Yew Sen Yuen
A5078454310- Retinal Diseases and Treatments
- Ocular Diseases and Behçet’s Syndrome
- Retinal and Optic Conditions
- Retinal Imaging and Analysis
- Retinal Development and Disorders
- Cytomegalovirus and herpesvirus research
- Infectious Diseases and Tuberculosis
- Corneal Surgery and Treatments
- Glaucoma and retinal disorders
- Ophthalmology and Visual Health Research
- Viral Infections and Vectors
- Advanced Glycation End Products research
- Inflammatory Biomarkers in Disease Prognosis
- Systemic Lupus Erythematosus Research
- Vector-Borne Animal Diseases
- Pelvic floor disorders treatments
- Lipid metabolism and disorders
- Ocular Infections and Treatments
- Cancer Immunotherapy and Biomarkers
- Retinal and Macular Surgery
- Otitis Media and Relapsing Polychondritis
- Extracellular vesicles in disease
- Surgical Simulation and Training
- Adenosine and Purinergic Signaling
- MicroRNA in disease regulation
National University Hospital
2018-2024
Collaborative Group (United States)
2024
National University Health System
2020-2023
National University of Singapore
2020-2021
The utility of neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte (PLR) in predicting immune-related adverse events (irAEs) survival have not been well studied the context treatment with immune checkpoint inhibitors (ICIs). We performed a case-control study cancer patients who received at least one dose ICI tertiary hospital. examined NLR PLR irAE cases controls. Logistic Cox regression models were used to identify independent risk factors for irAEs, progression-free (PFS),...
Purpose . To identify systemic factors that may influence the response to anti-VEGF therapy in patients with diabetic macular edema (DME). Methods 35 undergoing injections for centre-involving DME were studied this prospective observational study. The primary outcome was change thickness one month after treatment, measured using spectral-domain optical coherence tomography (OCT). At baseline, information on various collected including glycosylated hemoglobin (HbA1c), serum VEGF levels, lipid...
<sec> <title>BACKGROUND</title> Mixed reality (MR) has the potential to transform delivery of medical education. With tools like HoloLens 2, educators can create immersive, interactive simulations that allow students practice and engage with real-world scenarios in a controlled environment. </sec> <title>OBJECTIVE</title> We postulate hybrid ophthalmology curriculum incorporates EyelearnMR (simulation application) traditional teaching is non-inferior teaching. compare learning outcomes...
(1) Background: Intravitreal anti-vascular endothelial growth factor (anti-VEGF) is an established treatment for center-involving diabetic macular edema (ci-DME). However, the clinical response heterogeneous. This study investigated miRNAs as a biomarker to predict anti-VEGF in DME. (2) Methods: Tear fluid, aqueous, and blood were collected from patients with treatment-naïve DME miRNA expression profiling quantitative polymerase chain reaction. Differentially expressed between good poor...
Importance This was the first study, to authors’ knowledge, statistically evaluate predictive accuracy of Collaborative Ocular Tuberculosis Study (COTS) calculator in guiding initiation antitubercular therapy (ATT) patients with clinically suspicious tubercular uveitis (TBU) an international cohort. Objective To a score 4 or greater on online COTS recommending ATT initiation. Design, Setting, and Participants study evaluation diagnostic test technology. Data input required for were extracted...
An international, expert led consensus initiative was set up by the Collaborative Ocular Tuberculosis Study (COTS) group to develop systematic, evidence, and experience-based recommendations for treatment of ocular TB using a modified Delphi technique process. In first round Delphi, identified clinical scenarios pertinent based on five phenotypes (anterior uveitis, intermediate choroiditis, retinal vasculitis, panuveitis). Using an interactive online questionnaires, guided background...
Background: Diabetic retinopathy (DR) screening using colour retinal photographs is cost-effective and time-efficient. In real-world clinical settings, DR severity frequently graded by individuals of different expertise levels. We aim to determine the agreement in grading between human graders varying an automated deep learning software (ADLS). Methods: Using International Clinical Disease Severity Scale, two hundred macula-centred fundus were specialists, ophthalmology residents, family...
An amendment to this paper has been published and can be accessed via a link at the top of paper.