Jorge E. Tolosa
A5040569345- Pregnancy and preeclampsia studies
- Maternal and Perinatal Health Interventions
- Preterm Birth and Chorioamnionitis
- Gestational Diabetes Research and Management
- Maternal and fetal healthcare
- Birth, Development, and Health
- Pregnancy-related medical research
- Pelvic floor disorders treatments
- Neonatal Respiratory Health Research
- Global Maternal and Child Health
- Assisted Reproductive Technology and Twin Pregnancy
- Reproductive tract infections research
- Smoking Behavior and Cessation
- Bariatric Surgery and Outcomes
- Reproductive Health and Contraception
- Pregnancy and Medication Impact
- COVID-19 Impact on Reproduction
- Infant Development and Preterm Care
- Maternal Mental Health During Pregnancy and Postpartum
- Cardiovascular Issues in Pregnancy
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Syphilis Diagnosis and Treatment
- Neonatal and Maternal Infections
- Congenital Diaphragmatic Hernia Studies
- Breastfeeding Practices and Influences
St. Luke's University Health Network
2018-2025
Oregon Health & Science University
2015-2024
Federación de Aseguradores Colombianos
2015-2024
Universidad Pontificia Bolivariana
2020-2022
Thomas Jefferson University
1999-2021
George Washington University
2010-2021
University of North Carolina at Chapel Hill
2013-2021
Beth Israel Deaconess Medical Center
2021
Harvard University
2021
Northwestern University
2015-2020
Women who were in the 24th to 31st week of gestation and met criteria for mild gestational diabetes mellitus (i.e., an abnormal result on oral glucose-tolerance test but a fasting glucose level below 95 mg per deciliter [5.3 mmol liter]) randomly assigned usual prenatal care (control group) or dietary intervention, self-monitoring blood glucose, insulin therapy, if necessary (treatment group). The primary outcome was composite stillbirth perinatal death neonatal complications, including...
Infants who are born at 34 to 36 weeks of gestation (late preterm) greater risk for adverse respiratory and other outcomes than those 37 or later. It is not known whether betamethasone administered women late preterm delivery decreases the risks neonatal morbidities. We conducted a multicenter, randomized trial involving with singleton pregnancy 0 days 5 were high during period (up 6 days). The participants assigned receive two injections matching placebo 24 hours apart. primary outcome was...
Subclinical thyroid disease during pregnancy may be associated with adverse outcomes, including a lower-than-normal IQ in offspring. It is unknown whether levothyroxine treatment of women who are identified as having subclinical hypothyroidism or hypothyroxinemia improves cognitive function their children. We screened singleton before 20 weeks gestation for hypothyroidism, defined thyrotropin level 4.00 mU more per liter and normal free thyroxine (T4) (0.86 to 1.90 ng deciliter [11 24 pmol...
In Brief OBJECTIVE: To evaluate pregnancy outcomes according to 2009 Institute of Medicine (IOM) gestational weight gain guidelines. METHODS: This study is a secondary analysis preeclampsia prevention trial among nulliparas carrying singletons. Odds ratios and 95% confidence intervals (adjusted for maternal age, race, smoking, treatment group) were calculated based on total below or above the IOM guidelines stratified by prepregnancy body mass index (BMI). The referent group was within...
In Brief OBJECTIVE: To estimate the frequency of severe maternal morbidity, assess its underlying etiologies, and develop a scoring system to predict occurrence. Supplemental Digital Content is Available in Text. METHODS: This was secondary analysis Eunice Kennedy Shriver National Institute Child Health Human Development Maternal-Fetal Medicine Units Network cohort 115,502 women their neonates born 25 hospitals across United States over 3-year period. Women were classified as having...
To identify clinical characteristics and biochemical markers in first-trimester samples that would possibly predict the subsequent development of preeclampsia.
In Brief OBJECTIVE: To examine the relationship between varying degrees of maternal hyperglycemia and pregnancy outcomes. METHODS: This was a secondary analysis treatment trial for mild gestational diabetes including four cohorts: 1) 473 women with untreated diabetes; 2) 256 positive 50-g screen one abnormal oral glucose tolerance test (OGTT) value; 3) 675 no OGTT values; 4) 437 normal screen. Groups were compared by trend composite perinatal outcome (neonatal hypoglycemia,...
To estimate whether there is an association between excessive early gestational weight gain and the development of diabetes mellitus (GDM) fetal growth.
To compare morbidity among small-for-gestational-age (SGA; birth weight less than the 10th percentile for gestational age), appropriate-for-gestational-age (AGA; to 90th percentile; reference group), and large-for-gestational-age (LGA; greater percentile) neonates in apparently uncomplicated pregnancies at term (37 weeks of gestation or greater).
OBJECTIVE: To evaluate the association between gestational weight gain and maternal neonatal outcomes in a large, geographically diverse cohort. METHODS: Trained chart abstractors at 25 hospitals obtained data for all deliveries on randomly selected days over 3 years (2008–2011). Gestational was derived using delivery minus prepregnancy or first-trimester categorized as below, within, above Institute of Medicine (IOM) guidelines this retrospective cohort study. Maternal (primary repeat...