A5018272784- Synthesis and characterization of novel inorganic/organometallic compounds
- Organoboron and organosilicon chemistry
- Synthetic Organic Chemistry Methods
- Organometallic Complex Synthesis and Catalysis
- Cyclopropane Reaction Mechanisms
- Catalytic Alkyne Reactions
- Asymmetric Synthesis and Catalysis
- Catalytic Cross-Coupling Reactions
- Silicone and Siloxane Chemistry
- Organic Electronics and Photovoltaics
- Asymmetric Hydrogenation and Catalysis
- Crystallization and Solubility Studies
- Synthesis and Properties of Aromatic Compounds
- X-ray Diffraction in Crystallography
- Luminescence and Fluorescent Materials
- Organic Light-Emitting Diodes Research
- Molecular Junctions and Nanostructures
- Conducting polymers and applications
- Catalysis for Biomass Conversion
- Coordination Chemistry and Organometallics
- Membrane Separation and Gas Transport
- Catalytic C–H Functionalization Methods
- Organic Chemistry Cycloaddition Reactions
- Fluorine in Organic Chemistry
- Ferrocene Chemistry and Applications
Kurashiki University of Science and the Arts
2015-2024
Hiroshima University
1997-2016
Kurashiki Medical Center
2016
NTT (Japan)
2009
Kyushu University
2001-2008
Kyoto Institute of Technology
2006-2008
Tokai University
2007
A. N. Nesmeyanov Institute of Organoelement Compounds
2006
Kyungpook National University
2001-2005
Goethe University Frankfurt
2005
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTNickel-catalyzed reactions of 3,4-benzo-1,1,2,2-tetraethyl-1,2-disilacyclobutene with aromatic compoundsMitsuo Ishikawa, Shougo Okazaki, Akinobu Naka, and Hiromu SakamotoCite this: Organometallics 1992, 11, 12, 4135–4139Publication Date (Print):December 1, 1992Publication History Published online1 May 2002Published inissue 1 December 1992https://pubs.acs.org/doi/10.1021/om00060a033https://doi.org/10.1021/om00060a033research-articleACS...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPlatinum-catalyzed reactions of 3,4-benzo-1,1,2,2-tetraethyl-1,2-disilacyclobut-3-eneMitsuo Ishikawa, Akinobu Naka, and Joji OhshitaCite this: Organometallics 1993, 12, 4987–4992Publication Date (Print):December 1, 1993Publication History Published online1 May 2002Published inissue 1 December 1993https://pubs.acs.org/doi/10.1021/om00036a044https://doi.org/10.1021/om00036a044research-articleACS PublicationsRequest reuse permissionsArticle...
In this report, we summarize and analyze the 2024 Adaptyv EGFR protein design competition. Participants used computational ML methods of their choice to proteins bind EGFR, a key drug target that plays critical role in cell growth, differentiation, cancer development. Over 1800 designs were submitted competition across two rounds. Of these, 601 selected characterized for expression binding affinity with competitors both optimizing existing binders (achieving 1.21 nM) creating novel (de novo)...
Compound 1 reacts with TEMPO to yield the disiloxane 5 as major product. Stable germylenes 9 and 10 both reacted 1:2 adducts. The reaction of di-tert-butyl peroxide gave adduct 7 in addition 15% an unexpected trisilane, 8.
Reactions of stable silylenes 1 and 2 with a variety halogenated organic compounds have been studied. Depending on the nature halocarbon, products can be disilanes, LSiX−LSiR, or monosilanes, LSiXR, mixture both types products. Hexachloroethane reacts to give mainly dichlorodisilane, LSiX−LSiX. The experimental results are rationalized in terms several related free-radical chain mechanisms.
Variation of water ratio played an important role in the separation properties TTESPT membranes reverse osmosis applications.
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSilicon-Carbon Unsaturated Compounds. 50. Palladium-Catalyzed Reactions of 3,4-Benzo-1,1,2,2-tetraethyl-1,2-disilacyclobut-3-ene and Reinvestigation Its Thermal Dimerization ReactionAkinobu Naka, Masaki Hayashi, Shougo Okazaki, Mitsuo IshikawaCite this: Organometallics 1994, 13, 12, 4994–5001Publication Date (Print):December 1, 1994Publication History Published online1 May 2002Published inissue 1 December...
A novel pyrimidine-bridged organoalkoxysilane membrane was developed from 4,6-bis(3-(triethoxysilyl)-1-propoxy)-1,3-pyrimidine (BTPP) via a sol–gel process. Self-catalyzed and HCl-catalyzed BTPP sols with different water molar ratios were prepared for formation to tailor the microstructure of membranes. higher ratio led silica network improved porosity well-connected structure. Gas adsorption measurements indicated that xerogels tended show dense due an organic-rich hybrid structure, these...
Mobilities of charge carriers in thin films a series copolymers with repeat units consisting oligothiophenes bridged by Si atoms are measured over range oxidation stages order to study the influence π-conjugation length on mobility. The number thiophene ranges from five nine, polymers being designated accordingly PS5T PS9T. these polymer films, where intrachain hopping transport is restricted within each oligothienylene unit, constant low doping regions below 1%. As level increases,...
