into using a swelling–diffusion approach then further used drug prototype. In vitro insulin release profiles demonstrated...
Stimuli-responsive polymeric hydrogels are promising and appealing delivery vehicles for protein/peptide drugs have made with both dosage- spatiotemporal-controlled manners possible. Here a series of new Salecan-based pH-sensitive were fabricated controlled insulin via the graft copolymerization reaction between Salecan 2-acrylamido-2-methyl-1-propanesulfonic acid. In this study, on one hand, played key role in modifying structure pore size developing hydrogel. On other tuned water content...
Salecan is a novel water-soluble β-glucan produced by salt-tolerant strain Agrobacterium sp. ZX09 which was isolated from soil sample in our laboratory and the 16S rDNA sequence of this deposited GenBank database under accession number GU810841. has excellent physicochemical properties can be used industries such as food medicine. In paper, semi-interpenetrating polymer network (semi-IPN) hydrogels based on salecan polyacrylamide (PAAm) were synthesized radical...
Uncontrolled bleeding and infection following trauma continue to pose significant clinical challenges. This study employs hemoadhican (HD) polysaccharide, known for its superior hemostatic properties, as the foundational material synthesize antibacterial carbon dots (H-CDs) through a hydrothermal method at various temperatures. The H-CDs exhibiting optimal antimicrobial properties were identified via in vitro characterization. selected possess nanoscale dimensions positive surface charge....