A5019913976- Meningioma and schwannoma management
- Head and Neck Surgical Oncology
- Glioma Diagnosis and Treatment
- Bone Tumor Diagnosis and Treatments
- Craniofacial Disorders and Treatments
- Photodynamic Therapy Research Studies
- Nanoplatforms for cancer theranostics
- Spectroscopy Techniques in Biomedical and Chemical Research
- Facial Trauma and Fracture Management
- Neurofibromatosis and Schwannoma Cases
- Spectroscopy and Chemometric Analyses
- Optical Imaging and Spectroscopy Techniques
- Pituitary Gland Disorders and Treatments
- Cleft Lip and Palate Research
- Oral and Maxillofacial Pathology
- Advanced Neuroimaging Techniques and Applications
- Radiomics and Machine Learning in Medical Imaging
- Surgical Simulation and Training
- Spinal Fractures and Fixation Techniques
- Cancer Cells and Metastasis
- Sinusitis and nasal conditions
- Peripheral Nerve Disorders
- Photoacoustic and Ultrasonic Imaging
- Brain Metastases and Treatment
- Virus-based gene therapy research
Burdenko Neurosurgery Institute
2015-2024
Ministry of Health of the Russian Federation
2018-2019
Russian Children's Clinical Hospital
2018
Engelhardt Institute of Molecular Biology
2018
Centrum Gamma Knife
2017
The objective of this study is to analyze fluorescence sensitivity in diagnosis brain and spinal cord tumors. Material methods. authors conducted a multicenter retrospective analysis 653 cases 641 patients: 553 them had tumors, 88 Brain tumor resection was performed 523 patients, whom 484 were adults 39 children. analyzed series presented by 320 gliomas, 101 meningiomas 72 metastases. Stereotactic biopsy 20 patients endoscopic surgery 10 patients. In all mg/kg 5–Aminolaevulinic acid...
Introduction: Preoperative stereotactic radiosurgery (pre-SRS) is a recent advancement in the strategy for brain metastasis (BM) management, and available data demonstrate advantages of pre-SRS before postoperative radiation treatment, including lower rates local toxicity, leptomeningeal progression, high percentage control. The authors presented results patients with BM. Materials methods: Nineteen BM (11 female eight male) have been treated at N.N. Burdenko Medical Research Center...
Anatomy of the conduction tracts cerebral cortex has been studied for a long time. Invention diffusion tensor tractography renewed interest in this subject. The objectives work were to develop and improve protocols dissection association human brain with studying features their segmentation, topography, variability, compare obtained data MR data, prepare further clinical anatomical studies.We used 18 hemispheres (from 10 males 8 females; 9 left right hemispheres). mean age cadavers was 68...
Background Problem of closure skull base defects after removal craniobasal lesions, especially, craniofacial, is one the most challenging in neurosurgery. Persistent defect produces extremely high risk cerebrospinal fluid leaks and consecutive infectious complications. Local pedicled grafts are preferred material for plasty. In this study, authors present original technique using a buccal fat pad (BFP) graft. Anatomy functions BFP discussed details as well surgical illustrated by 2 case...
Nasal chondromesenchymal hamartoma (NCMH) is a rare benign tumor of the sinonasal tract in children with possible orbit and skull base involvement. We present 57th published observation this kind tumor. A 25-month-old female patient presented recurrent mass lesion tract. According to her history, she had feeding difficulties nasal obstruction since birth. She underwent partial resection at eight months age via transfacial approach local hospital. Due progression remnants, second surgery was...
The neurosurgery of intracranial tumors is often complicated by the difficulty distinguishing tumor center, infiltration area, and normal tissue. current standard for intraoperative navigation fluorescent diagnostics with a agent. This approach can be further enhanced measuring Raman spectrum tissue, which would provide additional information on its composition even in absence fluorescence. However, spectra to immediately helpful neurosurgeon, they must additionally processed. In this work,...
