- Remote-Sensing Image Classification
- Remote Sensing and Land Use
- Plant Stress Responses and Tolerance
- Remote Sensing in Agriculture
- Geographic Information Systems Studies
- Heavy metals in environment
- Renal cell carcinoma treatment
- Human Mobility and Location-Based Analysis
- Plant responses to water stress
- Plant nutrient uptake and metabolism
- MRI in cancer diagnosis
- HIV/AIDS drug development and treatment
- Water Quality and Pollution Assessment
- Heavy Metal Exposure and Toxicity
- Renal and related cancers
- HIV Research and Treatment
- Meningioma and schwannoma management
- Data Management and Algorithms
- 3D Modeling in Geospatial Applications
- Calibration and Measurement Techniques
- Radiomics and Machine Learning in Medical Imaging
- Advanced Measurement and Metrology Techniques
- Photoacoustic and Ultrasonic Imaging
- Plant Molecular Biology Research
- Advancements in Battery Materials
Chinese PLA General Hospital
2023-2025
Jiangxi University of Finance and Economics
2023-2025
Guangzhou Institute of Geography
2020-2024
Northwest A&F University
2024
Xuzhou Medical College
2020-2024
Tianjin University
2021-2024
Emissions Reduction Alberta
2023
Chinese Academy of Sciences
2011-2022
Tianjin University of Technology
2021-2022
Qingdao Agricultural University
2022
This study collected past sampling data on total concentrations of 12 heavy metals (Cd, Pb, Cr, Hg, Zn, Cu, Ni, Al, Fe, Mn, As, and Co) in surface water bodies, i.e., 168 rivers 71 lakes, from 1972 to 2017. The intent was investigate the levels sources metal pollution across five decades continents. Mean global river lake water, number with greater than published threshold limits as per standards both World Health Organization (WHO) United States Environmental Protection Agency (USEPA) were...
The SARC-F scale is a newly developed tool to diagnose sarcopenia and obviate the need for measurement of muscle mass. ≥ 4 defined as sarcopenia. questions cover physical functions targeting or initial presentation aim study explore application in Chinese people. Two hundred thirty people over 65 years old were assessed by scale, PSMS, Lawton IADL shortened version falls efficacy scale-international (the short FES-I). Hospitalization was investigated. Physical performance strength measured....
Abstract Background and Aims Most primary auxin response genes are classified into three families: AUX/IAA, GH3 SAUR genes. Few studies have been conducted on Arabidopsis thaliana genes, possibly due to genetic redundancy among different subfamily members. Data mining arabidopsis transcriptional profiles indicates that the SAUR41 members of SMALL AUXIN UP RNA are, strikingly, induced by an inhibitory phytohormone, abscisic acid (ABA). We aimed reveal physiological roles containing SAUR40,...
Seed vigor in crops is important terms of improving grain quality and germplasm conservation; however, little known about its regulatory mechanisms through the encoded proteome gene network. Comparative analyses transcriptome (RNA sequencing [RNA-seq]) broadly targeted metabolic profiling two subspecific rice cultivars with distinct seed during accelerated aging revealed various biological pathways processes as key influences explaining trait differences. RNA-seq coexpression network...
Peptides derived from the C-terminal heptad repeat (CHR) region of human immunodeficiency virus type 1 (HIV-1) fusogenic protein gp41 are potent viral entry inhibitors, and currently, enfuvirtide (T-20) is only one approved for clinical use; however, emerging drug resistance largely limits its efficacy. In this study, we generated a novel lipopeptide inhibitor, named LP-19, by integrating multiple design strategies, including an N-terminal M-T hook structure, HIV-2 sequence, intrahelical...
Incorporating multiple molecular interactions within a system to realize the metabolic reprogramming of cancer cells is prospected be great potential in therapy. Herein, we report supramolecular self-assembled DNA nanosystem, which reprogrammed cellular antioxidant via synergistic chemical and gene regulations. In amphipathic telluroether was coordinated with MnII self-assemble into micelle, on siNrf2 integrated network assembled. The electron-donating capability revealed greatly promote...
Abstract Cucurbitacin-I (Cu-I, also known as Elatericin B or JSI-124) is developed to inhibit constitutive and abnormal activation of STAT3 in many cancers, demonstrating a potent anticancer activity by targeting disruption function. Here, we for the first time systematically studied underlying molecular mechanisms Cu-I-induced gastric cancer cell death both vitro vivo . In our study, show that Cu-I markedly inhibits growth inducing G2/M phase cycle arrest apoptosis at low nanomolar...
