A5019375661- Animal Disease Management and Epidemiology
- Vector-Borne Animal Diseases
- Viral Infections and Immunology Research
- Animal Virus Infections Studies
- Virus-based gene therapy research
- Viral gastroenteritis research and epidemiology
- T-cell and Retrovirus Studies
- Parvovirus B19 Infection Studies
- Congenital Anomalies and Fetal Surgery
- Influenza Virus Research Studies
- Herpesvirus Infections and Treatments
- Viral Infections and Vectors
- Plant Virus Research Studies
- SARS-CoV-2 and COVID-19 Research
- Infection Control and Ventilation
- Mosquito-borne diseases and control
- Rabies epidemiology and control
- Virology and Viral Diseases
- Bacillus and Francisella bacterial research
- RNA modifications and cancer
- Microbial infections and disease research
- Hepatitis C virus research
- Infectious Diseases and Mycology
- Respiratory viral infections research
- Spinal Dysraphism and Malformations
Universidade Federal do Rio Grande do Sul
2015-2024
Agricultural Research Service
2020-2023
National Animal Disease Center
2020-2023
Universidade Feevale
2022
Universidade Federal da Paraíba
2020
Secretaria de Agricultura e Abastecimento
2020
The genus Pestivirus of the family Flaviviridae consists four recognized species: Bovine viral diarrhoea virus 1 (BVDV-1), 2 (BVDV-2), Classical swine fever (CSFV) and Border disease (BDV). Recently, atypical pestiviruses ('HoBi'-like pestiviruses) were identified in batches contaminated foetal calf serum naturally infected cattle with without clinical symptoms. Here, we describe first report a mucosal disease-like presentation (MD) associated 'HoBi'-like pestivirus occurring herd. outbreak...
Pestivirus infections in ruminants result significant economic losses worldwide. The aetiological agents are three species from the genus Pestivirus, family Flaviviridae, including bovine viral diarrhoea virus type 1 (BVDV-1), BVDV-2, border disease (BDV), and an atypical pestivirus named HoBi-like pestivirus. In this study, eighty-nine isolates that were collected Brazil between 1995 2014 originated either cattle, fetal serum (FBS) or as cell culture contaminants genotyped based on a...
Recently, a putative new pestivirus species, provisionally named as Atypical Porcine Pestivirus (APPV), was associated with the congenital tremor in piglets North America and consequently Europe Asia. The present research aimed to describe detection characterization of APPV employing NS5B gene partial sequencing, gross pathology histologic examination displaying from two different farms Southern Brazil. No lesions were observed, histological findings revealed moderate vacuolization white...
Ruminant pestiviruses can infect cattle populations worldwide and cause significant economic losses due to their impact on productivity health. Knowledge of pestivirus diversity is important for control programs vaccine development determining probable sources infection. In this paper, we describe a search ruminant with RT-PCR in sera 9078 calves from 6 12 months age. The were first analyzed pools then individually. Thirty-three positive animals detected (0.36%) 6.9% (24) the 346 herds....
Viruses from the genus Pestivirus of family Flaviviridae have a non-segmented, single-stranded RNA genome and can cause diseases in animals order Artiodactyla. Homologous recombination is rarely reported this virus family. To detect possible events, all complete pestivirus genomes that are available GenBank were screened using distinct algorithms to genetic conversions incongruent phylogenies. Three putative recombinant viruses derived different subtypes/genogroups detected: Bovine viral...
Bovine viral diarrhea virus (BVDV) belongs to the Pestivirus genus, which is further divided into subgenotypes (1a–1u and 2a–c). When persistent infection occurs, calf will be immunotolerant BVDV possibly develop mucosal disease. This study describes an outbreak of BVDV-1d–induced disease lacking intestinal lesions. Eleven calves presented with anorexia, sialorrhea, lameness, recumbency, death. Three were necropsied, showing ulceration interdigital skin oral nasal mucosa; linear ulcers in...
The ruminant pestiviral species BVDV-1, BVDV-2 and BDV, along with the putative HoBi-like, may cause substantial economic losses in cattle, sheep goats. Brazil's large size, variable biomes wide range of animal production within different geographic regions suggest that presence prevalence pestivirus differ by Brazil. This study investigated genetic diversity pestiviruses determined frequency active infections two states Northeast Region Brazil, Maranhão Rio Grande do Norte. Serum samples...
Bovine viral diarrhea virus (BVDV) is comprised of two species, BVDV-1 and BVDV-2, but given the genetic diversity among pestiviruses, at least 21 subgenotypes are described for 4 BVDV-2. Genetic characterization can be achieved through complete or partial sequencing phylogeny, antigenic difficult to determine due cross-neutralization that exists isolates. The traditional method evaluating relationships between pestivirus isolates neutralization (VN) assay, interpretation data difference...
Brazil is a major exporter of pork meat worldwide. Swine liver common ingredient in food consumed by humans, thus emphasizing the importance evaluating presence associated pathogens swine liver. To obtain knowledge, this study aimed to provide insights into viral communities livers collected from slaughtered pigs southern Brazil. The 46 were processed and submitted for high-throughput sequencing (HTS). sequences most closely related Anelloviridae, Circoviridae Parvoviridae families. present...
Hepatitis E virus (HEV) is the causative agent of acute hepatitis worldwide. There no seroprevalence study in backyard farms, which are characterized by suboptimal hygienic conditions Brazil. We aimed to determine and genetic diversity HEV pigs Swine serum samples collected 2012 (n=731) 2014 (n=713) were analysed. The presence anti-HEV immunoglobulin G pig was evaluated indirect enzyme-linked immunosorbent assay. Reverse transcription polymerase chain reaction performed phylogenetic analyses...
The HoBi-like pestivirus (HoBiPeV), currently classified as Pestivirus H species, is a pathogen associated with broad spectrum of clinical manifestations in ruminants, particularly cattle. Since HoBiPeV complete genome sequencing data scarce, the present study we described five nearly new Brazilian genomes and further perform more genetic evolutionary characterization all additional sequences available GenBank database. Entropy selection pressure analysis showed E2 gene, surface...
The Pestivirus genus comprises species that affect animal health and productivity worldwide. Members of the Suidae family are hosts for classical swine fever virus (CSFV), an important pathogen tracked by World Organization Animal Health (OIE). However, also susceptible to other pestivirus can result in disease or compromise CSFV detection. We searched infection sera collected from 320 backyard pig herds southern Brazil. used reverse-transcription PCR primers Bungowannah virus; atypical...
Pestiviruses are globally distributed and cause substantial economic losses to the cattle industry. In Brazil, country with world’s largest population, pestivirus infections well described in some regions, such as south, where a high frequency of BVDV-2 is contrasts prevalence HoBi-like (HoBiPeV) northeast. However, there lack information about pestiviruses Amazon Region, northern population estimated at 55.7 million head, which has significant impact on international livestock market....
Hepaciviruses (HVs) have been detected in several domestic and wild animals present high genetic diversity. The actual classification divides the genus Hepacivirus into 14 species (A-N), according to their phylogenetic relationships, including bovine hepacivirus [Hepacivirus N (HNV)]. In this study, we confirmed HNV circulation Brazil sequenced whole genome of two strains. Based on current HCV, which is divided genotypes subtypes, analysed all available sequences GenBank database proposed an...