A5000917598- Global Maternal and Child Health
- COVID-19 Impact on Reproduction
- Blood donation and transfusion practices
- SARS-CoV-2 and COVID-19 Research
- Climate Change and Health Impacts
- COVID-19 Clinical Research Studies
- Vaccine Coverage and Hesitancy
- Maternal Mental Health During Pregnancy and Postpartum
- COVID-19 and healthcare impacts
- Salmonella and Campylobacter epidemiology
- Global Health Care Issues
- COVID-19 epidemiological studies
- COVID-19 Digital Contact Tracing
- Innovative Approaches in Technology and Social Development
- HIV, Drug Use, Sexual Risk
- HIV/AIDS Research and Interventions
- Iron Metabolism and Disorders
- Primary Care and Health Outcomes
- Viral Infections and Outbreaks Research
- Health disparities and outcomes
- COVID-19 diagnosis using AI
- Technology Assessment and Management
- HIV/AIDS drug development and treatment
- Pesticide Exposure and Toxicity
- HIV Research and Treatment
Ministry of Health of the Russian Federation
2025
Ministry of Health
2012-2024
Malawi Blood Transfusion Service
2021-2024
Public Health Institute of Malawi
2018-2024
Liverpool School of Tropical Medicine
2023-2024
Universidade de Pernambuco
2022-2024
Ministry of Health
2024
Malawi-Liverpool-Wellcome Trust Clinical Research Programme
2023
University of Liverpool
2023
University of Health Science
2023
(See the Major Article by Neil et al, on pages 1091–9 and Editorial Commentary Crump, 1107–9.) Background. Salmonella enterica serovar Typhi causes an estimated 22 million cases of typhoid fever 216 000 deaths annually worldwide. We investigated outbreak unexplained febrile illnesses with neurologic findings, determined to be fever, along Malawi–Mozambique border. Methods. The investigation included active surveillance, interviews, examinations ill convalescent persons, medical chart...
Abstract Background By August 2021, the COVID-19 pandemic has been less severe in sub-Saharan Africa than elsewhere. In Malawi, there have three subsequent epidemic waves. We therefore aimed to describe dynamics of SARS-CoV-2 exposure Malawi. Methods measured seroprevalence anti-SARS-CoV-2 antibodies amongst randomly selected blood transfusion donor sera Malawi from January 2020 July 2021 using a cross-sectional study design. subset, we also assessed vitro neutralisation against original...
Outcomes of omicron-associated COVID-19 in pregnancy have not been reported from low-resource settings, and data sub-Saharan Africa before the emergence omicron are scarce. Using a national maternal surveillance platform (MATSurvey), we aimed to compare neonatal outcomes Malawi during wave preceding waves beta delta.
Background The bacterium Salmonella enterica serovar Typhi causes typhoid fever, which is typically associated with fever and abdominal pain. An outbreak of in Malawi-Mozambique 2009 was notable for a high proportion neurologic illness. Objective Describe features complicating during an Methods Persons meeting clinical case definition were identified through surveillance, laboratory confirmation by antibody testing or blood/stool culture. We gathered demographic information, examined...
ABSTRACT HIV-1 viral load (VL) testing is not widely available in resource-limited settings. The use of finger prick dried blood spot (FP-DBS) samples could remove barriers related to sample collection and transport. Measurement VL using DBS from EDTA venous (VB-DBS) place plasma has previously been validated the NucliSENS Easy-Q v2.0 assay, but information on accuracy FP-DBS for measuring limited. This prospective study, conducted at Thyolo District Hospital southern Malawi, compared levels...
Abstract Background Voluntary non‐remunerated blood donors (VNRBDs) are essential to sustain national supplies. Expanding testing capacity for the major transfusion‐transmitted infections (TTI) is crucial ensure safe products. Understanding trends in TTIs can inform prioritisation of resources. Methods We conducted a retrospective cohort data analysis routine donation collected from VNRBDs by Malawi Blood Transfusion Service January 2015 October 2021. Variables included age, occupation; and...
Background Early reports indicate that AKI is common during COVID-19 infection. Different mortality rates of due to SARS-CoV-2 have been reported, based on the degree organic dysfunction and varying from public private hospitals. However, there a lack data about among critically ill patients with COVID-19.Methods We conducted multicenter cohort study 424 adults severe acute respiratory syndrome (SARS) AKI, both associated SARS-CoV-2, admitted six ICUs in Brazil. used multivariable logistic...
Leadership, action, learning and accountability to deliver quality care for women, newborns children.
