- Reproductive Biology and Fertility
- Sperm and Testicular Function
- Bee Products Chemical Analysis
- Acute Myeloid Leukemia Research
- Bone fractures and treatments
- Tissue Engineering and Regenerative Medicine
- Anesthesia and Pain Management
- Orthopaedic implants and arthroplasty
- Blood disorders and treatments
- Healthcare and Venom Research
- Orthopedic Infections and Treatments
- Essential Oils and Antimicrobial Activity
- Testicular diseases and treatments
- Periodontal Regeneration and Treatments
- Reproductive Health and Technologies
- Animal Genetics and Reproduction
- Acute Lymphoblastic Leukemia research
- Pluripotent Stem Cells Research
- Mitochondrial Function and Pathology
- Anesthesia and Neurotoxicity Research
- Bone health and treatments
- Intestinal and Peritoneal Adhesions
- Complementary and Alternative Medicine Studies
- Neutropenia and Cancer Infections
- Knee injuries and reconstruction techniques
Ankara University
2014-2025
Turkish Society of Hematology
2008
Ministry of Health
1999-2008
Ufuk University
2007-2008
Ulucanlar Göz Eğitim ve Araştırma Hastanesi
2008
Bursa Uludağ Üni̇versi̇tesi̇
2003
Hacettepe University
2003
Kırıkkale University
2000
Committee on Publication Ethics
1999
Temporoparietal fascia constitutes a very important structural unit from both an aesthetic and reconstructive surgical point of view. A histologically supported anatomic study was conducted for the reappraisal relationships clinical application potentials data obtained. Anatomy temporoparietal investigated on 20 sides 10 cadavers. After dissections, necropsies were obtained to demonstrate histologic features fascia. The outer part is continuous with superficial musculoaponeurotic system...
Several recent reports proposed that astrocyte death might precede neuronal demise after focal ischemia, contrary to the conventional view astrocytes are more resistant injury than neurons. Interestingly, there findings supporting each of these opposing views. To clarify controversies, we assessed viability 2-h middle cerebral artery occlusion in mice. In contrast neighboring neurons, were alive and contained glycogen across ischemic area 6 h reperfusion, at expanding outer border infarct...
Abstract It has been previously demonstrated that human umbilical cord stroma-derived stem cells (HUCSCs) are competent to differentiate into adipocytes. However, controversies have arisen as whether HUCSCs can become mature adipocytes or not, and what extent these be induced in adipogenic pathway. Here, we extensively analyzed their potency with a structural functional approach by determining lipid formation dynamics concordance adipocyte-specific markers. During 35-day period, respond...
The role of high mobility group box 1 (HMGB1) in inflammation is well characterized the immune system and response to tissue injury. More recently, HMGB1 was also shown initiate an "inflammatory signaling cascade" brain parenchyma after a mild brief disturbance, such as cortical spreading depolarization (CSD), leading headache. Despite substantial evidence implying for inflammatory prevalent neuropsychiatric disorders migraine depression, how released from healthy neurons initiated absence...
Cartilage defects are a source of pain, immobility, and reduced quality life for patients who have acquired these through injury, wear, or disease. The avascular nature cartilage tissue adds to the complexity repair regeneration efforts. known limitations using autografts, allografts, xenografts further add this complexity. Autologous chondrocyte implantation matrix-assisted techniques attempt introduce cultured cells defect areas in patient, but clinical success with impeded by avascularity...
Transcriptomics of atrial fibrillation (AFib) in the setting chronic primary mitral regurgitation (MR) remains to be characterized. We aimed compare gene expression profiles patients with degenerative MR AFib and sinus rhythm (SR) for a clearer picture pathophysiology. After transcriptomic analysis bioinformatics (n = 59), differentially expressed genes were defined using 1.5-fold change as threshold. Additionally, independent datasets from GEO included meta-analyses. QRT-PCR confirmed that...
Liver ischemia reperfusion injury (IRI) is an important pathologic process leading to bodily systemic effects and liver injury. Our study aimed investigate the protective of diosmin, a phlebotrophic drug with antioxidant anti-inflammatory effects, in IRI model. Forty rats were divided into 4 groups. Sham group, control group (ischemia-reperfusion), intraoperative treatment preoperative group. Ischemia model was formed by clamping hepatic pedicle for 60 minute followed another 90 minutes....
Background: Observations in humans and animal models have shown that statins, besides reducing cholesterol levels ischemic heart disease, might also reduce the risk of osteoporotic fractures. The purpose this study was to investigate effects simvastatin on fracture healing vivo. Materials: Fifty-four rats were randomly assigned one three groups: control group groups with two doses 1 mg/d 2 drug injected. We performed a closed by digital manipulation distal leg healthy under ketamine...
Pregnancy achieved with sperm from a patient globozoospermia is rare, even after ICSI, since the activation of oocyte may not occur in this disorder. Therefore, oocytes by piezoelectricity or calcium ionophores has been suggested, although spontaneous ICSI reported some cases. We report successful pregnancy couple which male partner had microdeletions Y chromosome no further assisted ICSI. During diagnostic study husband, increased numerical abnormalities fluorescent in-situ hybridization...
AIM:To evaluate the effects of honey on bacterial translocation and intestinal villus histopathology in experimental obstructive jaundice.METHODS: Thirty Wistar-Albino rats were randomly divided into three groups each including 10 animals: group Ⅰ, sham-operated; Ⅱ, ligation section common bile duct (BDL); Ⅲ, followed by oral supplementation (BDL + honey) g/kg per day.Liver, blood, spleen, mesenteric lymph nodes, ileal samples taken for microbiological, light transmission electrone...
We have previously demonstrated that various subtypes of AML children respond to high-dose methylprednisolone (HDMP; 20-30 mg/kg/day) which could induce in vivo differentiation myeloid leukemic cells mature granulocytes. In this study we evaluated whether apoptosis occurs patients treated by HDMP using morphological criteria. For light and electron microscopic examination bone marrow aspirates were obtained four days two weeks after (30 treatment from with newly diagnosed (AML-M3 AML-M4)....
To evaluate the effect of propolis administration on healing colon anastomosis with light and transmission electron microscopes.Forty-eight Wistar-Albino female rats were divided into two groups had resection anastomosis. In group I, fed standard rat chow pre- postoperatively. The in II began receiving oral supplementation 100 mg/kg per day beginning 7 d before operation continued until they sacrificed. Rats sacrificed 1, 3, 14 after operation, anastomotic bursting pressures measured. After...