Shakila Harshavardhan

ORCID: 0000-0002-9093-5621
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About
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Research Areas
  • Tuberculosis Research and Epidemiology
  • Leptospirosis research and findings
  • Viral Infectious Diseases and Gene Expression in Insects
  • Medicinal Plants and Neuroprotection
  • Mycobacterium research and diagnosis
  • Nitrogen and Sulfur Effects on Brassica
  • Monoclonal and Polyclonal Antibodies Research
  • Plant Virus Research Studies
  • vaccines and immunoinformatics approaches
  • Pneumocystis jirovecii pneumonia detection and treatment
  • Influenza Virus Research Studies
  • Bacillus and Francisella bacterial research
  • Immunotherapy and Immune Responses
  • Advanced Drug Delivery Systems
  • Virus-based gene therapy research
  • Research in Cotton Cultivation
  • Infectious Diseases and Tuberculosis
  • Hepatitis B Virus Studies
  • Peptidase Inhibition and Analysis
  • RNA Interference and Gene Delivery
  • Poxvirus research and outbreaks
  • CRISPR and Genetic Engineering
  • Immune Response and Inflammation

Madurai Kamaraj University
2021-2024

Sathyabama Institute of Science and Technology
2024

Institute for Stem Cell Biology and Regenerative Medicine
2024

Genome editing techniques have transformed plant biotechnology allowing more precise and efficient alterations to genomes. These novel tools provide new chances for crop development, researchers build desired features in genetics. This study gives a complete summary of recent breakthroughs genome technologies, as well their uses future possibilities. The advancement artificial cleavage enzyme like Mega nuclease, ZFNs, TALENs, CRISPR/Cas9 has ushered era targeted modification plants. employ...

10.56557/pcbmb/2025/v26i3-49166 article EN cc-by PLANT CELL BIOTECHNOLOGY AND MOLECULAR BIOLOGY 2025-03-10

Mustard (Brassica species) plays a crucial role in global agriculture due to its high oil content and economic significance. However, challenges such as limited genetic diversity, disease susceptibility, environmental stressors hinder the potential of mustard crops. Genomic tools have emerged powerful enhance breeding by improving key traits yield, quality, resistance. Marker-Assisted Selection (MAS) has been widely applied select for desirable traits, including resistance, targeting...

10.9734/ijpss/2025/v37i35374 article EN International Journal of Plant & Soil Science 2025-04-02

Doubled haploid (DH) technology represents a major advancement in plant breeding, offering rapid and efficient method to produce completely homozygous lines single generation. This approach significantly shortens breeding cycles enhances genetic gain by accelerating the fixation of desirable traits. DH have become indispensable hybrid development, molecular quantitative trait loci (QTL) mapping, genomic selection, functional genomics. The encompasses both In vivo methods, such as inducer...

10.56557/pcbmb/2025/v26i7-89369 article EN PLANT CELL BIOTECHNOLOGY AND MOLECULAR BIOLOGY 2025-05-27

Tuberculosis (TB) is one of the major threats to public health; annually it kills more than 1.5 million people around globe. caused by an intracellular pathogen named Mycobacterium tuberculosis (Mtb). This Mtb enters lung through respiratory passage inhalation in healthy individuals. Infection this disease starts from settlement alveoli host external bacilli air droplets. After settlement, multiplication results induction innate immunity alveolar macrophages. Compared other infectious...

10.18006/2024.12(1).49.59 article EN Journal of Experimental Biology and Agricultural Sciences 2024-03-15

Globally, rising drug-resistant tuberculosis is a significant public health concern. Prompt diagnosis of and detection TB within clinically appropriate timeframe important for the effective management disease. Imaging approaches Chest X-rays, CT, MRI, nuclear medicine technique as PET/CT are non-specific, plays an role in assessment TB, but sometimes results false-positive or negative due to benign lesions.Currently using point care molecular modalities, Gene Xpert MTB/RIF line probe assays...

10.13005/bpj/2226 article EN Biomedical & Pharmacology Journal 2021-09-30

Abstract Background Vaccine development against tuberculosis remains a global health imperative, necessitating robust immunogenicity and safety profiles. Nanoparticle-based delivery systems offer promising avenues to enhance vaccine efficacy while ensuring tolerability. This study explores the utilization of chitosan micelles as platform for immune complex vaccination tuberculosis. Leveraging two key antigens Mycobacterium , namely HspX Mpt51, known their relevance in latent its co-infection...

10.1186/s43088-024-00520-x article EN cc-by Beni-Suef University Journal of Basic and Applied Sciences 2024-06-17
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