A5056558919- Genetic and phenotypic traits in livestock
- Animal Genetics and Reproduction
- Genetic Mapping and Diversity in Plants and Animals
- Chromosomal and Genetic Variations
- Neurological diseases and metabolism
- Mesenchymal stem cell research
- Meat and Animal Product Quality
- Molecular Biology Techniques and Applications
- Prion Diseases and Protein Misfolding
- CRISPR and Genetic Engineering
- dental development and anomalies
- Identification and Quantification in Food
- Parasite Biology and Host Interactions
- Vector-Borne Animal Diseases
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Biochemical Analysis and Sensing Techniques
- Amyotrophic Lateral Sclerosis Research
- Comparative Animal Anatomy Studies
- Regulation of Appetite and Obesity
- Pluripotent Stem Cells Research
- Veterinary Orthopedics and Neurology
- Trace Elements in Health
- T-cell and Retrovirus Studies
- Mollusks and Parasites Studies
- Eosinophilic Disorders and Syndromes
Universidad de la República de Uruguay
2008-2024
Universidad de Montevideo
2023
Universidad La República
2021
Universidad de la Empresa
2008
Universidad ORT Uruguay
2008
Universidad Autónoma Metropolitana
1991
ABSTRACT Background Familial narcolepsy in dogs has been associated with mutations the HCRTR2 gene Labrador retrievers, dachshunds, and Doberman pinschers, causal mutation differing between breeds. Objective To characterize genetic responsible for familial Dogo Argentino dogs. Animals Ten dogs, three narcoleptic seven clinically normal, of which four were related unrelated to Methods Case control prospective study. DNA was extracted from blood samples all Whole‐genome sequencing performed on...
Objectives The aim of this study was to isolate feline dental pulp stem cells (fDPSCs) and characterize their clonogenic proliferative abilities, as well multipotency, immunophenotype cytogenetic stability. Methods Dental isolated by explant culture from two cats <1 year old at post mortem. Their clonogenicity characterized using a colony-forming unit fibroblast assay, ability quantified with doubling time assay in passages 2, 4 6 (P 2 , P respectively). Multipotency an vitro trilineage...
Abstract The pampas deer belongs to the Cervidae family (Artiodactyla order). It used be a common and abundant species that had wide distribution. However, at end of 19th century, populations were decimated. In general, hearts mammals share many similarities, but size, shape, position, vessel organization branching can vary among species. objective present study was describe macroscopic morphology, topography irrigation heart deer. anatomical conducted with 20 animals died natural causes....
espanolEn Uruguay existe una reserva genetica de bovinos Criollos ubicada en el Departamento Rocha. Estudios previos basados marcadores moleculares altamente polimorficos mostraron que dicha poblacion presenta alta diversidad ge- netica. En la decada del 60 se produjo migra- cion a estable- cimientos ganaderos norte pais. Este gana- do fue utilizado cruzamientos comerciales con las razas Aberdeen Angus, Hereford, Caracu y cebuinas, estando sus productos introducidos mercado carnico uruguayo....
The widespread use of artificial insemination has allowed the expansion genetic progress. However, it also brought consequences such as lethal hereditary diseases and increase in inbreeding. object this study was to establish a fast sensitive molecular assay detect bovine leukocyte adhesion deficiency (BLAD) uridine monophosphate synthase (DUMPS) carriers Uruguayan Holstein cattle by means high resolution melting (HRM) curve analysis. By testing previously confirmed carrier non-carrier...
Prion diseases are fatal neurodegenerative disorders in which the main pathogenic event is conversion of cellular prion protein (PrPC) into an abnormal and misfolded isoform known as PrPSc. Most their susceptibility pathogenesis mainly modulated by PRNP gene that codes for PrP. Mutations polymorphisms can alter PrPC amino acid sequence, leading to a change transmission efficiency depending on place where it occurs. Horses animals considered be highly resistant prions. Several studies have...
El scrapie es una enfermedad neurodegenerativa transmisible de ovinos y caprinos.Se caracteriza por la acumulación en el sistema nervioso central isoforma anómala proteína celular normal (PrP c ) codificada gen PrP.En exón 2 del se han identificado mutaciones los codones 136, 154 171.La combinación estos muestran diferentes niveles asociación con susceptibilidad a enfermedad, desde muy resistentes (ARR/ ARR) susceptibles (VRQ/VRQ).Los 171 136 son mayores determinantes al scrapie, mientras...
Most dairy cattle breeds originate show an average generational inbreeding rate of 1%, which favors the occurrence recessive defects associated with low reproductive performance.The objective this study was to monitor performance in cattle.To bulls carrying Holstein Friesian haplotype (HH) 1, HH3, and HH4 haplotypes, we analyzed records 3,028 national imported from 2021 updated sires' catalog published by "Evaluaciones Genéticas Lecheras"; determine presence these mentioned as well Jersey...
Stem cell therapy in cat patients needs a high quantity of mesenchymal stromal/stem cells (MSCs) requiring vitro propagation under culture conditions which may potentially impact cellular characteristics and genetic stability. This study aimed to assess the cytogenetic stability adipose tissue-derived MSCs (cAT-MSCs). For this purpose, morphological features, clonogenic potential, proliferative capacity cAT-MSCs were assessed at passages 2 (P
Canine degenerative myelopathy (DM) is an autosomal recessive inherited disease that affects different dog breeds. It has invariably fatal outcome once the clinical symptoms begin. This study aimed to investigate population behavior of mutation superoxide dismutase 1 (SOD1) c.118: G>A responsible for high risk developing DM in two populations German Shepherd dogs from Uruguay and Paraguay. A total 158 (n = 114) Paraguay 44) were analyzed. Genomic DNA was extracted peripheral whole blood. The...
La reserva de bovinos Criollos del Uruguay (BCU) cuenta con aproximadamente 600 individuos. Estos animales han demostrado una elevada rusticidad y capacidad adaptación a medios poco favorables. En este trabajo se evaluó el crecimiento la producción carne 30 novillos en comparación 10 Hereford. Todos los recibieron mismo manejo sanitario alimentación (pastoreo campo natural, sin suplementación), desde 6-8 meses edad. A 43 seleccionó para faena muestra 6 evolución peso corporal fue similar,...
El scrapie es una enfermedad neuro-degenerativa transmisible de ovinos y caprinos. Se caracteriza por la acumulación en el sistema nervioso central isoforma anómala proteína celular normal (PrPc) codificada gen PrP. En exón 2 del se han identificado mutaciones los codones 136, 154 171. La combinación estos muestran diferentes niveles asociación con susceptibilidad a enfermedad, desde muy resistentes (ARR/ARR) susceptibles (VRQ/VRQ). Los 171 136 son mayores determinantes al scrapie, mientras...
ABSTRACT: Bovine spongiform encephalopathy (BSE) is a transmissible progressive neurodegenerative disease characterized by the accumulation of pathological isoform (PrpSC) cellular prion protein (PrpC) in brain cattle. Two insertion/deletion polymorphisms PRNP gene (23bp promoter and 12bp intron 1) have been associated with resistance or susceptibility to disease. The aim this study was analyze distribution these 214 healthy bovines belonging four different breed groups (Aberdeen Angus,...