A5023734827- Trace Elements in Health
- Biochemical Acid Research Studies
- Metal complexes synthesis and properties
- Drug Transport and Resistance Mechanisms
- Glutathione Transferases and Polymorphisms
- Metabolomics and Mass Spectrometry Studies
- Free Radicals and Antioxidants
- Lymphoma Diagnosis and Treatment
- DNA Repair Mechanisms
- Renal and related cancers
- Drug-Induced Hepatotoxicity and Protection
- Acute Kidney Injury Research
- Sulfur Compounds in Biology
- Viral-associated cancers and disorders
- Electron Spin Resonance Studies
- Renal cell carcinoma treatment
- Iron Metabolism and Disorders
- CRISPR and Genetic Engineering
- Hemoglobinopathies and Related Disorders
- Genomics and Chromatin Dynamics
- Diet, Metabolism, and Disease
- Cardiac Ischemia and Reperfusion
- Immune Cell Function and Interaction
- Hemoglobin structure and function
- Nitric Oxide and Endothelin Effects
Okayama University of Science
2004-2022
Okayama University
1990-2003
Okayama Prefectural University
1998
Utano Hospital
1996
University of California, Berkeley
1994-1996
BioEnergetics (United States)
1994
Isolated haemosiderin contained iron and nitrogen in a weight ratio of 6.75, with phosphorus no detectable haem. Considerably more was released from under acidic conditions than neutral the presence ascorbate, nitrilotriacetate or dithionite. Unlike situation chelators such as citrate, ADP succinate induced release only some iron, almost pH-dependence. Dehydroascorbate (the oxidized form ascorbate reducing capacity) behaved like ADP, desferal, rather itself, releasing iron. GSH had less...
Redox-active iron was demonstrated in mouse kidney by Timm's sulphide-silver staining after an injection of a renal carcinogen, iron-nitrilotriacetate (Fe-NTA). The on the apical site tubular epithelia proximal convoluted portion and tubules straight 30 min Fe-NTA injection. As epithelial cells died, disappeared dead stored cytoplasm more distal epithelia. Biochemically, redox-active rapidly increased to four times higher than control injection, then decreased plateau which still control....
The copper and Iron status in the liver of non‐tumor bearing Long‐Evans Cinnamon (LEC) rats (average age 17 months) was investigated. A direct quantitation loosely‐bound iron also investigated by using a chelating agent, nitrilotriacetic acid (NTA‐chelatable free iron). Besides total contents, level NTA‐chelatable higher LEC than In LEA (P<0.05). But for there no signiflcant difference between two rat groups (P>0.05). formation thiobarbituric acid‐reactive substances (P<0.01)....
The purpose of this study was to investigate the relationship between local immune response, clinicopathological variables and prognosis in esophageal squamous cell carcinoma (SCC). A total 377 cases SCC without preoperative radiotherapy, chemotherapy or immunotherapy were studied. Corrected 5‐year survival for pronounced, moderate sparse immunocyte infiltration 66%, 43% 24%, respectively. In multivariate analysis, an independent prognostic factor (p<0.001). correlation found density...
Iron-induced free radical injuries in male and female ddY mice, especially the sex difference its mechanisms, were studied after an i.p. injection of a renal carcinogen, ferric nitrilotriacetate. Male mice much more susceptible to iron-induced than mice. Oxidative modification proteins DNA occurred strongly males females, as measured by protein carbonyl content 8-hydroxydeoxyguanosine, respectively. Histochemical detection 4-hydroxy-2-nonenal-modified using antibody fragmentation detected...