Ladan Kashani

ORCID: 0000-0002-9832-5625
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About
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Research Areas
  • Ovarian function and disorders
  • Endometriosis Research and Treatment
  • Reproductive Biology and Fertility
  • Saffron Plant Research Studies
  • Reproductive System and Pregnancy
  • Menstrual Health and Disorders
  • Maternal Mental Health During Pregnancy and Postpartum
  • Menopause: Health Impacts and Treatments
  • Schizophrenia research and treatment
  • Complementary and Alternative Medicine Studies
  • Assisted Reproductive Technology and Twin Pregnancy
  • Uterine Myomas and Treatments
  • Pharmacology and Obesity Treatment
  • Gynecological conditions and treatments
  • Tryptophan and brain disorders
  • Endometrial and Cervical Cancer Treatments
  • Hedgehog Signaling Pathway Studies
  • Reproductive Health and Technologies
  • Neurotransmitter Receptor Influence on Behavior
  • Health and Well-being Studies
  • Medicinal Plant Extracts Effects
  • Healthcare and Venom Research
  • Estrogen and related hormone effects
  • Acupuncture Treatment Research Studies
  • Therapeutic Uses of Natural Elements

Tehran University of Medical Sciences
2016-2025

Health First
2022

Iran University of Medical Sciences
2022

Roointan Arash Hospital
2017-2021

Royan Institute
2020

University of Tehran
2007-2019

Shariati Hospital
2007-2010

Imam Khomeini Hospital
2005

Roozbeh Hospital
2002

Objective The aim of this double‐blind and placebo‐controlled trial was to investigate whether saffron (stigma Crocus sativus L.) could relieve symptoms premenstrual syndrome (PMS). Design Double‐blind, randomised trial. Setting Departments Gynaecology/Obstetrics Psychiatry, Tehran Zanjan University Medical Sciences. Population Women aged 20–45 years with regular menstrual cycles experience PMS for at least 6 months were eligible the study. Method randomly assigned receive capsule 30 mg/day...

10.1111/j.1471-0528.2007.01652.x article EN BJOG An International Journal of Obstetrics & Gynaecology 2008-02-06

Objective Saffron ( Crocus sativus L.) has shown beneficial aphrodisiac effects in some animal and human studies. The aim of the present study was to assess safety efficacy saffron on selective serotonin reuptake inhibitor‐induced sexual dysfunction women. Methods This a randomized double‐blind placebo‐controlled study. Thirty‐eight women with major depression who were stabilized fluoxetine 40 mg/day for minimum 6 weeks had experienced subjective feeling entered patients randomly assigned...

10.1002/hup.2282 article EN Human Psychopharmacology Clinical and Experimental 2012-12-20

Abstract Problem Polycystic ovary syndrome (PCOS) is associated with endoplasmic reticulum (ER) stress and pro‐inflammatory condition. The aim of the present study was to evaluate effect resveratrol treatment on ER markers in patients PCOS. Method Cumulus cells were obtained from 40 PCOS who divided into two groups: placebo (receiving 800 mg/d for days) groups. Blood samples all before after procedure interleukin (IL)‐6, IL‐1β, IL‐18, TNF‐α, NF‐κB, C‐reactive protein (CRP). Total RNA...

10.1111/aji.13186 article EN American Journal of Reproductive Immunology 2019-09-04

<b>Introduction:</b> Postpartum depression is a common mental health problem that associated with maternal suffering. The aim of this double-blind clinical trial was to compare safety and efficacy saffron fluoxetine in treatment mild moderate postpartum depression. <b>Methods:</b> This 6-week, double-blind, randomized trial. Subjects were women aged 18–45 years who had Hamilton Depression Rating Scale (HDRS 17-item) score≤18. Eligible participants receive either capsule (15 mg capsule) or...

10.1055/s-0042-115306 article EN Pharmacopsychiatry 2016-09-05

To identify novel candidate diagnostic microRNA (miRNA) markers of endometriosis by means an unbiased search with confirmation targeted polymerase chain reaction (PCR).Retrospective cohort.University teaching hospitals.Women and control women, confirmed the use laparoscopy.Diagnostic laparoscopy blood sample.Next-generation sequencing (NGS) quantitative real-time PCR (qRT-PCR).Candidate miRNAs differentially expressed in women compared were identified NGS selected for qRT-PCR. Plasma samples...