Abstract The synthesis and reactions of silacyclopropenes are summarized. Addition silylenes to acetylenes photochemical isomerization alkynyldisilanes known as two major routes for the silacyclopropenes. Silacyclopropenes had been thought be highly reactive difficult handle until first crystal structure a stable one was reported in 1980. Currently, however, it is commonly accepted that those molecules under ambient conditions when sufficiently bulky substituents introduced onto strained...
The cothermolysis of acetyl- and isopropionyltris(trimethylsilyl)silanes with (trimethylsilyl)acetylene afforded the ring-opened products derived from [2 + 2] cycloadducts, while a similar thermolysis pivaloyl- adamantoylpolysilanes produced cycloadducts products.
The cothermolysis of acetyl-, pivaloyl-, adamantoyl-, benzoyl-, and mesitoyltris(trimethylsilyl)silane (1−5) with acetone benzophenone at 140 °C was investigated. reaction the silene formed from 1 afforded no adducts but produced a dimer silene. thermally 2 reacted to give two cyclopropane derivatives (11) (12), silyl enol ether (9). Similar 3 derivative (14), along (13). generated 4 gave bicyclic compound 16 as sole product, while similar 5 2,2-dimethylmesityl(trimethylsiloxy)ethene....
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSilicon-Carbon Unsaturated Compounds. 51. Nickel-Catalyzed Reactions of 3,4-Benzo-1,1,2,2-tetraethyl-1,2-disilacyclobut-3-ene with Alkenes and DienesMitsuo Ishikawa, Shougo Okazaki, Akinobu Naka, Akitomo Tachibana, Susumu Kawauchi, Tokio YamabeCite this: Organometallics 1995, 14, 1, 114–120Publication Date (Print):January 1995Publication History Published online1 May 2002Published inissue 1 January 1995https://doi.org/10.1021/om00001a020RIGHTS &...
The thermolyses of adamantoyl-, pivaloyl-, and mesitoyltris(trimethylsilyl)silane (1a, 1b, 1c) with mesitylacetylene were investigated. cothermolysis 1a in a sealed glass tube at 160 °C for 24 h afforded the 1:3- 1:4-adduct, (1E,4Z)-5-adamantyl-2,4-dimesityl-1-[(mesitylethynyl)bis(trimethylsilyl)silyl]-5-(trimethylsiloxy)penta-1,4-diene (3a) (1E,4Z,6Z)-7-adamantyl-2,4,6-trimesityl-1-[(mesitylethynyl)bis(trimethylsilyl)silyl]-7-(trimethylsiloxy)hepta-1,4,6-triene (4a), 33% 48% yields....
Silole derivatives are attracting significant attention as new functional materials with excellent electronic and photophysical properties. Thus, the development of synthesis methods to afford such is highly desirable. Herein, pyridine-fused siloles under conditions Sonogashira coupling reaction described. The reactions 2-bromo-3-(pentamethyldisilanyl)pyridine (1) ethynylbenzene in presence PdCl2(PPh3)2-CuI a catalyst afforded corresponding (2a–2c) through intramolecular...
UV irradiation of poly[(tetraethyldisilanylene)(3,4-diethynylenesilole)] in the presence an excess Fe(CO)5 led to formation Fe(CO)3-coordinated silole units polymer backbone. The ratio and noncoordinated resulting was determined be 2:1 by 1H NMR spectrometry. Similar treatment poly[(tetramethyldisilanylene)(3,4-diethynylenesilole)] also afforded corresponding polymer. polymers with exhibit slightly red-shifted absorption bands, relative parent polymers. When doped FeCl3 vapor, became...
The reaction of 3,4-benzo-1,1,2,2-tetraethyl-1,2-disilacyclobut-3-ene (1) with bis(trimethylsilyl)acetylene in the presence a catalytic amount tetrakis(triethylphosphine)nickel(0) sealed glass tube at 150 °C for 24 h gave 5,6-benzo-1,1,4,4-tetraethyl-2,3-bis(trimethylsilyl)-1,4-disilacyclohexa-2,5-diene (2), 4,5-benzo-1,1,3,3-tetraethyl-2-[bis(trimethylsilyl)methylene]-1,3-disilacyclopent-4-ene (3), 5,5,6,6,11,11,12,12-octaethyl-5,6,11,12-tetrasilanaphthacene (4), and...
Heating silacyclobut-3-ene 2 at 250 °C afforded the trans-silacyclobut-3-ene 4, via silyl-substituted cycloprop-2-ene 3. The photolysis of 4 gave a 1:1 mixture and cis isomer 6, which was transformed into °C, quantitatively. Preliminary results theoretical treatment for isomerization 2' to 3' are described.
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTNickel-catalyzed reactions of 3,4-benzo-1,1,2,2-tetraethyl-1,2-disilacyclobut-3-ene with carbonyl compoundsMitsuo Ishikawa, Akinobu Naka, Shougo Okazaki, and Hiromu SakamotoCite this: Organometallics 1993, 12, 1, 87–90Publication Date (Print):January 1993Publication History Published online1 May 2002Published inissue 1 January 1993https://pubs.acs.org/doi/10.1021/om00025a018https://doi.org/10.1021/om00025a018research-articleACS PublicationsRequest...