A5087045866- Cardiac pacing and defibrillation studies
- Cardiac electrophysiology and arrhythmias
- Cardiomyopathy and Myosin Studies
- Cardiac Arrhythmias and Treatments
- Family Support in Illness
- RNA modifications and cancer
- Atrial Fibrillation Management and Outcomes
- Lysosomal Storage Disorders Research
- Palliative Care and End-of-Life Issues
- Peptidase Inhibition and Analysis
- Coenzyme Q10 studies and effects
- Blood disorders and treatments
- Systemic Lupus Erythematosus Research
- Cardiac tumors and thrombi
- Kawasaki Disease and Coronary Complications
- Vascular Malformations and Hemangiomas
- Grief, Bereavement, and Mental Health
- Childhood Cancer Survivors' Quality of Life
- Ion channel regulation and function
- Platelet Disorders and Treatments
- Neurogenetic and Muscular Disorders Research
- Hepatitis Viruses Studies and Epidemiology
- European Law and Migration
- Lipoproteins and Cardiovascular Health
Universität Hamburg
2019-2023
University Medical Center Hamburg-Eppendorf
2019-2023
Heidelberg University
2013
Abstract Aims Calmodulinopathy due to mutations in any of the three CALM genes (CALM1–3) causes life-threatening arrhythmia syndromes, especially young individuals. The International Registry (ICalmR) aims define and link increasing complexity clinical presentation underlying molecular mechanisms. Methods results ICalmR is an international, collaborative, observational study, assembling analysing genetic data on CALM-positive patients. has enrolled 140 subjects (median age 10.8 years...
Abstract Objective The results of studies concerning levels internalizing and externalizing behaviors in adolescent children with a parent suffering from cancer as compared control groups or normative data are contradictory so far. Longitudinal designs using rare. No study explicitly exploring broad range risk exists to date. Methods Therefore, 74 adolescents who have (index group) were 75 healthy parents (control several juvenile behaviors. Participants examined three times over the course...
Ultra-high density mapping (HDM) is a promising tool in the treatment of patients with complex arrhythmias. In adults congenital heart disease (CHD), rhythm disorders are among most common complications but catheter ablation can be challenging due to heterogenous anatomy and arrhythmogenic substrates. Here, we describe our initial experience using HDM conjunction novel automated annotation algorithms moderate great CHD complexity.We studied series consecutive adult complexity an indication...
Spinal muscular atrophy (SMA) is a genetic neurodegenerative disease leading to weakness and premature death. Three therapeutic options are currently available including gene replacement therapy (GRT), which potentially cardiotoxic. High-sensitive cardiac troponin I (hs-cTnI) widely used monitor potential contraindications or side effects of GRT, but reference data in healthy newborns limited lacking neonates with SMA. The aim this study determine the range pre-therapeutic hs-cTnI...
Anticipatory Grief in Adolescents and Young Adults Coping with Parental Cancer By the current state of research, it cannot be answered clearly how adolescents experience anticipatory grief if to which extent this process differs from adults. The present study will fill gap by providing both a quantitative qualitative description processes. Therefore, 74 young adults (11-21 years), whose parents have suffered cancer, completed an adapted version “Trauerfragebogen” (Weiser u. Ochsmann, 2002)....
Background: Neuralgic amyotrophy (NA) has been described as a possible extrahepatic manifestation of hepatitis E virus (HEV) infection. Usually, HEV-associated NA occurs bilaterally. The clinical characteristics determining the course have still not defined. Methods: In this retrospective multicentric case series, 16 patients with were studied and compared to 176 HEV without in terms their age, sex, ALT levels. Results: Neither gender distribution (75% vs. 67% male) nor age (47 48 years...
Reifes männliches Neugeborenes, Gestationsalter 39+0 Schwangerschaftswochen (SSW), Geburtsgewicht 4200 g, Nabelarterien-pH 7,31, APGAR 9/10/10. Geburt per primärer Sectio bei bekannter fetaler Tachykardie. Die Herzfrequenz lag postnatal 220/min; die „probatorische“ Gabe von Adenosin führte nicht zur Konversion in regulären Sinusrhythmus. pränatale Verdachtsdiagnose Vorhofflattern ließ sich im 12-Kanal-EKG bestätigen: Kammerfrequenz betrug (unter postnataler Fortsetzung der intrauterin...