10.1016/j.fertnstert.2020.01.026 article EN cc-by-nc-nd Fertility and Sterility 2020-05-30

Clonidine-based therapies have been utilized as the main protocol for opiate detoxification several years. However, with clonidine has its limitations, including lack of efficacy mental symptoms. Accumulating evidence shows Passiflora incarnata extract in management anxiety. In our continuing study traditional medicines, which neurotropic effects, this plant had an anxiolytic effect, may be used adjuvant agent opiates by clonidine. We present results a double-blind randomized controlled...

10.1046/j.1365-2710.2001.00366.x article EN Journal of Clinical Pharmacy and Therapeutics 2001-10-01

Endometriosis is an inflammatory disease; the hallmark of inflammation over-activation matrix metalloproteinases (MMPs). The regulatory effects Resveratrol on MMPs were formerly depicted in other cell lines. This study aimed at investigating expression MMP-2 and -9 endometriosis patients. trial was carried out patients (n = 34) who randomly divided into treatment (i 17) control groups. Alongside routine protocol, groups took placebo (400 mg), respectively, for 12–14 weeks. Endometrial tissue...

10.1080/09513590.2019.1576612 article EN Gynecological Endocrinology 2019-02-19

<title>Abstract</title> Background This study compared the effectiveness of cabergoline and hydroxychloroquine in preventing ovarian hyperstimulation syndrome (OHSS) patients with polycystic ovary (PCOS) undergoing controlled stimulation. Materials Methods double-blind, parallel, randomized clinical trial was performed from April to June 2024. Forty-two PCOS who were candidates for assisted reproductive techniques into two groups. The first group received 0.5 mg cabergoline, second 400 8...

10.21203/rs.3.rs-5855263/v1 preprint EN Research Square (Research Square) 2025-04-17

This study compared the effectiveness of cabergoline and hydroxychloroquine in preventing ovarian hyperstimulation syndrome (OHSS) patients with polycystic ovary (PCOS) undergoing controlled stimulation. double-blind, parallel, randomized clinical trial was performed from April to June 2024. Forty-two PCOS who were candidates for assisted reproductive techniques into two groups. The first group received 0.5 mg cabergoline, second 400 8 days. Then, ultrasounds conducted on days 3 5 after...

10.1186/s13048-025-01702-6 article EN cc-by-nc-nd Journal of Ovarian Research 2025-05-29

Background: The aim of this study was to evaluate mental health disorders in infertile women with Polycystic Ovary Syndrome (PCOS) compared the without PCOS. Methods: These two parallel case series studies were conducted during a 12-months period from June 2020 march 2022 at Arash Hospital affiliated Tehran University Medical Sciences (TUMS). A total 69 PCOS and non-PCOS diagnosed infertility recruited into study. Symptom Checklist-90 (SCL-90) containing nine main domains: somatization,...

10.18502/jimc.v8i3.18794 article EN Journal of Iranian Medical Council 2025-05-31

Abstract Background Considering that clinical trial studies are limited in polycystic ovary syndrome (PCOS) patients, and there is no consensus on an optimum endometrial preparation protocol for frozen embryo transfer (FET), the present study was designed as a randomized to compare reproductive outcomes following stimulated cycles with letrozole plus human menopausal gonadotropin (HMG) compared routine AC-FET. Methods This controlled carried out infertile PCOS patients who underwent IVF/ICSI...

10.1186/s12958-020-00675-z article EN cc-by Reproductive Biology and Endocrinology 2020-11-20

Ovarian stimulation (OS) for poor ovarian response (POR) patients is still a major challenge in assisted reproductive techniques. Aromatase inhibitors as co-treatment antagonist protocol are suggested to these patients, but there controversial reports.To evaluate the effectiveness Letrozole (LZ) adjuvant treatment gonadotropin-releasing hormone (GnRH)-antagonist POR undergoing vitro fertilization/ intracytoplasmic sperm injection cycles.This double-blind randomized clinical trial was...

10.18502/ijrm.v17i9.5101 article EN cc-by-nc International Journal of Reproductive BioMedicine (IJRM) 2019-09-22
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