Laura J. Huston

ORCID: 0000-0002-9901-7165
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About
Contact & Profiles
Research Areas
  • Knee injuries and reconstruction techniques
  • Total Knee Arthroplasty Outcomes
  • Sports injuries and prevention
  • Shoulder Injury and Treatment
  • Osteoarthritis Treatment and Mechanisms
  • Lower Extremity Biomechanics and Pathologies
  • Shoulder and Clavicle Injuries
  • Orthopedic Surgery and Rehabilitation
  • Muscle activation and electromyography studies
  • Sports Performance and Training
  • Tendon Structure and Treatment
  • Radiomics and Machine Learning in Medical Imaging
  • Musculoskeletal synovial abnormalities and treatments
  • Orthopaedic implants and arthroplasty
  • Orthopedic Infections and Treatments
  • Adhesion, Friction, and Surface Interactions
  • Nerve Injury and Rehabilitation
  • Peptidase Inhibition and Analysis
  • Advanced X-ray and CT Imaging
  • Pulmonary Hypertension Research and Treatments
  • Renin-Angiotensin System Studies
  • Pregnancy-related medical research
  • Textile materials and evaluations
  • Electrical Contact Performance and Analysis
  • Veterinary Equine Medical Research

Vanderbilt University
2015-2025

Vanderbilt University Medical Center
2016-2025

Cleveland Clinic
2016-2025

Nashville Oncology Associates
2024

University of California, Los Angeles
2024

Washington University Medical Center
2024

The Ohio State University
2016-2023

Brooke Army Medical Center
2023

Washington University in St. Louis
2013-2023

LinkedIn (United States)
2023

The incidence of noncontact anterior cruciate ligament injuries in young to middle-aged athletes remains high. Despite early diagnosis and appropriate operative nonoperative treatments, posttraumatic degenerative arthritis may develop. In a meeting Atlanta, Georgia (January 2005), sponsored by the American Orthopaedic Society for Sports Medicine, group physicians, physical therapists, athletic trainers, biomechanists, epidemiologists, other scientists interested this area research met review...

10.1177/0363546506286866 article EN The American Journal of Sports Medicine 2006-08-11

The purpose of this research was to identify possible predisposing neuromuscular factors for knee injuries, particularly anterior cruciate ligament tears in female athletes by investigating laxity, lower extremity muscle strength, endurance, reaction time, and recruitment order response tibial translation. We recruited four subject groups: elite (N = 40) male 60) sex-matched nonathletic controls 40). All participants underwent a subjective evaluation function, arthrometer measurement...

10.1177/036354659602400405 article EN The American Journal of Sports Medicine 1996-07-01

Background Revision anterior cruciate ligament (ACL) reconstruction has worse outcomes than primary reconstructions. Predictors for these are not known. The Multicenter ACL Study (MARS) Group was developed to perform a multisurgeon, multicenter prospective longitudinal study obtain sufficient subjects allow multivariable analysis determine predictors of clinical outcome. Purpose To describe the formation MARS and provide descriptive patient demographics features initial 460 enrolled patients...

10.1177/0363546510378645 article EN The American Journal of Sports Medicine 2010-10-01

Anterior cruciate ligament injury rates are four to eight times higher in women than men. Because of estrogen's direct effect on collagen metabolism and behavior because neuromuscular performance varies during the menstrual cycle, it is logical question cycle's knee rates. Of 40 consecutive female athletes with acute anterior injuries (less 3 months), 28 (average age, 23 +/- 11 years) met study criteria regular periods noncontact injury. Details concerning mechanism injury, contraceptive...

10.1177/03635465980260050301 article EN The American Journal of Sports Medicine 1998-09-01

Anterior cruciate ligament injury rates are reported to be two eight times higher in women than men within the same sport. Because menstrual cycle with its monthly hormonal fluctuations is one of most basic differences between and women, we investigated association distribution confirmed anterior tears phase. Sixty-nine female athletes who sustained an acute were studied 24 hours at four centers. The mechanism injury, details, use oral contraceptives, history previous recorded. Urine samples...