Radiation therapy induces double-stranded DNA breaks in tumor cells, which leads to their death. A fraction of glioblastoma cells repair such and reinitiate growth. It was necessary identify the relationship between high radiation doses proliferative activity evaluate contribution pathways, homologous recombination (HR), nonhomologous end joining (NHEJ) tumor-cell recovery. We demonstrated that GO1 culture derived from Patient G, who had previously been irradiated, proved be less sensitive...
Background Craniofacial chondroid tumors (CFCTs) constitute less than 1% of all intracranial mass lesions. No protocol for evaluation and management CFCTs is developed at the moment. Materials methods We analyzed 51 patients with operated on in Burdenko Neurosurgical Institute from 1980 until 2012, which included chondroma (15), chondroblastoma (3), chondromyxoid fibroma (11), chondrosarcoma (22). Age varied 2 to 76 years (mean, 40 y); series 23 women 28 men. All were divided into 4 groups:...
To report our experience with patient specific implants for one-step orbit reconstruction following hyperostotic SWM removal and to describe the evolution of technique through three surgical cases. Methods: Three cases are described. All given consecutively technique. Hyperostotic bone resection was facilitated by electromagnetic navigation cutting guides (templates). Based on a 3D model, silicone molds were made using CAD/CAM. Then PMMA implant fabricated from these molds. The adjusted...
Pineoblastoma is a rare malignant tumor of the central nervous system (CNS), which arises from parenchyma pineal gland. It characterized by aggressive clinical behavior and frequent metastases along craniospinal axis. Extraneural may occur due to surgical seeding cells beyond dura and/or hematogenous spread, ventriculoperitoneal shunting, or through Batson's plexus. To our knowledge, only six documented cases intraosseous pineoblastoma are described in literature. A 23-year-old female...
Ligation of the sphenopalatine and posterior nasal arteries is indicated for epistaxis as initial treatment or when conservative measures fail. In some patients, a transnasal approach its alternative transantral are not possible due to tumor filling corridor, pterygopalatine fossa, maxillary sinus. Aim this study was evaluate feasibility endoscopically assisted transoral ligation artery (MA). Six fresh cadaver specimens (12 sides), previously prepared with intravascular injections colored...
To study the peri-insular association tract anatomy and define permissible anatomical boundaries for resection of glial insular tumors with allowance surgical tracts.In an anatomic superior longitudinal fascicle system (SLF I, SLF II, III, arcuate fascicle), we used 12 specimens (6 left 6 right hemispheres) prepared according to Klingler's fiber dissection technique. confirm data, MR tractography (HARDI-CSD-tractography) conduction tracts, which was performed in two healthy volunteers.Except...
Transorbital neuroendoscopic surgery is a new skull base technique that uses the orbit as an artificial corridor to anterior and middle base. The space created between periorbita orbital walls by their additional resection gentle traction of contents. Skull structures are reached using cosmetic incisions. major advantages transorbital endoscopic approaches include variety, possibility combination, access central lateral lesions. aim this study was analyze primary results biopsy lesions,...
The article presents the literature data on structural variability and age-related features of midline anatomical structures anterior skull base (frontal sinus, ethmoid bone, parasellar region, medial orbital wall). This is area surgical interests neurosurgeons rhinosurgeons. study objective to analyze individual anatomy these structures. work illustrated with original images from authors' personal archive. eloquent in (structures within corridor, key landmarks, optic tract, internal carotid...
<b>Objectives</b> To evaluate the efficacy and safety of using a buccal fat pad for endoscopic skull base defect reconstruction. <b>Design</b> Descriptive anatomical study with an illustrative case presentation. <b>Setting</b> Anatomical was performed on 12 fresh human cadaver specimens injected arteries (24 sides). Internal carotid artery exposed in coronal plane via transpterygoid approach. The pedicled used <i>Participants</i>: head specimens; one patient operated proposed technique....