A5035289941- Cancer Immunotherapy and Biomarkers
- Glioma Diagnosis and Treatment
- Neuroinflammation and Neurodegeneration Mechanisms
- Advanced Chemical Sensor Technologies
- Immune cells in cancer
- Spectroscopy and Chemometric Analyses
- Ovarian function and disorders
- Impact of Technology on Adolescents
- Alzheimer's disease research and treatments
- Ovarian cancer diagnosis and treatment
- MicroRNA in disease regulation
- Ectopic Pregnancy Diagnosis and Management
- Educational and Social Studies
- Wnt/β-catenin signaling in development and cancer
- Reproductive Biology and Fertility
- Ion Transport and Channel Regulation
- Barrier Structure and Function Studies
- Ion channel regulation and function
- Endometrial and Cervical Cancer Treatments
- Skin and Cellular Biology Research
- Cancer-related molecular mechanisms research
- RNA modifications and cancer
- Neuroblastoma Research and Treatments
- Immune responses and vaccinations
- Child Development and Digital Technology
Magna Graecia University
2013-2021
Azienda Ospedaliero Universitario Mater Domini
2015-2021
Sapienza University of Rome
2012-2020
Creative Research Enterprises (United States)
2016
Hôpital Pierre Wertheimer
2016
Hospices Civils de Lyon
2016
According to the Digital Agenda for Europe, way children use Internet and mobile technologies has changed dramatically in past years.The aims of this study were to: (1) breakdown modalities access by teenagers assess risks risky behaviors; (2) provide scientific data evaluate counsel safe new teenagers.The was conducted under program "Strategies a Better Children" started May 2012 European Commission. It represents main result project launched Telecom Italia, "Anche io ho qualcosa da dire"...
We report a case of woman with cryptic balanced translocation between chromosomes 5 and 17, suspected during genetic counseling. The had history previous fetal losses attributed to lissencephaly intra uterine growth retardation (IUGR) daughter dysmorphic features mental retardation, previously small deletion 5pter, detected years ago by first generation CGH-array. This peculiar combination personal family suggested the opportunity carry out FISH approach, focusing on based idea that...
Introduction: Magnetic resonance imaging (MRI) studies obtained during the initial staging of patients affected by uterine cervical cancer were compared to final histological report after surgery. Methods: Data retrieved from published papers. Results: MRI detection lymph node metastases shows a sensitivity 49.3% (1209 patients) and specificity 87.7% (1182 patients). Parametrial involvement has 66.2% (1288 83.6% (1282 tumor size evaluation significant error. Even over 1 cm diameter primary...
Objective . To assess aetiology of a POF in 33-year-old woman and, if possible, plan cure. Design Case report. Setting medical genetics diagnostic unit university hospital. Patient A with premature ovarian failure (POF). Intervention(s) Genetic counseling, karyotyping, FISH study. Result(s) Turner-like diagnosis. Conclusion(s) Most cases remain idiopathic. Turner syndrome can occur very different phenotypes; cytogenetic and molecular profiling provide definitive diagnosis nonclassical phenotype.
Gitelman's syndrome (GS) is a salt-losing tubulopathy with an autosomal recessive inheritance caused by mutations of SLC12A3 , which encodes for the thiazidesensitive NaCl cotransporter.In this study we report new mutation found in two brothers affected GS.Hypokalemia, hypocalciuria and hyperreninemia were present both patients while hypomagnesemia was detected only one.Both are compound heterozygotes carrying one well known GS associated (c.2581 C > T) (c.283delC) gene.The results possible...
The altered glucose metabolism characterising cancer cells determines an increased amount of methylglyoxal in their secretome. Previous studies have demonstrated that the methylglyoxal, turn, modifies protonation state (PS) soluble proteins contained secretomes cultivated circulating tumour (CTCs). In this study, we describe a method to assess content adducts (MAs) secretome by near-infrared (NIR) portable handheld spectroscopy and extreme learning machine (ELM) algorithm. By measuring...
Epidermolysis bullosa simplex is a disease that belongs to group of genodermatoses characterised by the formation superficial bullous lesions caused minor mechanical trauma skin. The skin fragility observed in EBS mainly pathogenic variants KRT5 and KRT14 genes compromise stability epithelial cells. By performing DNA sequencing female patient with EBS, we found variant c.967G>A (p.Val323Met) gene. This co-segregated family pedigree was transmitted an autosomal dominant inheritance manner....
<h3>Introduction</h3> Phenylketonuria (PKU MIM 261600) is a human metabolic disease caused by mutations in phenylalanine hydroxylase gene (PAH) and inherited an autosomal recessive Mendelian fashion. Phenylalanine (PAH also known as 4-monooxygenase EC 1,14,16,11) catalyzes the rate-limiting step L-Phenylalanine (L-Phe) catabolism liver, using tetrahydrobiopterin (BH<sub>4)</sub> dioxygen additional cosubstrates. Untreated PKU associated with abnormal phenotype which includes growth failure,...
<h3>Introduction</h3> The way children use the Internet and mobile technologies has changed in last few years according to Digital Agenda for Europe. growing phenomenon of cyberbullying is among risks associated with increasing use. Methods access by teenagers are highly important factors assessing those risks. <h3>Materials methods</h3> In order fight we have developed a strategy approval Department Medical Surgical Sciences Magna Graecia University Catanzaro consisting three phases: a)...