A5027244262- Biosensors and Analytical Detection
- Reproductive tract infections research
- Cervical Cancer and HPV Research
- Microfluidic and Capillary Electrophoresis Applications
- Microfluidic and Bio-sensing Technologies
- Respiratory viral infections research
- Bacterial Identification and Susceptibility Testing
- Gut microbiota and health
- Urinary Tract Infections Management
- Bacteriophages and microbial interactions
- Advanced biosensing and bioanalysis techniques
- SARS-CoV-2 detection and testing
- Advanced Chemical Sensor Technologies
- Genomics and Phylogenetic Studies
- Cancer therapeutics and mechanisms
- Nanopore and Nanochannel Transport Studies
- Electrochemical sensors and biosensors
- Antimicrobial Resistance in Staphylococcus
- Immune Response and Inflammation
- Streptococcal Infections and Treatments
- Aquaculture disease management and microbiota
- Antibiotic Resistance in Bacteria
- Antimicrobial Peptides and Activities
- Innovative Microfluidic and Catalytic Techniques Innovation
- Molecular Biology Techniques and Applications
Fraunhofer Institute for Cell Therapy and Immunology
2013-2023
Fraunhofer Society
2015
Volgograd State Medical University
2010
Aim: Processing of the samples in molecular diagnostics is complex and labor-intensive. An integrated automated platform for sample preparation nucleic acid-based detection can significantly relieve this burden users. Results: We present a prototype versatile pathogens various liquid media. describe proof-of-concept isolation bacteria, cell lysis with optional DNA extraction, amplification two different reactions, loop-mediated isothermal PCR, on single microfluidic platform. Conclusion: The...
Respiratory viruses can cause epidemics or pandemics, which are worldwide outbreaks of disease. The severity these events varies depending on the virus, its characteristics, along with environmental factors. frequency and pandemics caused by respiratory is difficult to predict, but potential such underlines importance continued monitoring, research, preparation for emerging infectious diseases. To help improve pandemic preparedness, we created a fully integrated duplex reverse transcription...
A combination of Micro-Electro-Mechanical Systems and nanoscale structures allows for the creation novel miniaturized devices, which broaden boundaries diagnostic approaches. Some materials possess unique properties at nanolevel, are different from those in bulk materials. In last years these became a focus interest many researchers, as well methods production, design operation nanoobjects. Intensive research development work resulted numerous inventions, exploiting nanotechnology systems....
Abstract In this work, an approach for SPR spectroscopy using the li system is examined that combines signal amplification by PCR and magnetic nanoparticles in one injection step. Therefore, synthesis of products was performed on beads similar to a solid‐phase PCR, termed PCR‐on‐a‐bead. The functionality proven enzymatic assay. For validation detection oligonucleotides SPR, asymmetric product investigated. A increase upon binding specific probes observed. addition, surface regeneration chip...
The clinical signs of active trachoma are often present in the absence ocular Chlamydia trachomatis infection, particularly following mass drug administration. Treatment decisions impact surveys and post-control surveillance for communities currently based on prevalence signs, which may result further unnecessary distribution antibiotic treatment increased spread macrolide resistance alleles 'off-target' bacterial species. We therefore developed a simple, fast, low cost diagnostic assay...
Commonly, microfluidic devices are based on the movement of fluids. For molecular diagnostics assays which often include steps like PCR, this practically always involves a more or less complicated set external pumps, valves and liquid controls. In presented paper, we follow different approach in fluid after sample introduction remains stationary main bioactive molecules moved through chain reaction compartments contain reagents necessary for assay. The big advantage concept is lack any...
A very simple and rapid homogeneous SPARCL™ immunoassay with on-chip preserved dry reagents enables sensitive quantitative detection of biomarkers.
We assessed the viability of self-sampled gargle water direct RT-LAMP (LAMP) for detecting SARS-CoV-2 infections by estimating its sensitivity with respect to gold standard indirect RT-PCR paired oro-nasopharyngeal swab samples. also impact symptom onset test time (STT)-i.e., days at sampling, on LAMP. In addition, we appraised self-sampling versus comparing results. 202 and samples were collected from hospital patients COVID-19 associated symptoms. LAMP, performed all samples, was LAMP...
Abstract Background The clinical signs of active trachoma are often present in the absence ocular Chlamydia trachomatis infection, particularly following mass drug administration. Treatment decisions impact surveys and post-control surveillance for communities currently based on prevalence signs, which may result further unnecessary distribution antibiotic treatment increased spread macrolide resistance alleles ‘off-target’ bacterial species. We therefore developed a simple, fast, low cost...
Abstract Background The clinical signs of active trachoma are often present in the absence ocular Chlamydia trachomatis infection, particularly following mass drug administration. Treatment decisions impact surveys and post-control surveillance for communities currently based on prevalence signs, which may result further unnecessary distribution antibiotic treatment increased spread macrolide resistance alleles ‘off-target’ bacterial species. We therefore developed a simple, fast, low cost...
Abstract Background: The clinical signs of active trachoma are often present in the absence ocular Chlamydia trachomatis infection, particularly following mass drug administration. Treatment decisions impact surveys and post-control surveillance for communities currently based on prevalence signs, which may result further unnecessary distribution antibiotic treatment increased spread macrolide resistance alleles ‘off-target’ bacterial species. We therefore developed a simple, fast, low cost...