10.1177/03635465020300020601 article EN The American Journal of Sports Medicine 2002-03-01
Rick W. Wright Laura J. Huston Amanda K. Haas Kurt P. Spindler Sam Nwosu and 88 more Christina R. Allen Allen F. Anderson Daniel E. Cooper Thomas M. DeBerardino Warren R. Dunn Brett A. Lantz Michael J. Stuart Elizabeth A. Garofoli John P. Albright Annunziato Amendola Jack T. Andrish Christopher C. Annunziata Robert A. Arciero Bernard R. Bach Champ L. Baker Arthur R. Bartolozzi Keith M. Baumgarten Jeffery R. Bechler Jeffrey H. Berg Geoffrey A. Bernas Stephen F. Brockmeier Robert H. Brophy Charles A. Bush‐Joseph J. Brad Butler John Campbell James L. Carey James E. Carpenter Brian J. Cole Jonathan M. Cooper Charles L. Cox R. Alexander Creighton Diane L. Dahm Tal S. David David C. Flanigan Robert W. Frederick Theodore J. Ganley Charles J. Gatt Steven R. Gecha J. Robert Giffin Sharon L. Hame Jo A. Hannafin Christopher D. Harner Norman Lindsay Harris Keith S. Hechtman Elliott B. Hershman Rudolf G. Hoellrich Timothy M. Hosea David C. Johnson Timothy S. Johnson Morgan H. Jones Christopher C. Kaeding Ganesh V. Kamath Thomas E. Klootwyk Bruce A. Levy C. Benjamin G. Peter Maiers Robert G. Marx Matthew J. Matava Gregory M. Mathien David R. McAllister Eric C. McCarty Robert G. McCormack Bruce S. Miller Carl W. Nissen Daniel F. O’Neill Brett D. Owens Richard D. Parker Mark L. Purnell Arun J. Ramappa Michael A. Rauh Arthur C. Rettig Jon K. Sekiya Kevin G. Shea Orrin H. Sherman James R. Slauterbeck Matthew V. Smith Jeffrey T. Spang Steven J. Svoboda Timothy N. Taft Joachim J. Tenuta Edwin M. Tingstad Armando F. Vidal Darius G. Viskontas Richard A. White James S. Williams Michelle L. Wolcott Brian R. Wolf James J. York

Background: Most surgeons believe that graft choice for anterior cruciate ligament (ACL) reconstruction is an important factor related to outcome; however, revision may be limited due previously used grafts. Hypotheses: Autograft use would result in increased sports function, activity level, and decreased osteoarthritis symptoms (as measured by validated patient-reported outcome instruments). failure reoperation rate 2 years after ACL reconstruction. Study Design: Cohort study; Level of...

10.1177/0363546514549005 article EN The American Journal of Sports Medicine 2014-09-30

Identifying risk factors for inferior outcomes after anterior cruciate ligament reconstruction (ACLR) is important prognosis and future treatment.Articular cartilage lesions meniscus tears/treatment would predict International Knee Documentation Committee (IKDC) score, injury Osteoarthritis Outcome Score (KOOS) (all 5 subscales), Marx activity level at 6 years ACLR.Cohort study (prognosis); Level of evidence, 1.Between 2002 2004, a total 1512 ACLR patients were prospectively enrolled...

10.1177/0363546514525910 article EN The American Journal of Sports Medicine 2014-03-19

Background: The long-term prognosis and risk factors for quality of life disability after anterior cruciate ligament (ACL) reconstruction remain unknown. Hypothesis/Purpose: Our objective was to identify patient-reported outcomes patient-specific from a large prospective cohort at minimum 10-year follow-up ACL reconstruction. We hypothesized that meniscus articular cartilage injuries, revision reconstruction, subsequent knee surgery, certain demographic characteristics would be significant...

10.1177/0363546517749850 article EN The American Journal of Sports Medicine 2018-03-01

Anterior cruciate ligament (ACL) reconstruction rehabilitation has evolved over the past 20 years. This evolution been driven by a variety of level 1 and 2 studies.The MOON Group is collection orthopaedic surgeons who have developed prospective longitudinal cohort ACL patients. To standardize management these patients, we developed, in conjunction with our physical therapy committee, an evidence-based guideline.Clinical review.Level 2.This review was based on systematic reviews studies....

10.1177/1941738113517855 article EN Sports Health A Multidisciplinary Approach 2014-01-17

Background: The predictors of anterior cruciate ligament reconstruction (ACLR) outcome at 6 years as measured by validated patient-based instruments are unknown. Hypothesis: Certain variables evaluated the time ACLR will predict return to sports function (as International Knee Documentation Committee [IKDC] questionnaire and injury Osteoarthritis Outcome Score [KOOS] Sports Recreation subscale), knee-related quality life (KOOS Related Quality Life activity level (Marx Activity Scale)....

