A5076868240- AI in cancer detection
- Digital Radiography and Breast Imaging
- Radiomics and Machine Learning in Medical Imaging
- Radiology practices and education
- Global Cancer Incidence and Screening
- Medical Imaging Techniques and Applications
- Radiation Dose and Imaging
- Lung Cancer Diagnosis and Treatment
- Advanced X-ray and CT Imaging
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Colorectal Cancer Screening and Detection
- Traumatic Brain Injury and Neurovascular Disturbances
- Reliability and Agreement in Measurement
- Advanced MRI Techniques and Applications
- Medical Image Segmentation Techniques
- Anesthesia and Neurotoxicity Research
- Atomic and Subatomic Physics Research
- Electrical and Bioimpedance Tomography
- Respiratory Support and Mechanisms
- Breast Lesions and Carcinomas
- Clinical Laboratory Practices and Quality Control
- Medical Coding and Health Information
- MRI in cancer diagnosis
- COVID-19 diagnosis using AI
- Nuclear Physics and Applications
University of Pittsburgh
2012-2021
Israel Institute for Biological Research
2021
Oslo University Hospital
2019
Cancer Registry of Norway
2019
University of Oslo
2019
King's College London
2016
Centro Cardiologico Monzino
2016
Institute of Experimental Cardiology
2016
Imperial College London
2016
University of Florence
2016
Purpose: The development of computer‐aided diagnostic (CAD) methods for lung nodule detection, classification, and quantitative assessment can be facilitated through a well‐characterized repository computed tomography (CT) scans. Lung Image Database Consortium (LIDC) Resource Initiative (IDRI) completed such database, establishing publicly available reference the medical imaging research community. Initiated by National Cancer Institute (NCI), further advanced Foundation Institutes Health...
Purpose To assess cancer detection rates, false-positive rates before arbitration, positive predictive values for women recalled after and the type of cancers detected with use digital mammography alone combined tomosynthesis in a large prospective screening trial. Materials Methods A prospective, reader- modality-balanced study participants undergoing plus tomosynthesis, results which were read independently by four different radiologists, is under way. The was approved regional ethics...
Digital Breast Tomosynthesis: Observer Performance StudyDavid Gur1, Gordon S. Abrams2, Denise M. Chough2, Marie A. Ganott2, Christiane Hakim2, Ronald L. Perrin2, Grace Y. Rathfon2, Jules H. Sumkin2, Margarita Zuley2 and Andriy I. Bandos3Audio Available | Share
The purpose of this article is to compare the ability digital breast tomosynthesis and full field mammography (FFDM) detect characterize calcifications.One hundred paired examinations were performed utilizing FFDM tomosynthesis. Twenty biopsy-proven cancers, 40 benign calcifications, randomly selected negative screening studies retrospectively reviewed by five radiologists in a crossed multireader multimodal observer performance study. Data collected included presence calcifications forced...
Background Digital breast tomosynthesis (DBT) is replacing digital mammography (DM) in the clinical workflow. Currently, there are limited prospective studies comparing diagnostic accuracy of both examinations and role synthetic (SM) computer-aided detection (CAD). Purpose To compare DM versus + DBT population-based cancer screening. Materials Methods This study, performed from November 2010 to December 2012, included 24 301 women (mean age, 59.1 years ± 5.7 [standard deviation]) with 281...
Background: Computer-aided mammography is rapidly gaining clinical acceptance, but few data demonstrate its actual benefit in the environment. We assessed changes recall and cancer detection rates after introduction of a computer-aided system into radiology practice an academic setting. Methods: used verified practice- outcome-related databases to compute for 24 Mammography Quality Standards Act-certified radiologists our who interpreted 115 571 screening mammograms with (n = 59 139) or...
Purpose To compare the diagnostic performance of breast tomosynthesis versus supplemental mammography views in classification masses, distortions, and asymmetries. Materials Methods Eight radiologists who specialized imaging retrospectively reviewed 217 consecutively accrued lesions by using protocols that were HIPAA compliant institutional review board approved 182 patients aged 31–60 years (mean, 50 years) underwent tomosynthesis. The cohort included 33% (72 217) cancers 67% (145 benign...
