A5066074277- Radioactive contamination and transfer
- Environmental Toxicology and Ecotoxicology
- Radioactivity and Radon Measurements
- Mercury impact and mitigation studies
- Radiation Therapy and Dosimetry
- Selenium in Biological Systems
- Carcinogens and Genotoxicity Assessment
- Effects of Radiation Exposure
- Radiation Dose and Imaging
- Air Quality and Health Impacts
- Aquatic Invertebrate Ecology and Behavior
- Radioactive element chemistry and processing
- Fish Ecology and Management Studies
- Nuclear and radioactivity studies
- Physiological and biochemical adaptations
- Toxic Organic Pollutants Impact
- DNA Repair Mechanisms
- Heavy Metal Exposure and Toxicity
- Pharmaceutical and Antibiotic Environmental Impacts
- Heavy metals in environment
- Isotope Analysis in Ecology
- Epigenetics and DNA Methylation
- Environmental DNA in Biodiversity Studies
- Genetics, Aging, and Longevity in Model Organisms
- Nuclear Issues and Defense
Prague University of Economics and Business
2024-2025
Institut de Radioprotection et de Sûreté Nucléaire
2015-2024
CEA Cadarache
2000-2023
Centre National de la Recherche Scientifique
2009-2010
Environnements et Paléoenvironnements Océaniques et Continentaux
2009
Centre Hospitalier Universitaire de Liège
2006
University of Liège
2006
Université Paris Cité
2000
Prevalence data are important for assessing the burden of disease on health care system; pituitary adenoma prevalence very scarce.The objective study was to measure clinically relevant adenomas in a well-defined population.This cross-sectional, intensive, case-finding performed three regions province Liège, Belgium, as September 30, 2005.The conducted specialist and general medical practitioner patient populations, referral hospitals, investigational centers.Three demographically...
Our aim was to investigate epigenetic changes in Daphnia magna after a 25-day chronic external γ irradiation (generation F0 exposed 6.5 μGy·h-1 or 41.3 mGy·h-1) and their potential inheritance by subsequent recovering generations, namely, F2 (exposed as germline cells F1 embryos) F3 (the first truly unexposed generation). Effects on survival, growth, reproduction were observed DNA extracted for whole-genome bisulfite sequencing all generations. Results showed effects but no effect the...
Abstract Experiments were carried out on adult male zebrafish ( Danio rerio ) to assess early changes induced by waterborne exposure different isotopic compositions of uranium (depleted associated or not with 233 U). Oxidative stress and neurotoxicity selected as effect endpoints characterize chemo‐ radiotoxicity. Catalase, glutathione peroxidase, superoxide dismutase activities total content hepatic extracts, well brain acetylcholinesterase activity bioaccumulation, measured. led decreases...
The term "bystander effect" is used to describe an effect in which cells that have not been exposed radiation are affected by irradiated though various intracellular signaling mechanisms. In this study we analyzed the kinetics and mechanisms of bystander radioadaptation embryonic zebrafish (ZF4) chronic low dose gamma rays. ZF4 were for 4 hours with total doses irradiation ranging from 0.01–0.1 Gy. two experimental conditions, transfer or culture medium results occurrence DNA double strand...
Uranium (U) presents a unique challenge for ecological risk assessments (ERA) because it induces both chemical and radiological toxicity, the relative importance of these two toxicities differs among various U source terms (i.e., natural, enriched, depleted). We present method conversion between concentrations microg L(-1)) dose rates (microGy h(-1)) defined set reference organisms, apply this to previously derived benchmarks determine extent which ensure protection, respectively, in...
Abstract The effects of waterborne uranium (U) exposure on gene expression were examined in four organs (brain, liver, skeletal muscles, and gills) the zebrafish (Danio rerio). Adult male fish exposed to three treatments: No added (control), 23 ± 6 μg U/L, 130 34 U/L. After 3, 10, 21, 28 d an 8-d depuration period, bioaccumulation analyzed. Bioaccumulation decreased significantly liver during phase, genes involved detoxification, apoptotic mechanism, immune response strongly induced. Among...
The effects of radiation on biological systems have been studied for many years, and it is now accepted that direct damage to DNA from the triggering event leading effects. In present study, induced by acute or chronic irradiation was compared at cellular (zebrafish [Danio rerio] cell line ZF4) developmental (embryo) levels. Zebrafish ZF4 cells embryos (at 3 h postfertilization) were exposed within ranges doses (0.3-2 Gy/d) dose rates (0.1-0.75 Gy/d). assessed immunodetection γ-H2AX DNA-PK...