Eleven high mileage runners (HR) (108.0 +/- 4.5 km.wk-1), 9 moderate (MR) (54.2 3.7 km.wk-1) and 10 sedentary controls (SC) of similar age (28.3 1.5 yr) were studied to evaluate the effects volume endurance training on reproductive function in male runners. Levels reproductive, adrenal thyroid hormones measured during a 1-hr period serial blood sampling (q20 min) urinary excretion 24-hr luteinizing hormone (uLH) was determined two separate days. Semen exams sperm penetration standard...

Abstract In an ongoing project to evaluate natural compounds isolated from plants the Brazilian biodiversity as modulators of antibiotic resistance, kaempferol‐3‐ O ‐ β ‐d‐(6″‐E‐ p ‐coumaroyl) glucopyranoside (tiliroside), Herissantia tiubae (Malvaceae) was investigated using strain SA‐1199B Staphylococcus aureus , which overexpresses norA gene encoding NorA efflux protein extrudes hydrophilic fluorquinolones and some biocides, such benzalkonium chloride, cetrimide, acriflavine ethidium...

Leprosy is a chronic infectious disease caused by Mycobacterium leprae bacillus. It was considered to be an incurable for ages. Nowadays leprosy vanishing although we can meet it principally in the tropical zone countries. Brazil has second greatest number of cases around world with almost 30,000 new diagnosed 2005. The present work constitutes literature review on plant extracts and chemically defined molecules natural origin showing antileprotic activity. refers 11 plants, their families,...

In this study, we evaluate the technological, nutritional, and bioactivity effects on goat-milk yogurt of adding different concentrations xique-xique flour: 1.0% (XY1%) 2.0% (XY2%). The yogurts (stored under refrigeration) also contained Limosilactobacillus mucosae CNPC007 (an autochthonous strain). XY1% XY2% treatments presented greater intensity in terms color (yellow), luminosity (L*) during storage than control (CY). Up to 14th day storage, viscosity values as well. During any...

The phytochemical study of Sida rhombifolia L. (Malvaceae) led to the isolation through chromatographic techniques eleven secondary metabolites: sitosterol (1a) and stigmasterol (1b), sitosterol-3-O-b-D-glucopyranoside (2a) stigmasterol-3-O-b-D-glucopyranoside (2b), phaeophytin A (3), 173-ethoxypheophorbide (4), 132-hydroxy B (5), (6), 5,7-dihydroxy-4'-methoxyflavone (7), cryptolepinone (8) a salt cryptolepine (9). Their structures were identified by 1H- 13C-NMR using one- two-dimensional...

The prickly pear is a cactaceae that have chemical compounds act as natural antioxidants. In addition, the plant widely used in semiarid region it's considered very important forage for animal feed, especially dry season. objectives of this research were to characterize main classes phytochemicals, determine phenols content, flavonoids and anthocyanins evaluate antioxidant activity cultivars Opuntia Nopalea grown Pernambuco two collection periods (dry rainy). work crude ethanol extracts from...

Objectives To compare carotid intima-media thickness (cIMT) of children and adolescents with without HIV infection to determine associations among independent socio-demographic, clinical or cardiovascular variables cIMT in HIV-infected adolescents. Patients methods This is a matched case–control study comparing 83 healthy Clinical laboratorial parameters, echocardiogram were measured. Results The was higher individuals (median 480 μm; interquartile range 463–518 μm) compared controls (426...

From the aerial parts of Sidastrum micranthum (A. St.-Hil.) Fryxell (Malvaceae) were isolated m-methoxy-p-hydroxy-benzaldehyde, o-hydroxy-benzoic acid, acacetin, quercetin, 7,4′-Di-O-methylisoscutellarein, genkwanin and tiliroside. These compounds identified by data analyses spectroscopic methods. Although acacetin 7,4′-Di-O-methylisoscutellarein did not display relevant antibacterial activity (MIC = 256 µg/mL), they modulated antibiotics, i.e. in combination with antibiotics at 64 µg/mL (¼...

The species Waltheria viscosissima A.St.–Hil, Malvaceae, which is known as 'malva-branca', traditionally used in the Brazilian northeast for treatment of coughs. This research looks towards reporting isolation phytoconstituents W. viscosissima, well quantification its phenolics, total flavonoid content, and free radical scavenging potential, along with an evaluation larvicidal activity against Aedes aegypti larvae. Chromatographic techniques were to isolate compounds a structural elucidation...

Pavonia malacophylla (Link & Otto) Garcke (Malvaceae sensu lato), commonly known as “malva-rosa” or “malva-veludo”, is traditionally used to treat flu, cough, and heart pain. The crude ethanolic extract (CEE) of P. was obtained through maceration with ethanol, concentrated using a rotary evaporator, subjected vacuum liquid chromatography silica gel 60 the stationary phase. Hexane, ethyl acetate, methanol were mobile phases in increasing polarity gradients, yielding nine fractions....

