A5033738408- Cleft Lip and Palate Research
- Craniofacial Disorders and Treatments
- Dental Radiography and Imaging
- RNA modifications and cancer
- Oral and Maxillofacial Pathology
- Folate and B Vitamins Research
- Facial Trauma and Fracture Management
- Temporomandibular Joint Disorders
- Tracheal and airway disorders
- Orthodontics and Dentofacial Orthopedics
- Nasal Surgery and Airway Studies
- Tumors and Oncological Cases
- Congenital Anomalies and Fetal Surgery
- Soft tissue tumor case studies
- Obstructive Sleep Apnea Research
- Epigenetics and DNA Methylation
- Bone Tumor Diagnosis and Treatments
- Maternal and Perinatal Health Interventions
- Medical and Biological Sciences
- Clay minerals and soil interactions
- Breastfeeding Practices and Influences
- Dental Anxiety and Anesthesia Techniques
- Dental Trauma and Treatments
- Peripheral Nerve Disorders
- Laser Applications in Dentistry and Medicine
University of Chile
2013-2025
Hospital San Borja Arriarán
2012-2025
To assess the association between polymorphic variants from SHMT1 and MTHFS genes, involved in cytoplasmic futile folate cycle, risk of nonsyndromic cleft lip with or without palate (NSCL/P) Chilean population.In a sample 139 NSCL/P cases 278 controls, we obtained genotypes for nine them phenotype was evaluated using odds ratios (OR) additive (allele), dominant, recessive models.After correction multiple comparisons, only variant rs1979277 (G > A; p.Leu474Phe) showed significant protective...
Aim: To evaluate the risk of nonsyndromic orofacial clefts (NSOFCs) associated with LINE-1 methylation, as a marker global DNA and effect MTHFR functional variants on this variable. Patients & methods: methylation was evaluated by bisulfite modification coupled to pyrosequencing in 95 NSOFC cases controls. In these subjects, genotypes for c.C677T (rs1801133) c.A1298C (rs1801131) were obtained. Results: Middle levels (second tertile) increase NSOFCs. addition, depends controls but not cases....
The objective of this work is to describe a segmental maxillary distraction osteogenesis (SDO) with Lefort I an inexpensive device.Four patients who presented severe class III and hypoplasia due cleft lip palate sequel were treated. A SDO was performed using dental-anchored Hyrax device, achieving enlargement the upper jaw without altering speech, adequate stable occlusion. Dental implants in new formed bone installed.The authors can conclude that good treatment alternative for hypoplasia....
A series of skeletal and dentoalveolar/occlusal criteria were proposed for choosing the treatment modality management midface hypoplasia in cleft lip/palate patients, focusing on functional improvement, aesthetics, minimizing risk recurrence secondary alterations. For which, 42 patients with nonsyndromic lip/palate, all previous primary surgeries without osteotomies, analyzed. Orthognathic surgery (OS) (n = 24) maxillary distraction osteogenesis 18) anterior segmental osteotomies (segmental...
Abstract The aim of this study was to evaluate, in a case‐control design, the association between maternal genotypes for variants 23 genes involved folate/one‐carbon metabolism and nonsyndromic cleft lip with or without palate (NSCL/P) Chilean population. After applying several filters an Illumina array, we extracted 175 single nucleotide polymorphisms (SNPs) from 150 mothers NSCL/P cases control women. Association evaluated using computed odds ratio (OR) 95% confidence interval (95% CI)...
Describir el perfil epidemiológico de los pacientes con FLMP no sindrómica acuerdo a factores que involucran la madre. Estudio tipo observacional, retrospectivo y analÃtico partir datos casos sindrómicos. Se clasifico las variables Fueron evaluadas 236 fichas completas pacientes. Un 56,60 % pertenecen al sexo masculino 43,40 femenino. El mayor porcentaje nació año 2011 (15,57 %), FLP es más prevalente (44,92 26,67 madres tenÃa entre 21-25 años momento del parto, un 80,50 87,50...
La fisura labio máxilo palatina (FLMP) es un problema de salud pública en Chile. Consiste la falta fusión del y/o los procesos palatinos, generando desequilibrio músculo esqueletal que impide el desarrollo facial normal. Afectando algunas funciones vitales como respiración, succión y deglución pudiendo ocasionar problemas nutricionales. Evaluar crecimiento estaturo ponderal acceso a lactancia materna niños con comparados sin durante primer año vida. Estudio tipo observacional,...
Infant facial fracture incidence is low. Most reported cases affect the jaw and are single fractures. We present a twenty-two-month old patient, who had high-energy car accident. Among other injures, she suffered multiple mandibular fracture: bicondylar, left body right parasymphyseal. Stable internal fixation of parasymphyseal was performed on third day. Condylar fractures functional treatment with switching elastic traction to prevent ankylosis. Computed tomography (CT) showed condyles...
La osteotomía sagital de rama mandibular bilateral es uno los procedimientos quirúrgicos más comunes durante la cirugía ortognática. Con relación a ello se han descrito múltiples reportes que indican cambios nivel neurosensitivo en el nervio alveolar inferior. Los rangos posquirúrgicos parestesia sido descritos entre un 12,5 y 100%. El objetivo este trabajo fue determinar porcentaje recuperación sensitiva del territorio inervado por inferior después una primer año postoperatorio. Se incluyó...
Resumen Objetivo Comparar el area disponible en tres planos del meato inferior pacientes operados de fisura labio-maxilo-palatina unilateral, con respecto a la los no fisurados. Material y metodo Correspondio un estudio corte transversal. La muestra consistio grupo 29 unilateral entre 5 17 anos, controlados Hospital San Borja Arriaran Facultad Odontologia Universidad Chile, control fisurados, pareados por genero edad estudio. El fue definida como espacio anatomicamente cada para flujo aereo....
Objetivo: Determinar los tipos de dismorfosis dentofaciales (DDF) operados en el Hospital ClÃnico San Borja Arriarán, Santiago, Chile (HCSBA) entre años 1993 - 2015 y su distribución por sexo edad al momento la intervención quirúrgica.
Aim: To assess the association between PEMT variants and nonsyndromic cleft lip with or without palate in Chile effects of these on global DNA methylation. Subjects & methods: The authors obtained genotypes for nine from 247 cases 453 controls genotype–phenotype associations. effect significant polymorphisms methylation (percentage long interspersed element-1 methylation) was evaluated a subsample 95 controls. Results: After multiple comparison corrections, rs7649 rs4646409 were associated...
Comparar el área disponible en tres planos del meato inferior pacientes operados de fisura labio-máxilo-palatina unilateral, con respecto a la los no fisurados. Correspondió un estudio corte transversal. La muestra consistió grupo 29 unilateral entre 5 y 17 años, controlados Hospital San Borja Arriarán Facultad Odontología Universidad Chile, control fisurados, pareados por género edad estudio. El fue definida como espacio anatómicamente cada para flujo aéreo. Esta medida fosa nasal distintas...