10.1177/0363546510383481 article EN The American Journal of Sports Medicine 2010-11-17

We investigated the effect of quadriceps and hamstring muscle fatigue on anterior tibial translation reaction time in 10 healthy subjects. The six men four women had an average age 21.3 years no known pathologic knee conditions. Each patient underwent a examination, arthrometer measure ments translation, subjective functional assess ment, stress test be fore after muscle- fatiguing exercise. recruitment order lower extremity muscles response to trans lation did not change with fatigue....

10.1177/036354659602400509 article EN The American Journal of Sports Medicine 1996-09-01

An instrumented cadaveric knee construct was used to quantify the association between impact force, quadriceps flexion angle, and anterior cruciate ligament relative strain in simulated unipedal jump landings.Anterior will correlate with angle.Descriptive laboratory study.Eleven knees (age, 70.8 [19.3] years; 5 male; 6 female) were mounted a custom fixture tibia femur secured triaxial load cell. Quadriceps, hamstring, gastrocnemius muscle forces using pretensioned steel cables (stiffness, 7...

10.1177/0363546505280906 article EN The American Journal of Sports Medicine 2005-11-01

Background: Female athletes who participate in sports involving jumping and cutting maneuvers are up to eight times more likely sustain a rupture of the anterior cruciate ligament than men participating same sports. We tested hypothesis that healthy young women able volitionally increase apparent torsional stiffness knee, by maximally activating knee muscles, significantly less size-matched type sport. Methods: Twenty-four NCAA (National Collegiate Athletic Association) Division-I (twelve...

10.2106/00004623-200305000-00002 article EN Journal of Bone and Joint Surgery 2003-05-01
James Borchers Christopher C. Kaeding Angela Pedroza Laura J. Huston Kurt P. Spindler and 92 more Rick W. Wright John P. Albright Christina R. Allen Annunziato Amendola Allen F. Anderson Jack T. Andrish Christopher C. Annunziata Robert A. Arciero Bernard R. Bach Champ L. Baker Arthur R. Bartolozzi Keith M. Baumgarten Jeffery R. Bechler Jeffrey H. Berg Geoff Bernas James Borchers Stephen F. Brockmeier Robert H. Brophy Charles A. Bush‐Joseph J. Brad Butler John D. Campbell James L. Carey James E. Carpenter Brian J. Cole Daniel E. Cooper Jonathan M. Cooper Charles L. Cox R. Alexander Creighton Diane L. Dahm Tal S. David Thomas M. DeBerardino Warren R. Dunn David C. Flanigan Robert W. Frederick Charles J. Gatt Steven R. Gecha J. Robert Giffin Donald B. Goodfellow Amanda K. Haas Sharon L. Hame Jo A. Hannafin Christopher D. Harner Norman Lindsay Harris Keith S. Hechtman Elliott B. Hershman Rudolf G. Hoellrich Timothy M. Hosea Laura J. Huston David C. Johnson Timothy S. Johnson Morgan H. Jones Christopher C. Kaeding Thomas E. Klootwyk Brett A. Lantz Bruce A. Levy C. Benjamin G. Peter Maiers Barton J. Mann Robert G. Marx Matthew J. Matava Gregory M. Mathien David R. McAllister Eric C. McCarty Robert G. McCormack Bruce S. Miller Ali R. Motamedi Carl W. Nissen Daniel F. O’Neill Richard D. Parker Angela Pedroza Mark L. Purnell Arun J. Ramappa Michael A. Rauh Arthur C. Rettig Jon K. Sekiya Kevin G. Shea Orrin H. Sherman James R. Slauterbeck Kurt P. Spindler Michael J. Stuart Steven J. Svoboda Timothy N. Taft Joachim J. Tenuta Edwin M. Tingstad Armando F. Vidal Darius G. Viskontas Richard A. White James S. Williams Michelle L. Wolcott Brian R. Wolf Rick W. Wright James J. York

Background: At the time of anterior cruciate ligament (ACL) reconstruction, there are usually concurrent meniscal and articular cartilage injuries. It is unclear if a significant difference between intra-articular injuries at primary ACL reconstruction compared with revision reconstruction. Purpose: To compare found surgery to determine associations specific findings. Study Design: Cohort study (prevalence); Level evidence, 2. Methods: Primary surgeries were identified from Multicenter...

10.1177/0363546511406871 article EN The American Journal of Sports Medicine 2011-06-06

The hamstring muscles are well positioned to limit both anterior tibial translation and cruciate ligament strain during the knee flexion phase of a jump landing. We hypothesized that systematically increasing or decreasing tension simulated landing would significantly affect peak relative in ligament.Ten cadaveric knees from four male six female donors (mean age [and standard deviation] at time death, 60.3 +/- 23.6 years) were mounted custom fixture initially position specimen 25 degrees...

