- Plant Molecular Biology Research
- Traditional Chinese Medicine Analysis
- Renal Diseases and Glomerulopathies
- Cell Adhesion Molecules Research
- Pregnancy and Medication Impact
- Protease and Inhibitor Mechanisms
- Plant Reproductive Biology
- Aquaculture disease management and microbiota
- Plant-Microbe Interactions and Immunity
- Pharmacological Effects of Natural Compounds
- Diabetes and associated disorders
- Plant pathogens and resistance mechanisms
- Birth, Development, and Health
- Chromosomal and Genetic Variations
- Endoplasmic Reticulum Stress and Disease
- Systemic Sclerosis and Related Diseases
- Food Quality and Safety Studies
- Plant Genetic and Mutation Studies
- Ovarian cancer diagnosis and treatment
- Pregnancy and preeclampsia studies
- Anesthesia and Neurotoxicity Research
- Plant Gene Expression Analysis
- Erythrocyte Function and Pathophysiology
- Polysaccharides and Plant Cell Walls
- Aquaculture Nutrition and Growth
Guangzhou University of Chinese Medicine
2015-2024
Nanjing University
2021
Fujian Agriculture and Forestry University
2008-2020
Shanghai Normal University
2019
Shanghai Institute of Planned Parenthood Research
2015
Stanford University
2010
Albert Einstein College of Medicine
2005
Maternal cells play a critical role in ensuring the normal development of embryos, endosperms, and seeds. Mutations that disrupt maternal control embryogenesis seed are difficult to identify. Here, we completely deleted four MICRORNA167 (MIR167) genes Arabidopsis (Arabidopsis thaliana) using clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated protein9 (Cas9) genome-editing technology. We found plants with deletion MIR167A phenocopied overexpressing...
The timely release of mature pollen following anther dehiscence is essential for reproduction in flowering plants. AUXIN RESPONSE FACTOR17 (ARF17) plays a crucial role wall pattern formation, tapetum development, and auxin signal transduction anthers. Here, we showed that ARF17 also involved dehiscence. Arabidopsis (
Abstract Engagement of TCRs induces actin rearrangements, which are critical for T cell activation. responses require new polymerization, but the significance higher-order structures, such as microfilament bundles, is unknown. To determine role actin-bundling protein leukocyte-plastin (L-plastin; LPL) in this process, cells from LPL−/− mice were studied. markedly defective TCR-mediated cytokine production and proliferation. also spread inefficiently on surfaces with immobilized TCR ligands...
Xuebijing injection (XBJ) is widely used to treat nephrotic syndrome (NS) in clinic, but its bioactive components and therapeutic mechanism are still unclear. In this study, the of XBJ were determined by ultra-performance liquid chromatography quadrupole time-of-flight tandem mass spectrometry (UPLC-Q-TOF/MS). The effect on NS was evaluated BALB/c mice induced adriamycin (ADR, 10 mg/kg) via a single tail vein. protective podocytes demonstrated using mouse (MPC-5) lipopolysaccharide (LPS, 4...
The flowers of angiosperm species typically contain specialized conical cells. Although substantial progress has been achieved regarding the mechanisms underlying flower development, little is known about how petal cells achieve final shape. Here, we use 8-hydroxypyrene-1,3,6-trisulfonic acid trisodium salt (HPTS) as a fluorescent pH indicator for analyzing apoplastic in Arabidopsis and show that normal cell expansion requires auxin signaling changes. By combining imaging analysis genetic...
A feeding trial was conducted to estimate the quantitative requirement of dietary methionine in largemouth bass[initial body weight (37.88±0.40) g].Six isonitrogenous and isoenergetic diets( D1-D6) were formulated contain 44.39% crude protein,0.30% cystine,19.81 kJ/g gross energy using plant protein crystalline amino acids as primary source simulate indispensable acid profile bass muscle except for under investigation.Six graded levels methionine( 0.61% ,0.83% ,0.98% ,1.21% ,1.42% ,and 1.59%...
Abstract We have previously observed that replication and nuclear location of the murine Igh locus are developmentally regulated during B cell differentiation. In non-B, B, plasma cells, sequences near 3′ end replicate early in S while upstream Vh late S, is located periphery. fact, MEL non-B a 500-kb segment containing Igh-C flanking occurs progressively later throughout by to 5′ unidirectional fork movement. contrast, pro- pre-B entire 3-Mb away from periphery replicates forks progressing...
High dose of Zishen Yutai pill (ZYP) showed mild maternal toxicity in rat (24 g kg<sup>−1</sup> d<sup>−1</sup>, 96× clinical dose) and no reproductive rabbit (6 24× dose). ZYP could be safely used at the during pregnancy.
Abstract Sclerotinia sclerotiorum causes severe stem rot disease in many crops. Little is known about the genetic mechanism of pathogenesis, making it difficult to breed new, disease‐resistant crop varieties. Here, we report a screen for Arabidopsis mutants with enhanced resistance S. through functional genomics approach. First, an activation‐tagged library thaliana Col‐4 was generated, followed by screening more than 50 000 T1 lines inoculating detached leaves. Second, were further...