André Ohara

ORCID: 0000-0002-9792-284X
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About
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Research Areas
  • Biofuel production and bioconversion
  • Enzyme Production and Characterization
  • Protein Hydrolysis and Bioactive Peptides
  • Enzyme Catalysis and Immobilization
  • Diatoms and Algae Research
  • Microbial Metabolites in Food Biotechnology
  • Fungal and yeast genetics research
  • Food Quality and Safety Studies
  • Insect Utilization and Effects
  • Fungal Biology and Applications
  • Plant Pathogens and Fungal Diseases
  • Glycosylation and Glycoproteins Research
  • Carbohydrate Chemistry and Synthesis
  • Tannin, Tannase and Anticancer Activities
  • Protist diversity and phylogeny
  • biodegradable polymer synthesis and properties
  • Microbial Metabolic Engineering and Bioproduction
  • Meat and Animal Product Quality
  • Folate and B Vitamins Research
  • Plant tissue culture and regeneration
  • Microbial Natural Products and Biosynthesis
  • Microencapsulation and Drying Processes
  • Electrospun Nanofibers in Biomedical Applications
  • Plant and fungal interactions
  • Microbial Metabolism and Applications

Imperial College London
2024

Technische Universität Dresden
2020-2022

Universidade Estadual de Campinas (UNICAMP)
2014-2021

Hokkaido University
2017-2018

SUMMARY Morphogenesis of the intricate patterns diatom silica cell walls is a protein‐guided process, yet to date only very few such biomineralization proteins have been identified. Therefore, it currently unknown whether all diatoms share conserved basal forming machinery, and unique are responsible for morphogenesis species‐specific patterns. To answer these questions, we extracted from three species ( Thalassiosira pseudonana , oceanica Cyclotella cryptica ) by complete demineralization...

10.1111/tpj.15765 article EN cc-by The Plant Journal 2022-04-11

Bioactive peptides are fragments of polypeptide chains with specific sequence amino acids that can promote positive effects on human health. A potential substrate to obtaining these compounds is the common bean (Phaseolus vulgaris L. cv Carioca) due its high protein content. In this sense, objective study was evaluate antioxidant and antidiabetic properties hydrolysates. The proteases Flavourzyme™ 500L, Alcalase™ 2.4 L Neutrase™ 0.8 were applied individually in binary/ternary combinations,...

10.1080/10242422.2020.1789114 article EN Biocatalysis and Biotransformation 2020-07-06

This study reports the use of statistical mixture design as a tool for simultaneous production lipase, CMCase, α-amylase, and β-glucosidase by Aspergillus niger under solid-state fermentation. Wheat bran, soybean meal, cottonseed orange peel were used substrates, either individually or combined in different formulations, to their synergistic antagonistic effects on enzymes. The highest lipase (323 U g-1) CMCase (10 activities detected after 48 h, while maximum α-amylase (18 (15 occurred at...

10.1590/1678-457x.17017 article EN Food Science and Technology 2018-01-13

Screening of new microbial strains for enzyme production is a key step in the improvement industrial bioprocesses. The objective this work was to isolate fungal from Brazilian rainforests and evaluate their potential produce enzymes by solid state fermentation. First, 131 filamentous fungi were isolated Amazon rainforest Atlantic regions. Strains selected simple plate assay had ability lipase tannase fermentation wheat bran evaluated. Maximum enzymatic activity 1.35 18.7 U/mL reached...

10.5897/ajmr2014.7234 article EN African Journal of Microbiology Research 2015-02-04

Correct elaboration of N-linked glycans in the secretory pathway human cells is essential physiology. Early N-glycan biosynthesis follows an assembly line principle before undergoing crucial points that feature sequential incorporation sugar N-acetylglucosamine (GlcNAc). The activity GlcNAc transferase V (MGAT5) primes antenna heavily upregulated cancer. Yet, functional relevance and substrate choice MGAT5 are ill-defined. Here, we employ a tactic termed bump-and-hole engineering to develop...

10.26434/chemrxiv-2024-856gt preprint EN 2024-05-02

Correct elaboration of N-linked glycans in the secretory pathway human cells is essential physiology. Early N-glycan biosynthesis follows an assembly line principle before undergoing crucial points that feature sequential incorporation sugar

10.1021/jacs.4c05955 article EN cc-by Journal of the American Chemical Society 2024-09-17

Summary Morphogenesis of the intricate patterns diatom silica cell walls is a protein-guided process, yet to date only very few such morphogenetic proteins have been identified. Therefore, it unknown whether all diatoms share conserved basal forming machinery, and unique are responsible for morphogenesis species specific patterns. To answer these questions, we extracted from three ( Thalassiosira pseudonana, oceanica Cyclotella cryptica ) by complete demineralization walls. LC-MS/MS analysis...

10.1101/2021.09.18.460806 preprint EN bioRxiv (Cold Spring Harbor Laboratory) 2021-09-19
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