- Pregnancy and preeclampsia studies
- Pregnancy and Medication Impact
- Cardiovascular Issues in Pregnancy
- Assisted Reproductive Technology and Twin Pregnancy
- Gestational Diabetes Research and Management
- Maternal and fetal healthcare
- Antiplatelet Therapy and Cardiovascular Diseases
- Birth, Development, and Health
- Venous Thromboembolism Diagnosis and Management
- Pregnancy-related medical research
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Case Reports on Hematomas
- Blood Coagulation and Thrombosis Mechanisms
- Apelin-related biomedical research
- Ectopic Pregnancy Diagnosis and Management
Vrije Universiteit Amsterdam
2019-2025
Portal (Norway)
2025
Portál (Czechia)
2025
Amsterdam University Medical Centers
2019-2024
Amsterdam UMC Location Vrije Universiteit Amsterdam
2020-2023
Abstract Preeclampsia is a frequent gestational hypertensive disorder with equivocal pathophysiology. Knockout of peptide hormone ELABELA (ELA) has been shown to cause preeclampsia-like symptoms in mice. However, the role ELA human placentation and whether involved development preeclampsia humans not yet known. In this study, we show that exogenous administration able increase invasiveness extravillous trophoblasts vitro , change outgrowth morphology reduce trophoblast proliferation ex vivo...
To assess the added value of a novel, mobile educative application to standard counselling on aspirin adherence during pregnancy versus alone.
Objective To elucidate patients' knowledge and counseling perspective on aspirin reducing the risk of hypertensive disorders pregnancy (HDP).Methods A quantitative survey was performed including women who are members patient orgasnization Dutch HELLP Foundation due to a history HDP.Results Awareness risk-reducing effect HDP present in 51.9% 189 women. The majority informed by their gynecologist (89.8%) preferred be (79.4%), at postpartum checkup (42.3%) or consecutive (30.7%), both orally...
To evaluate the implementation of low-dose aspirin in pregnancy for prevention utero-placental complications among gynecologists Netherlands between 2016 and 2021. In this timeframe, a national guideline about was introduced by Dutch Society Obstetrics Gynecology.A online survey residents performed. An questionnaire distributed members Gynecology April Main outcome measure proportion indicating prescription high moderate risk indications.In 2016, 133 respondents completed survey, 2021 231....
1. Francis JH, Permezel M, Davey MA. Perinatal mortality by birthweight centile. Aust N Z J Obstet Gynaecol. 2014;54(4):354-359. doi:10.1111/ajo.12205 CrossRef Google Scholar
Blood pressure control in severe hypertension of pregnancy is crucial for mother and neonate. In absence evidence, guidelines recommend either intravenous labetalol or nicardipine. We compared the effectiveness safety these two drugs women with pregnancy.
Women with a multiple pregnancy are at increased risk of developing hypertensive disorders pregnancy. We describe case dichorionic triamniotic triplet complicated by severe hypertension, proteinuria and maternal symptoms, fitting the diagnosis pre-eclampsia, apart from early gestational age only 16 weeks. After reduction monochorionic pair, disease resolved pre-eclampsia was diagnosed again 30 weeks gestation, resulting in delivery on indication 33 gestation. In review literature, we found...