- Acute Ischemic Stroke Management
- Cerebrovascular and Carotid Artery Diseases
- Peripheral Neuropathies and Disorders
- Myasthenia Gravis and Thymoma
- Cardiac Arrest and Resuscitation
- Cardiovascular Disease and Adiposity
- Venous Thromboembolism Diagnosis and Management
- Stroke Rehabilitation and Recovery
- Traumatic Brain Injury and Neurovascular Disturbances
- Intracerebral and Subarachnoid Hemorrhage Research
- Migraine and Headache Studies
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Immunodeficiency and Autoimmune Disorders
- Cardiovascular Health and Disease Prevention
- Assisted Reproductive Technology and Twin Pregnancy
- Advanced Neuroimaging Techniques and Applications
- Trauma and Emergency Care Studies
- Bartonella species infections research
- Advanced Authentication Protocols Security
- Injury Epidemiology and Prevention
- Sustainable Building Design and Assessment
- Dermatological and Skeletal Disorders
- Sarcoidosis and Beryllium Toxicity Research
- Medical Imaging and Analysis
- Advanced Technologies in Various Fields
Hacettepe University Hospital
2019-2025
Istanbul Medipol University
2024-2025
Istanbul Medeniyet University
2025
Hacettepe University
2012-2024
Mersin Üniversitesi
2022
Ege University
2021
Fatih University Medical Faculty Hospital
2021
Istanbul University
2021
Adnan Menderes University
2020
İstanbul Kanuni Sultan Süleyman Eğitim ve Araştırma Hastanesi
2019
Non-invasive vagus nerve stimulation (nVNS) using a hand-held stimulator placed on the neck is an FDA-approved treatment for primary headache disorders. The safety of nVNS unknown in stroke patients.To assess and feasibility acute stroke.TR-VENUS (clinicaltrials.gov identifier NCT03733431) was randomized, sham-controlled, open-label, multicenter trial conducted patients with ischemic (IS) or intracerebral hemorrhage (ICH). Patients were randomly assigned to standard-dose nVNS, high-dose sham...
Abstract Introduction Resistance to thyroid hormone syndrome (RTH), also named Refetoff Syndrome is an autosomal dominant or recessive rare genetic disease. It’s incidence approximately 1:50.000 in newborns. Increasing awareness and knowledge about RTH will increase the diagnosis rate. So that other diseases accompany can be detected with early consultation. Clinical Case A 45-year-old female patient was consulted endocrinology department for abnormal function tests. In her medical history,...
The relationship between subclinical carotid artery atherosclerosis and sarcopenia has not been clarified in many respects. In this study, the possible composite clinical indices various levels of parameters was revisited. Ishii score (Ishii-max Ishii-average) used to determine 257 prospectively recruited healthy controls patients with neurological diseases (age: 65 ± 10 years, 50% female). Carotid distensibility (stress, strain, modulus, stiffness, distensibility), intima-media thickness...
Background: In the phase III eculizumab for refractory generalized myasthenia gravis REGAIN study [ClinicalTrials.gov identifier: NCT01997229] and its open-label extension (OLE) NCT02301624], patients with treatment-refractory antiacetylcholine receptor antibody-positive had clinically meaningful improvements versus placebo. This subgroup analysis evaluated data from a recent history of chronic intravenous immunoglobulin (IVIg) use before entry. Methods: The comprised who received IVIg at...
Inflammation indices derived from complete blood counts (CBCs) have been proposed to estimate benefit and risk of intravenous (IV) tissue plasminogen activator (tPA) in acute ischemic stroke. In 165 patients, the neutrophil-to-lymphocyte ratio (NLR), platelet–lymphocyte (PLR), lymphocyte-to-monocyte ratio, systemic immune-inflammation index (SII) were calculated before 24 hours after IV tPA. The area under receiver operating characteristic (AUC-ROC) curves, positive negative likelihood...
Background/Objectives: Studies attempting to predict the development of severe respiratory failure in patients with a COVID-19 infection using machine learning algorithms have yielded different results due differences variable selection. We aimed failure, defined as need for high-flow oxygen support, continuous positive airway pressure, or mechanical ventilation, COVID-19, identify most important variables achieving this prediction. Methods: This retrospective, cross-sectional study included...
Proteus syndrome is a rare disorder with progressive asymmetrical and disproportionate overgrowth of various tissues the body. The characterized by wide range malformations, including craniofacial deformities. Extraoral examination revealed several classical features syndrome: pronounced hemifacial hypertrophy, macrodactyly hyperostosis. Intraoral high arched palate gingival hyperplasia. Other findings were unilateral enlargement tongue, alveolar growth dilaceration roots teeth. There severe...
Background: Mutations in the glucosamine (UDP‐N‐acetyl)‐2‐epimerase/N‐acetyl mannosamine kinase (GNE) gene have previously reported children with myopathy, however, recently GNE mutations were to be causative nine thrombocytopenia without associated muscle wasting. Aims: Here we share our experience of a child macrothrombocytopenia wasting GNE. Methods: The clinical and genetic features is Results: A 30‐day‐old male was referred Pediatric Hematology Clinic Erciyes University complaints...
The importance of Carotid Artery Perivascular Adipose Tissue Density (CAPATd), a parameter that can be readily evaluated on emergency computed tomographic angiography (CTA), in acute stroke has not been adequately clarified. We created exploratory logistic regression models to detect the interaction between effect CAPATd and intravenous (IV) tissue plasminogen activator (tPA) 174 patients (mean age 71 ± 14 years, 94 women) with ischemic treated IV-tPA alone. CAPATd-average mean (−60.6 18.7...
Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)
Introduction: The adequacy of blood flow from the leptomeningeal collaterals is considered one most important factors determining rate infarct progression and response to acute stroke treatments in setting large vessel occlusions. Several patient-related variables, including age, vascular risk factors, laboratory parameters, have been proposed explain interindividual variability collateral among patients. This study aimed assess how pre-stroke frailty, an aging-related syndrome characterized...
The role of arterial collateral and venous outflow status on the response to intravenous tissue plasminogen activator (IV-tPA) has not been sufficiently clarified in acute major cerebral occlusions. A total 130 patients (mean age: 71 years; 73 females) with middle artery M1/M2 segment or terminal internal carotid occlusion treated solely IV-tPA were analyzed. Regional leptomeningeal score (rLMC) was used for scoring, cortical vein opacification (COVES) modified Prognostic Evaluation based...