The peptide drug T20 (enfuvirtide), derived from the C-terminal heptad repeat region of HIV-1 gp41, is only membrane fusion inhibitor available for treatment viral infection; however, its mechanism action remains elusive and structural basis lacking.We focused on determining crystal structure in complex with N39, a target mimic N-terminal gp41. On information, mechanisms resistance were further characterized.A panel peptides was synthesized. T20/N39 assembled crystallization studies....
Frailty and cognitive impairment are significant problems faced by older adults, which have a impact on their activities of daily living, social activities, quality life.Cross-sectional study.A total 252 adults in two communities Yangzhou were randomly selected. The function the elderly was assessed using Memory Executive Screening (MES). frailty phenotype used to evaluate frail situation adults. activity living (ADL), functional questionnaire (FAQ), European 5-dimensions (EQ-5D) health...
Chenopodium album L. is a troublesome annual species in various cropping systems, and sound knowledge of the ecological response C . germination to environmental factors would suggest suitable management strategies for inhibiting its spread. Preliminary laboratory-based research was conducted investigate emergence requirements under conditions (e.g., photoperiods, constant temperature, salinity, moisture, soil pH, burial depth, oat crop residue). Results showed seeds were found be...
The number of clusters (i.e., the classes) for unsupervised classification has been recognized as an important part remote sensing image clustering analysis. classes is usually determined by cluster validity indices (CVIs). Although many CVIs have proposed, few studies compared and evaluated their effectiveness on datasets. In this paper, performance 16 representative commonly-used was comprehensively tested applying fuzzy c-means (FCM) algorithm to nine types datasets, including...
The agricultural landscape can be interpreted at different semantic levels, such as fine low-level crop (LLC) classes (e.g., Wheat, Almond, and Alfalfa) broad high-level (HLC) Winter crops, Tree Forage). LLC HLC are hierarchically correlated with each other, but intrinsically hierarchical relationships have been overlooked in previous classification studies remote sensing. In this research, a novel Iterative Deep Learning (IDL) framework was proposed for the of complex landscapes using...
The highly dynamic nature of agro-ecosystems in space and time usually leads to high intra-class variance low inter-class separability the fine spatial resolution (FSR) remotely sensed imagery. This makes traditional classifiers essentially relying on spectral information for crop mapping from FSR imagery an extremely challenging task. To mine effectively rich imagery, this paper proposed a Scale Sequence Object-based Convolutional Neural Network (SS-OCNN) that classifies images at object...
From 2020 to 2022, hydrological extremes such as severe floods and droughts occurred successively in Jiujiang city, Poyang Lake Basin, posing a threat regional water quality safety. The chlorophyll-a (Chl-a) concentration is key indicator of river eutrophication. Until now, there has been lack empirical research exploring the Chl-a trend inland context extremes. In this study, Sentinel-2 satellite remote sensing data sourced from Google Earth Engine (GEE) cloud platform, along with hourly...
iPSC-derived natural killer cells (iNKs) have emerged as a promising cellular therapy, especially for the refractory or relapsed acute myeloid leukemia (R/R AML) patients, but limited research focused on chemotaxis of iNKs. Here we demonstrate that C-X-C chemokine receptor type 4 (CXCR4) is significantly reduced in iNKs, resulting impaired bone marrow (BM) infiltration, which cannot be rescued by constitutively expressed CXCR4 iPSC due to CXCR4-induced differentiation failure. To address...
During myocardial ischemia, the cranial cervical spinal cord (C1-C2) modulates central processing of cardiac nociceptive signal. This study was done to determine 1) whether C2 SCS-induced release an analgesic neuropeptide in dorsal horn thoracic (T4) cord; 2) if one sources this peptide propriospinal neurons, and 3) chemical inactivation neurons altered local T4 substance P (SP) during concurrent SCS ischemia. Ischemia induced by intermittent occlusion left anterior descending coronary...
The upper cervical spinal region functions as an intraspinal controller of thoracic reflexes and contributes to neuronal regulation the ischemic myocardium. Our objective was determine whether stimulation C2 cord (SCS) rats modified input signal at when cardiac ischemia-sensitive (sympathetic) afferents were activated by transient occlusion left anterior descending coronary artery (CoAO). Changes in c-Fos expression used index activation within brain stem. pattern substance P (SP) release, a...
The ant colony algorithm (ACA) has been widely used for reducing the dimensionality of hyperspectral remote sensing imagery. However, ACA suffers from problems slow convergence and local optima (caused by loss population diversity). This paper proposes an improved (IMACA) based band selection (IMACA-BS), to overcome two shortcomings standard ACA. For former problem, a pre-filter is applied improve heuristic desirability system; Pearson's similarity measurement degree redundancy among...