A5067843383- 3D Printing in Biomedical Research
- Innovative Microfluidic and Catalytic Techniques Innovation
- Additive Manufacturing and 3D Printing Technologies
- Analytical Chemistry and Sensors
- Electrochemical sensors and biosensors
- Graphene and Nanomaterials Applications
- Biomedical Text Mining and Ontologies
- Advanced Materials and Mechanics
- Advanced Sensor and Energy Harvesting Materials
- Cell Image Analysis Techniques
- Micro and Nano Robotics
- Biosensors and Analytical Detection
- Microfluidic and Capillary Electrophoresis Applications
- Characterization and Applications of Magnetic Nanoparticles
- Pickering emulsions and particle stabilization
- 2D Materials and Applications
- bioluminescence and chemiluminescence research
- Nanoplatforms for cancer theranostics
- MXene and MAX Phase Materials
- Graphene research and applications
- Bone Tissue Engineering Materials
- Neuroscience and Neural Engineering
Texas A&M University
2015-2024
Mitchell Institute
2019-2021
College Station Medical Center
2019
Two-dimensional (2D) nanomaterials are ultrathin with a high degree of anisotropy and chemical functionality. Research on 2D is still in its infancy, the majority research focusing elucidating unique material characteristics few reports biomedical applications nanomaterials. Nevertheless, recent rapid advances have raised important exciting questions about their interactions biological moieties. nanoparticles such as carbon-based materials, silicate clays, transition metal dichalcogenides...
Clickable poly(ethylene glycol) hydrogel microspheres can be 3D printed and photochemically annealed to produce complex cell-laden structures.
We introduce an enhanced nanoengineered ionic-covalent entanglement (NICE) bioink for the fabrication of mechanically stiff and elastomeric 3D biostructures. NICE formulations combine nanocomposite (ICE) strengthening mechanisms to print customizable cell-laden constructs tissue engineering with high structural fidelity mechanical stiffness. Nanocomposite ICE complement each other through synergistic interactions, improving strength, elasticity, toughness, flow properties beyond sum effects...
Bioprinting is an emerging additive manufacturing approach to the fabrication of patient-specific, implantable three-dimensional (3D) constructs for regenerative medicine. However, developing cell-compatible bioinks with high printability, structural stability, biodegradability, and bioactive characteristics still a primary challenge translating 3D bioprinting technology preclinical clinal models. To overcome this challenge, we developed nanoengineered ionic covalent entanglement (NICE)...
Bioprinting hydrogel microparticles requires consideration of size, stiffness, and nozzle geometry due to jamming effects.
3D bioprinting has revolutionized tissue engineering by enabling researchers to create much more complex structures than was practical with earlier techniques. Bioprinting uses computer-controlled layer-by-layer deposition of a mixture hydrogels and living cells the resulting can mimic geometries many tissues incorporating multiple bioinks varied material properties cell populations, allowing design that vary not only in shape, but also mechanical, chemical, biological throughout bioprinted...
Abstract Additive manufacturing is a promising method for producing customized 3D bioactive constructs regenerative medicine. Here, printed highly osteogenic scaffolds using nanoengineered ionic–covalent entanglement ink (NICE) bone tissue engineering are reported. This NICE consists of reinforced with Laponite, 2D nanosilicate (nSi) clay, allowing the printing anatomic‐sized high accuracy. The structure able to maintain structural stability in physiological conditions without any...
Insertable biosensor systems are medical diagnostic devices with two primary components: an implantable within the body and a wearable monitor that can remotely interrogate from outside body. Because does not require physical connection to electronic monitor, insertable promise improved patient comfort, reduced inflammation infection risk, extended operational lifetimes relative established percutaneous systems. However, lack of also presents technical challenges have necessitated new...
ABSTRACT Chronic diseases including diabetes, cardiovascular diseases, and microvascular complications contribute significantly to global morbidity mortality. Multiplexing technologies offer a promising approach for the simultaneous detection management of comorbidities, providing comprehensive disease insights. In this work, we describe miniaturized optical “barcode” sensor with high biocompatibility continuous monitoring glucose oxygen. This enzymatic relies on oxygen consumption in...
For the past decade, additive manufacturing has resulted in significant advances toward fabricating anatomic-size patient-specific scaffolds for tissue models and regenerative medicine. This can be attributed to development of advanced bioinks capable precise deposition cells biomaterials. The combination with is enabling researchers fabricate intricate that recreate complex spatial distributions bioactive cues found human body. However, expansion this promising technique been hampered by...
Chronic diseases, including diabetes, cardiovascular and microvascular complications, contribute significantly to global morbidity mortality. Current monitoring tools such as glucometers continuous glucose monitors only measure one analyte; multiplexing technologies offer a promising approach for multiple biomarkers, enabling the management of comorbidities providing more comprehensive disease insights. In this work, we describe miniaturized optical "barcode" sensor with high...
Phosphorescence-based oxygen-sensing hydrogels are a promising platform technology for an upcoming generation of insertable biosensors that smaller, softer, and potentially more biocompatible than earlier designs. However, much remains unknown about their long-term performance biocompatibility in vivo. In this paper, we design evaluate range hydrogel sensors contain oxygen-sensitive phosphors stabilized by micro- nanocarrier systems. These devices demonstrated consistently good young adult...
Interactions between active individuals in animal collectives lead to emergent responses that remain elusive synthetic soft matter. Here, shape-morphing polymers are used create bio-inspired transient solids self-assemble with controlled mechanical properties and disassemble on demand. Dilute-suspensions of magnetic, heat-responsive liquid crystal elastomer ribbons mechanically interlock, inducing reversible aggregation. A mathematical model is developed sheds light the role topological...
Abstract Over the past decade, additive manufacturing has resulted in significant advances towards fabricating anatomic-size, patient-specific scaffolds for tissue models and regenerative medicine. This can be attributed to development of advanced bioinks capable precise deposition cells biomaterials. The combination with is enabling researchers fabricate intricate that recreate complex spatial distributions bioactive cues found human body. However, expansion this promising technique been...
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