A5007545104- Metal complexes synthesis and properties
- Corrosion Behavior and Inhibition
- Free Radicals and Antioxidants
- Concrete Corrosion and Durability
- Electrochemical Analysis and Applications
- Nanocluster Synthesis and Applications
- Sulfur Compounds in Biology
- Concrete and Cement Materials Research
- Advanced Battery Materials and Technologies
- Advanced battery technologies research
- Photochromic and Fluorescence Chemistry
- Lipid Membrane Structure and Behavior
- Photochemistry and Electron Transfer Studies
- ATP Synthase and ATPases Research
- Ionic liquids properties and applications
- Advancements in Battery Materials
- Chemistry and Chemical Engineering
- CO2 Reduction Techniques and Catalysts
- Chemical Reaction Mechanisms
- Metal-Catalyzed Oxygenation Mechanisms
- Click Chemistry and Applications
- Hydrogen embrittlement and corrosion behaviors in metals
- Conducting polymers and applications
- Alzheimer's disease research and treatments
- Jury Decision Making Processes
Italian Institute of Technology
2024-2025
Marche Polytechnic University
2023-2024
University of Calabria
2017-2023
Combining inhibitors is a key strategy to increase inhibitory efficacy because of synergistic effects. In this study, green pharmaceutical inhibitor, amoxicillin (AML), was screened and compounded with potassium iodide (KI) successfully obtain highly efficient inhibitor. The results revealed that AML/KI have excellent anticorrosion ability for Q235 steel in 1 M HCl medium. At the optimal concentration ratio 2 mM AML +5 KI, inhibition efficiency up 97.7%, which significantly higher than alone...
Glutathione (GSH) is the most abundant thiol in mammalian cells and plays a crucial role maintaining redox cellular homeostasis. The thiols of two GSH molecules can be oxidized to disulfide GSSG. cytosolic GSH/GSSG ratio very high (>100), its reduction lead apoptosis or necrosis, which are interest cancer research. CuII ions efficient oxidants thiols, but with an excess GSH, CuIn(GS)m clusters formed, CuI slowly reoxidized by O2 at pH 7.4 even more lower pH. Here, aerobic oxidation was...
α-Pyridyl thiosemicarbazones (TSC) such as Triapine (3AP) and Dp44mT are a promising class of anticancer agents. Contrary to Triapine, showed pronounced synergism with CuII, which may be due the generation reactive oxygen species (ROS) by Dp44mT-bound CuII ions. However, in intracellular environment, complexes have cope glutathione (GSH), relevant reductant CuI-chelator. Here, aiming at rationalizing different biological activity Dp44mT, we first evaluated ROS production their CuII-complexes...
The NBLT additive effectively inhibits the hydrogen evolution process on aluminum anode in a 4 M NaOH electrolyte for an Al–air battery system by forming self-assembled barrier layer.
Al-air battery has been regarded as a promising new energy source. However, the self-corrosion of aluminum anode leads to loss capacity and decrease in longevity, limiting its commercial applications. Herein, indole-2-carboxylic acid (ICA) added 4 M NaOH corrosion inhibitor. Its impact on alloy enhancement functionality batteries at various concentrations have investigated. X-ray photoelectron spectroscopy (XPS), attenuated total reflection Fourier transform infrared (ATR-FTIR) spectroscopy,...
We introduce a family of membrane-targeted azobenzenes (MTs) with push-pull character as new tool for cell stimulation. These molecules are water soluble and spontaneously partition in the membrane. Upon light irradiation, they isomerize from trans to cis, changing local charge distribution thus stimulating response. Specifically, MTs photoisomerization induces clear reproducible depolarization. The most promising species, MTP2, was extensively studied. Time-resolved spectroscopy techniques...
Some microorganisms, like the aerobic soil bacteria, Oligotropha carboxidovorans, have capability to oxidize highly toxic atmospheric gas carbon monoxide (CO) into CO2 through CO dehydrogenase enzymes, whose active site contains a bimetallic MoCu center. Over last decades, number of experimental and theoretical investigations were devoted understanding mechanism oxidation and, in particular, role very stable thiocarbonate intermediate that may be formed during catalytic cycle. The occurrence...
Abstract A DFT and TDDFT study has been carried out on monomeric anthraquinones Emodin Dermocybin ( Em , Derm ) recently proposed as natural antibacterial photosensitizers able to act also against gram‐negative microbes. The computational performed considering the relative amount of neutral ionic forms each compound in water, with variation pH. occurrence both Type I II photoreactions explored computing absorption properties species, spin‐orbit coupling constants (SOC), vertical ionization...
Given the multifactorial nature and pathogenesis of Alzheimer’s disease, therapeutic strategies are addressed to combine benefits every single-target drug into a sole molecule. Quantum mechanics molecular dynamics (MD) methods were employed here investigate multitarget action boron-containing compound against disease. The antioxidant activity as radical scavenger metal chelator was explored by means density functional theory. most plausible mechanisms, which hydrogen transfer, adduct...
Abstract In the continuous effort to identify selective chelators towards bioavailable and toxic metal ions, potential selectivity of a novel N,O chelating ligand, recently synthesized claimed be able bind Cu(II) ions forming stable complexes while leaving unaltered level essential was scrutinized using combined theoretical experimental approach. A multistep synthetic procedure used synthesize whose properties along with stability formed binding and, for comparison, Fe(III) were evaluated...
Glutathione (GSH) is the most abundant thiol in mammalian cells and plays a crucial role maintaining redox state of many biomolecules, detoxification antioxidant defence. The thiols two GSH molecules can be oxidized to disulphide GSSG. cytosolic GSH/GSSG ratio very high (> 100), its decrease lead apoptosis or necrosis, which are interest cancer research. CuII ions efficient oxidants thiols, but with an excess GSH, formed CuIn(GS)m clusters only slowly re-oxidized by O2 at pH 7.4, even...
Glutathione (GSH) is the most abundant thiol in mammalian cells and plays a crucial role maintaining redox state of many biomolecules, detoxification antioxidant defence. The thiols two GSH molecules can be oxidized to disulphide GSSG. cytosolic GSH/GSSG ratio very high (> 100), its decrease lead apoptosis or necrosis, which are interest cancer research. CuII ions efficient oxidants thiols, but with an excess GSH, formed CuIn(GS)m clusters only slowly re-oxidized by O2 at pH 7.4, even...