Chee‐Yan Choo

ORCID: 0000-0002-9084-4818
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About
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Research Areas
  • Phytochemical compounds biological activities
  • Traditional and Medicinal Uses of Annonaceae
  • Natural Antidiabetic Agents Studies
  • Natural product bioactivities and synthesis
  • Cholinesterase and Neurodegenerative Diseases
  • Phytochemistry and biological activities of Ficus species
  • Synthesis of Organic Compounds
  • Allelopathy and phytotoxic interactions
  • Phytochemistry and biological activity of medicinal plants
  • Cocoa and Sweet Potato Agronomy
  • Computational Drug Discovery Methods
  • Plant Genetic and Mutation Studies
  • Online and Blended Learning
  • Pharmacology and Obesity Treatment
  • Toxin Mechanisms and Immunotoxins
  • Pharmacological Effects of Natural Compounds
  • Technology-Enhanced Education Studies
  • Medicinal Plants and Neuroprotection
  • Medicinal Plants and Bioactive Compounds
  • Innovative Teaching Methods
  • Plant tissue culture and regeneration
  • Phytochemistry and Biological Activities
  • Hibiscus Plant Research Studies
  • Moringa oleifera research and applications
  • Ethnobotanical and Medicinal Plants Studies

Universiti Teknologi MARA
2016-2025

National University of Malaysia
2014

Tokyo University of Pharmacy and Life Sciences
2000-2013

Hoshi University
2005-2006

Hospital Universiti Sains Malaysia
1998-2005

Universiti Sains Malaysia
2000-2004

University of the Sciences
2001

Hokkaido University
2000

This article explored the potential applications, benefits, and risks of using ChatGPT in medical health sciences research. The experimental study was performed with content analysis benefits shows many average experts’ appropriateness accuracy rates eight research themes were between 60% 95%. concludes that could help researchers, especially new caution aspects is still early phase use by researchers worldwide, its ability to will be better soon. Attending training workshops about AI very...

10.36877/pmmb.a0000337 article EN cc-by-nc Progress In Microbes & Molecular Biology 2023-06-21

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTConditioned Polyethylene as a Permselective Membrane. Separation of Isomeric XylenesA. S. Michaels, R. F. Baddour, H. J. Bixler, and C. Y. ChooCite this: Ind. Eng. Chem. Process Des. Dev. 1962, 1, 14–25Publication Date (Print):January 1962Publication History Published online1 May 2002Published inissue 1 January 1962https://doi.org/10.1021/i260001a003RIGHTS & PERMISSIONSArticle Views214Altmetric-Citations73LEARN ABOUT THESE METRICSArticle Views are...

10.1021/i260001a003 article EN Industrial & Engineering Chemistry Process Design and Development 1962-01-01

Eurycomanone and eurycomanol are two quassinoids from the roots of Eurycoma longifolia Jack. The aim this study was to assess bioactivity these compounds in Jurkat K562 human leukemia cell models compared peripheral blood mononuclear cells healthy donors. Both eurycomanone inhibited viability proliferation without affecting cells. Interestingly, NF-κB signaling through inhibition IκBα phosphorylation upstream mitogen activated protein kinase (MAPK) signaling, but not eurycomanol. In...

10.3390/molecules190914649 article EN cc-by Molecules 2014-09-16

The methanolic extract of the leaves CASSIA ALATA was sequentially partitioned in increasing polarity to afford hexane, chloroform, butanol and residual extract. Crude extracts were evaluated against MRSA using agar well diffusion assay. chloroform both exhibited inhibition with indexes 1.03 +/- 0.16 0.78 0.07 at concentration 50 mg/mL. further purified silica gel reverse phase chromatography kaempferol ( 1), 3- O-beta-glucopyranoside 2), O-gentiobioside 3) aloe emodin 4). four constituents...

10.1055/s-0028-1088340 article EN Planta Medica 2008-11-07

ABSTRACT Objectives This study aims to establish the effect of bruceine E in attenuating nonalcoholic steatohepatitis (NASH) through PI3K/AKT/NFκB pathway. Methods High-fat-diet (HFD) male Wistar rats were orally administered with glibenclamide (20 mg/kg) or (400, 800, 1600 µg/kg) for 4 weeks. After weeks treatment, blood serum was analysed liver markers. Liver histology used identify degree inflammation. The tissue evaluated on phosphoinositide 3-kinase/protein kinase B (PI3K/AKT) and...

10.1093/jpp/rgaf016 article EN Journal of Pharmacy and Pharmacology 2025-05-07

Two new cyclic peptides, dichotomins J (1) and K (2), have been isolated from the roots of Stellaria dichotoma, their structures were elucidated by chemical degradation extensive 2D NMR methods. Dichotomins (2) showed a moderate vasorelaxant effect on rat aorta.

10.1021/np050262k article EN Journal of Natural Products 2005-11-01

Ficus deltoidea Jack (Moraceae) leaf extract is used as an antidiabetic in traditional medicine. Its widespread usage reflected by the available preparations present commercial market. The efficacy of other species has not been entirely satisfactory and many herbs have demonstrated poor safety profiles. This study examined hypoglycemic toxicity profiles F. rodent models. Extracts dried powdered leaves were obtained using methanol solution, n-hexane, chloroform, n-butanol. These extracts...

10.2202/1553-3840.1469 article EN Journal of Complementary and Integrative Medicine 2011-02-10

An analytical method using HPLC with UV detection was developed to investigate the quassinoid content of Eurycoma longifolia Jack (Simaroubaceae) collected from various sources. Eurycomanone (1), longilactone (2), 14,15β-dihydroxyklaineanone (3), 15β-acetyl-14-hydroxyklaineanone (4), 6α-hydroxyeurycomalactone (5), and eurycomalactone (7) were isolated as reference standards together synthesized 1β,12α,15β-triacetyleurycomanone (6, internal standard), identified by NMR, MS, IR spectroscopies....

10.1055/s-2006-957570 article EN Planta Medica 1998-12-01

ADVERTISEMENT RETURN TO ISSUEPREVNoteNEXTSamoquasine A, a Benzoquinazoline Alkaloid from the Seeds of Annona squamosaHiroshi Morita, Yumiko Sato, Kit-Lam Chan, Chee-Yan Choo, Hideji Itokawa, Koichi Takeya, and Jun'ichi KobayashiView Author Information Graduate School Pharmaceutical Sciences, Hokkaido University, Sapporo 060-0812, Japan, Universiti Sains Malaysia, 11800 Penang, Pharmacy, Tokyo University Pharmacy & Life Science, 1432-1 Horinouchi, Hachioji, 192-03, Japan Cite this: J. Nat....

10.1021/np000342i article EN Journal of Natural Products 2000-11-08
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