A5027899326- Orthopaedic implants and arthroplasty
- Bone Tissue Engineering Materials
- Total Knee Arthroplasty Outcomes
- Orthopedic Infections and Treatments
- Dental Implant Techniques and Outcomes
- Medical Malpractice and Liability Issues
- Advanced materials and composites
- Dental materials and restorations
- Advanced ceramic materials synthesis
- Spine and Intervertebral Disc Pathology
- Facial Trauma and Fracture Management
- Ethics in medical practice
- Healthcare cost, quality, practices
- Hip disorders and treatments
- Legal Education and Practice Innovations
- Knee injuries and reconstruction techniques
- Digital Imaging in Medicine
- Additive Manufacturing and 3D Printing Technologies
- Healthcare Policy and Management
- Calcium Carbonate Crystallization and Inhibition
- Osteoarthritis Treatment and Mechanisms
- Ethics in Clinical Research
- biodegradable polymer synthesis and properties
- Healthcare Quality and Management
- Pharmaceutical industry and healthcare
SINTX Technologies (United States)
2016-2025
Hartford Financial Services (United States)
2024-2025
Aetna (United States)
2024-2025
Government Medical College, Amritsar
2014-2021
Clinical Orthopaedics and Related Research
2018-2020
Tokyo Medical University
2020
University of Missouri
2010-2019
Singapore General Hospital
2019
University of Missouri Health System
2010-2018
Salt Lake Regional Medical Center
2018
The most commonly used bearing couple in prosthetic hip or knee joint replacements consists of a cobalt–chrome (CoCr) metal alloy articulating against ultrahigh‐molecular‐weight polyethylene. Ceramics have been as an alternative to metal‐on‐polyethylene replacement surgery arthritic hips and knees since the 1970s. In bearings, ceramic surfaces offer major benefit drastically reduced wear rates excellent long‐term biocompatibility, which can increase longevity joints. This is important...
Medical malpractice law in the United States is derived from English common law, and was developed by rulings various state courts. lawsuits are a relatively occurrence States. The legal system designed to encourage extensive discovery negotiations between adversarial parties with goal of resolving dispute without going jury trial. injured patient must show that physician acted negligently rendering care, such negligence resulted injury. To do so, four elements be proven: (1) professional...
Calcium binding properties of bone acidic glycoprotein-75, osteopontin, and sialoprotein were determined in 10 mM imidazole buffer (pH 6.8), containing either 60 KCl or 150 NaCl. Proteins assayed first bound to nitrocellulose mimic substrate-bound forms vivo; retention phosphoproteins was through use radioiodinated tracers. Binding studies carried out both as a function calcium concentration the amount phosphoprotein. In presence KCl, glycoprotein-75 exhibited largest capacity (139...
Abstract Glasses containing varying amounts of B 2 O 3 were prepared by partially or fully replacing the SiO in silicate 45S5 bioactive glass with . The effects content on its conversion to hydroxyapatite (HA) and proliferation MC3T3‐E1 cells investigated vitro Conversion glasses HA dilute (20 m M ) K HPO 4 solution was monitored using weight loss pH measurements. Proliferation determined qualitatively assay cell density at interface after incubation for 1 day days, quantitatively...
In Part I, the in vitro degradation of bioactivAR52115e glass scaffolds with a microstructure similar to that human trabecular bone, but three different compositions, was investigated as function immersion time simulated body fluid. The glasses consisted silicate (13-93) composition, borosilicate composition (designated 13-93B1), and borate (13-93B3), which one-third or all SiO2 content 13-93 replaced by B2O3, respectively. This work is an extension investigate effect on response osteogenic...
Total hip replacement performed through a small incision theoretically results in less trauma to the underlying structures, reduced blood loss, pain, and shorter hospital stay, but it may result increased complications, particularly early surgeon's experience with new technique. In present study, we reviewed of two techniques involving use smaller incisions; specifically, evaluated one series primary total replacements that had been incisions another single incision.Eighty-nine consecutive...
Abstract Freeze casting of aqueous suspensions on a cold substrate was investigated as method for preparing hydroxyapatite (HA) scaffolds with unidirectional porosity. In the present paper, we report ability to manipulate microstructure freeze‐cast constructs by controlling processing parameters. Constructs prepared from (5–20 volume percent particles) steel at −20°C had lamellar‐type microstructure, consisting plate‐like HA and pores oriented in direction freezing. Sintering 3 h 1350°C...
Abstract: A significant need exists for orthopedic implants that can intrinsically resist bacterial colonization. In this study, three biomaterials are used in spinal – titanium (Ti), poly-ether-ether-ketone (PEEK), and silicon nitride (Si 3 N 4 ) were tested to understand their respective susceptibility infection with Staphylococcus epidermidis , Staphlococcus aureus Pseudomonas aeruginosa Escherichia coli Enterococcus . Specifically, the surface chemistry, wettability, nanostructured...
Abstract While the reciprocity between bioceramics and living cells is complex, it principally governed by implant’s surface chemistry. Consequently, a deeper understanding of chemical interactions with tissue could ultimately lead to new therapeutic strategies. However, physical principles that govern these remain unclear. The intricacies this biological synergy are explored within paper examining peculiar chemistry relatively bioceramic, silicon nitride (Si 3 N 4 ). Building upon prior...
Abstract The silicate‐based 45S5 bioactive glass, typically in particulate form, has been widely investigated for bone repair. However, its application as a scaffold tissue engineering is limited due to the difficulty of forming porous three‐dimensional constructs with complex shapes. In this study, use another referred 13–93, was preparation constructs. Particles 13–93 glass (255–325 μm) were consolidated and sintered form cylindrical Characterization these performed using mercury...
Organisms of Gram-negative phylum bacteroidetes, Porphyromonas gingivalis, underwent lysis on polished surfaces silicon nitride (Si3N4) bioceramics. The antibacterial activity Si3N4 was mainly the result chemically driven principles. lytic activity, although not osmotic in nature, related to peculiar pH-dependent surface chemistry Si3N4. A buffering effect via formation ammonium ions (NH4(+)) (and their modifications) experimentally observed by pH microscopy. Lysis confirmed conventional...