Hypertension is a leading cause of death and disability globally, its prevalence continues to accelerate. The cardiovascular effects the flavonoid tiliroside have never been reported. In this work, using complementary <i>in vivo</i> vitro</i> approaches, we describe antihypertensive effect underlying mechanisms involved in reduction blood pressure. Tiliroside (1, 5 or 10 mg/kg) induced dose-dependent long-lasting decrease pressure conscious DOCA-salt hypertensive rats that was accompanied by...

Helicteres velutina K. Schum (Sterculiaceae), a member of Malvaceae sensu lato, is Brazilian endemic plant that has been used by the indigenous tribe Pankarare as an insect repellent. A previous study reported isolation terpenoids, flavonoids and pheophytins, in addition to larvicidal activity crude H. extracts derived from aerial components (leaves, branches/twigs, flowers). The present reports biomonitoring effects fractions isolated compounds against A. aegypti fourth instar larvae....

CHEMICAL CONSTITUENTS AND ANTIOXIDANT ACTIVITY OF Sida galheirensis Ulbr.(Malvaceae).The phytochemical investigation of led to the isolation 5,4'-dihydroxy-3,7,3´-trimethoxyflavone, 17 3 -ethoxyphaeoforbide, a rare natural product, 6,7-dimethoxycoumarin, ortho-hydroxybenzoic acid, sitosterol-3-O-β-D-glucopyranoside, stigmasterol-3-O-β-D-glucopyranoside, 5,7,4'-trihydroxyflavone, 5,7,3',4'-tetrahydroxyflavone, kaempferol-3-O-β-D-(6"-E-p-coumaroyl) glucopyranoside and luteolin...

Xique–xique (<italic>Pilosocereus gounellei</italic>) cladode juice at the dose of 5 mL kg⁻¹exerts an anti-inflammatory effect in colitis model.

This study aimed to evaluate the impact of adding Lacticaseibacillus casei (0.2 g/L) and xique-xique jam (10 g/100 g) goat milk yogurt during storage (1, 14, 28 days). The yogurts were characterized regarding sugar profiles, organic acids, volatile compounds, sensory attributes using Preferred Attribute Elicitation (PAE) methodology. Three formulations prepared: (CY) control (with sucrose), (XY) with jam, (PY) L. casei. Results showed that XY exhibited higher content, but acid compound...

The phytochemical study of Cordia exaltata Lam. (Boraginaceae) led to the isolation, through chromatographic techniques, nineteen secondary metabolites: 8,8'dimethyl-3,4,3',4'-dimethylenedioxy-7-oxo-2,7'cyclolignan (1), 8,8'-dimethyl-4,5-dimethoxy-3',4'-methylenodioxy-7-oxo-2,7'cyclolignan (2), sitosterol (3a), stigmasterol (3b), sitosterol-3-O-β-d-glucopyranoside (4a), stigmasterol-3-O-β-d-glucopyranoside (4b), phaeophytin A (5), 132-hydroxyphaeophytin (6), 173-ethoxypheophorbide (7),...

Helicteres velutina K. Schum (Sterculiaceae), commonly known in Brazil as 'pitó', is traditionally used by indigenous peoples insecticides and repellents. The present work reports on the phytoconstituents from aerial parts of H. evaluation larvicidal potential its extract. compounds were isolated using chromatographic techniques identified NMR, IR LC-HRMS. This study led to isolation a fatty acid, one aliphatic alcohol, four chlorophyll derivatives, steroid, triterpenes, lignan, flavonoids,...

Pilosocereus pachycladus F. Ritter, Cactaceae, popularly known as "facheiro", is used food and traditional medicine in Brazilian caatinga ecoregion. The plant to treat prostate inflammation urinary infection. present work reports the first secondary metabolites isolated from P. pachycladus. Therefore, compound 4-hydroxy-3,5-dimethoxy benzaldehyde (syringaldehyde) was evaluated modulator of Staphylococcus aureus pump efflux-mediated antibiotic resistance. isolation compounds performed using...

The phytochemical investigation of Bakeridesia pickelii Monteiro led to the isolation seven compounds: β-sitosterol, a mixture sitosteryl-3-O-β-D-glucopyranoside and stigmasteryl-3-O-β-D-glucopyranoside, vanillic acid, p-coumaric quercetin 3-O-β-Dglucopyranoside (isoquercitrin) kaempferol-3-O-β-D-(6"-E-p-coumaroyl) glucopyranoside (tiliroside), which was isolated as major component.Their structures were elucidated on basis spectroscopic data such IR, 1 H 13 C NMR, including twodimensional...