A5037378906- Lung Cancer Treatments and Mutations
- Adipokines, Inflammation, and Metabolic Diseases
- Inflammation biomarkers and pathways
- Adipose Tissue and Metabolism
- Cancer Immunotherapy and Biomarkers
- Vitamin D Research Studies
- Cardiovascular Disease and Adiposity
- Bone and Dental Protein Studies
- Diabetes and associated disorders
- Lung Cancer Diagnosis and Treatment
- Ancient Mediterranean Archaeology and History
- Cancer Research and Treatments
- Immune cells in cancer
- Metabolism and Genetic Disorders
- Bone health and osteoporosis research
- Biomarkers in Disease Mechanisms
- Lipoproteins and Cardiovascular Health
- Health Systems, Economic Evaluations, Quality of Life
- Sepsis Diagnosis and Treatment
- Celiac Disease Research and Management
- Inflammatory Biomarkers in Disease Prognosis
- Historical and Environmental Studies
- Vitamin C and Antioxidants Research
- Amino Acid Enzymes and Metabolism
- Management, Economics, and Public Policy
University of Genoa
2019-2021
Abstract Background Pro‐protein convertase subtilisin/kexin 9 (PCSK9) is a proenzyme primarily known to regulate low‐density lipoprotein receptor re‐uptake on hepatocytes. Whether PCSK9 can concurrently trigger inflammation or not remains unclear. Here, we investigated the potential association between circulating levels of and mortality in patients with severe sepsis septic shock. Methods Plasma at days 1, 2 7 were measured 958 shock previously enrolled Albumin Italian Outcome Sepsis...
Abstract Background Inflammatory biomarkers are useful in detecting patients with sepsis. The prognostic role of resistin and myeloperoxidase (MPO) has been investigated Materials Methods Plasma MPO were measured on days 1, 2 7 957 enrolled the Albumin Italian Outcome Sepsis (ALBIOS) trial. association between levels day 90‐day mortality was assessed. Results concentrations higher at 1 decreased until 7. Both positively correlated each other physiological parameters. Higher associated...
Sexual dimorphism accounts for significant differences in adipose tissue mass and distribution. However, how the crosstalk between visceral ectopic fat depots occurs which are determinants of expansion dysfunction remains unknown. Here, we focused on impact gender epicardial role adipocytokines high-sensitivity C-reactive protein (hs-CRP). A total 141 outward patients (both men women) with one or more defining criteria metabolic syndrome (MetS) were consecutively enrolled. For all patients,...
Abstract Background High circulating levels of cellular adhesion molecules (CAMs) in non‐small cell lung cancer (NSCLC) have been supposed to act as a negative prognostic factor. Here, we explored the predictive role pre‐treatment CAMs previously treated patients receiving nivolumab for NSCLC. Materials and methods Seventy one with advanced NSCLC, at dose 3 mg/kg every 14 days, were enrolled. Maximum follow‐up time was years. Serum Vascular Cell Adhesion Molecule‐1 (VCAM‐1) Intracellular...
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