Abstract The COVID-19 global pandemic has had considerable health impact, including sub-Saharan Africa. In Malawi, a resource-limited setting in Africa, gaining access to data inform the response is challenging. Information on adherence physical distancing guidelines and reducing contacts are nonexistent, but critical understanding communicating risk, as well allocating scarce resources. We present case study which leverages aggregated call detail records into daily pipeline summarize...
Malawi, like many other countries, faces challenges in providing accessible, affordable, and quality health services to all people. The Malawian policy framework recognizes the value of communities citizens, as co-creators leaders localized innovative initiatives, such social innovations.Social innovations involve include well bring about changes institutions responsible for care delivery. In this article, we describe institutionalization process a citizen-initiated primary innovation, named...
Abstract Background The supply of blood in many low‐ and middle‐income nations Sub‐Saharan Africa (SSA) does not meet the patient care needs. Lack delay transfusion cause harm to patients slow rate progress other parts health system. Recognizing power implementation science, BLOODSAFE Program was initiated which supports three SSA research study teams one data coordinating center (DCC) with goal improve access safe SSA. Study Design Methods team Ghana is focusing on studying decreasing iron...
We used national facility-level data from all government hospitals in Malawi to examine the effects of second and third COVID-19 waves on maternal neonatal outcomes access care during September 6, 2020-October 31, 2021. The pandemic affected health not only through direct infections but also disruption system, which could have wider indirect critical outcomes. In an interrupted time series analysis, we noted a cumulative 15.4% relative increase (63 more deaths) deaths than anticipated across...
Abstract We used national facility-level data from all government hospitals in Malawi to examine the effects of second and third COVID-19 waves on maternal neonatal outcomes access care during September 6, 2020–October 31, 2021. The pandemic affected health not only through direct infections but also disruption system, which could have wider indirect critical outcomes. In an interrupted time series analysis, we noted a cumulative 15.4% relative increase (63 more deaths) deaths than...
Abstract Background and Objective Despite the Malawi Blood Transfusion Service (MBTS) increasing amount of blood collected since its inception in 2004, remains with a 27% deficit required supplies nationally. We sought to understand facilitators barriers donation among secondary school students Malawi. Methods utilised qualitative exploratory design, sample 135 participants purposefully selected from 16 schools across Data collection methods included in‐depth interviews 20 (inclusive...
Background: Climate change poses a significant threat to women’s health in sub-Saharan Africa, yet the impact of climate on maternal is rarely reported region. Using an existing National Maternal Surveillance Platform (MATSurvey), we estimated immediate Cyclone Freddy and reproductive care service indicators Malawi. Methods: We analysed aggregated facility-level data for pregnant women up 42 weeks post-partum using national MATSurvey database. compared incidences utilisation before (1...
Climate change poses a significant threat to women's health in sub-Saharan Africa, yet the impact of climate on maternal is rarely reported region. Using an existing Maternal Surveillance Platform (MATSurvey), we estimated immediate Cyclone Freddy care service indicators Malawi. We analysed facility-level data for pregnant women up 42 weeks post-partum using national MATSurvey database. compared incidences utilisation before (1 January 19 February 2023) and after (20 30 March cyclone...
Governments worldwide are increasingly interested in scaling up effective public health innovations, but it is not always easy to institutionalize arising outside the system, as a part of national delivery. Evidence on how country governments can practically achieve this limited. This article describes institutionalization Chipatala Cha Pa Foni (CCPF, Health Center by Phone) social innovation into Malawian health, and identifies positive institutional practices that local actors drew this.
Many low- and middle-income countries (LMICs) face the daunting task of digitising, maturing deciding where to invest in digital health systems. Describing facilitators barriers conducting maturity assessments how leaders can prioritise assessments. eHealth from 10 African countries, working or supporting Ministries Health's participating Leaders' Forum July 2023 September 2023. This qualitative, descriptive study utilised key informant interviews conducted via Zoom with 14 conveniently...
Abstract Background As at end of July 2021, the COVID-19 pandemic has been less severe in sub-Saharan Africa than elsewhere. In Malawi, there have two subsequent epidemic waves. We therefore aimed to describe dynamics SARS-CoV-2 exposure Malawi. Methods measured seroprevalence anti-SARS-CoV-2 antibodies among randomly selected blood donor sera Malawi from January 2020 February 2021. a subset, we also assesed vitro neutralisation against original variant (D614G WT) and Beta variant. Findings...
ABSTRACT Objective To describe the demographic characteristics, clinical manifestations, and outcomes of hospitalised pregnant recently women with COVID-19 in Malawi, a low-income country Sub-Saharan Africa. This study responds to critical gap global data. Methods A national surveillance platform was established Malawi by Ministry Health record impact on provide real-time data for decision making. We report this facility-based cohort that includes all suspected having between 2nd June 2020...