Purpose To compare radiologists' performance during interpretation of screening mammograms in the clinic with their when reading same a retrospective laboratory study. Materials and Methods This study was conducted under an institutional review board–approved, HIPAA-compliant protocol; need for informed consent waived. Nine experienced radiologists rated enriched set that they had personally read (the "reader-specific" set) mixed "common" none participants previously by using Breast Imaging...
Abstract In patients with subarachnoid hemorrhage, delayed neurological deficits, often followed by infarction, are believed to result from ischemia caused vasospasm. Cerebral blood flow (CBF) data have been useful in predicting the risk of vasospasm these and distinguishing those deficits Although CBF thresholds for infarction established animals, few clinical studies correlated values symptoms infarction. To assess sensitivity provided xenon-enhanced computed tomography (Xe/CT) define...
A noninvasive technique has been developed to measure and display local cerebral blood flow (LCBF) in vivo. In this procedure, nonradioactive xenon gas is inhaled the temporal changes radiographic enhancement produced by inhalation are measured sequential computerized tomography. The time-dependent concentrations various anatomical units brain used derive both partition coefficient LCBF. Functional mapping of with excellent specificity obtained baboon brain. response LCBF stimuli such as...
OBJECTIVE. The objective of our study was to assess ergonomic and diagnostic performance–related issues associated with the interpretation digital breast tomosynthesis–generated examinations.
Studies demonstrating an association between chronic obstructive pulmonary disease and low bone mineral density (BMD) implicate factors distinct from treatments severity of lung in the pathogenesis osteoporosis. Whereas emphysema has been independently associated with vascular other comorbidities, its BMD not well studied.
Computer-aided detection and diagnosis (CAD) systems are increasingly being used as an aid by clinicians for interpretation of diseases. mark regions image that may reveal specific abnormalities to alert these during interpretation. provide assessment a disease using image-based information alone or in combination with other relevant diagnostic data decision support developing their diagnoses. While CAD commercially available, standardized approaches evaluating reporting performance have not...
Evaluation of diagnostic performance is a necessary component new developments in many fields including medical diagnostics and decision making. The methodology for statistical analysis continues to develop, offering analytical tools conventional inferences solutions novel increasingly more practically relevant questions. In this paper, we focus on the partial area under Receiver Operating Characteristic (ROC) curve or pAUC. This summary index considered be than entire ROC (AUC), but because...
Background Staging newly diagnosed breast cancer by using dynamic contrast material-enhanced MRI is limited access, high cost, and false-positive findings. The utility of contrast-enhanced mammography (CEM) 99mTc sestamibi-based molecular imaging (MBI) in this setting largely unknown. Purpose To compare extent-of-disease assessments MRI, CEM, MBI versus pathology women with cancer. Materials Methods In HIPAA-compliant prospective study, biopsy-proven underwent between October 2014 April...
Free-response assessment of diagnostic systems continues to gain acceptance in areas related the detection, localization, and classification one or more "abnormalities" within a subject. A free-response receiver operating characteristic (FROC) curve is tool for characterizing performance system at all decision thresholds simultaneously. Although importance single index summarizing entire over well recognized ROC analysis (e.g., area under curve), currently there no widely accepted summary...
Virtually all receiver operating characteristic (ROC) studies of medical imaging methods have involved data collected on a discrete confidence-rating scale, though in principle ROC can be conducted with either or continuous scales. Continuous scales provide potential advantages applications analysis, but the possible dependence results kind scale used an observerperformance experiment has not been investigated empirically. The authors multi-observer study which radiologists read abdominal...
Identification of pulmonary fissures, which form the boundaries between lobes in lungs, may be useful during clinical interpretation computed tomography (CT) examinations to assess early presence and characterization manifestation several lung diseases. Motivated by unique nature surface shape fissures 3-D space, we developed a new automated scheme using computational geometry methods detect segment depicted on CT images. After geometric modeling volume marching cubes algorithm, Laplacian...