10.2106/jbjs.f.01352 article EN Journal of Bone and Joint Surgery 2008-04-01

Background: Meniscal repair is commonly performed concurrently with anterior cruciate ligament reconstruction (ACLR) in the acutely injured knee. No large-scale, prospective multicenter studies have evaluated long-term success and patient-oriented outcomes after combined ACLR meniscal repair. Purpose: To define operative outcome scores 6 years ACLR. Study Design: Cohort study; Level of evidence, 3. Methods: All ipsilateral primary cases from a study group between 2002 2004 were selected....

10.1177/0363546514536022 article EN The American Journal of Sports Medicine 2014-07-14
James L. Chen Christina R. Allen Thomas E. Stephens Amanda K. Haas Laura J. Huston and 90 more Rick W. Wright Brian T. Feeley John P. Albright Annunziato Amendola Allen F. Anderson Jack T. Andrish Christopher C. Annunziata Robert A. Arciero Bernard R. Bach Champ L. Baker Arthur R. Bartolozzi Keith M. Baumgarten Jeffery R. Bechler Jeffrey H. Berg Geoff Bernas Stephen F. Brockmeier Robert H. Brophy Charles A. Bush‐Joseph J. Brad Butler John D. Campbell James L. Carey James E. Carpenter Brian J. Cole Daniel E. Cooper Jonathan M. Cooper Charles L. Cox R. Alexander Creighton Diane L. Dahm Tal S. David Thomas M. DeBerardino Warren R. Dunn David C. Flanigan Robert W. Frederick Theodore J. Ganley Charles J. Gatt Steven R. Gecha J. Robert Giffin Sharon L. Hame Jo A. Hannafin Christopher D. Harner Norman Lindsay Harris Keith S. Hechtman Elliott B. Hershman Rudolf G. Hoellrich Timothy M. Hosea David C. Johnson Timothy S. Johnson Morgan H. Jones Christopher C. Kaeding Ganesh V. Kamath Thomas E. Klootwyk Brett A. Lantz Bruce A. Levy C. Benjamin G. Peter Maiers Barton J. Mann Robert G. Marx Matthew J. Matava Gregory M. Mathien David R. McAllister Eric C. McCarty Robert G. McCormack Bruce S. Miller Carl W. Nissen Daniel F. O’Neill MAJ Brett D. Owens Richard D. Parker Mark L. Purnell Arun J. Ramappa Michael A. Rauh Arthur C. Rettig Jon K. Sekiya Kevin G. Shea Orrin H. Sherman James R. Slauterbeck Matthew V. Smith Jeffrey T. Spang Kurt P. Spindler Michael J. Stuart LTC Steven J. Svoboda Timothy N. Taft COL Joachim J. Tenuta Edwin M. Tingstad Armando F. Vidal Darius G. Viskontas Richard A. White James S. Williams Michelle L. Wolcott Brian R. Wolf James J. York

The factors that lead to patients failing multiple anterior cruciate ligament (ACL) reconstructions are not well understood.Multiple-revision ACL reconstruction will have different characteristics than first-time revision in terms of previous and current graft selection, mode failure, chondral/meniscal injuries, surgical charactieristics.Case-control study; Level evidence, 3.A prospective multicenter database was utilized for the time period from March 2006 June 2011. Patients were divided...

10.1177/0363546513487980 article EN The American Journal of Sports Medicine 2013-05-22

Background: Rehabilitation before anterior cruciate ligament (ACL) reconstruction (ACLR) is effective at improving postoperative outcomes least in the short term. Less known about effects of preoperative rehabilitation on functional and return-to-sport (RTS) rates 2 years after reconstruction. Purpose/Hypothesis: The purpose this study was to compare ACLR a cohort that underwent additional rehabilitation, including progressive strengthening neuromuscular training impairments were resolved,...

10.1177/0363546516652594 article EN The American Journal of Sports Medicine 2016-07-15

Background: Physicians’ and patients’ decision-making process between bone–patellar tendon–bone (BTB) hamstring tendon autografts for anterior cruciate ligament (ACL) reconstruction (ACLR) may be influenced by a variety of factors in the young, active athlete. Purpose: To determine incidence both ACL graft revisions contralateral tears resulting subsequent ACLR cohort high school– college-aged athletes who initially underwent primary with either BTB or autograft. Study Design: Cohort study;...

10.1177/0363546519892991 article EN The American Journal of Sports Medicine 2020-01-09
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