A5014827478- Gold and Silver Nanoparticles Synthesis and Applications
- Nanocluster Synthesis and Applications
- Advanced biosensing and bioanalysis techniques
- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Nanoplatforms for cancer theranostics
- Adenosine and Purinergic Signaling
- Biosensors and Analytical Detection
- Protein Interaction Studies and Fluorescence Analysis
- Spectroscopy Techniques in Biomedical and Chemical Research
- Advanced Nanomaterials in Catalysis
- Crystallography and molecular interactions
- Nanomaterials for catalytic reactions
- Peptidase Inhibition and Analysis
- Alzheimer's disease research and treatments
- Medical Imaging and Analysis
- Quantum Dots Synthesis And Properties
- Polymer composites and self-healing
- Nanoparticle-Based Drug Delivery
- Structural and Chemical Analysis of Organic and Inorganic Compounds
- Photoacoustic and Ultrasonic Imaging
- Photonic and Optical Devices
- Laser-Ablation Synthesis of Nanoparticles
- Gastroesophageal reflux and treatments
- Connective tissue disorders research
Università di Camerino
2023-2025
St Petersburg University
2019-2024
Natural and renewable sources of calcium carbonate (CaCO3), also referred to as "biogenic" sources, are being increasingly investigated, they generated from a number waste in particular those the food industry. The first obvious application biogenic is production cement, where CaCO3 represents raw material for clinker. Overtime, other more added-value applications have been developed filling modification properties polymer composites, or development biomaterials, it possible transform into...
Adenosine, a pervasive signaling molecule mediated by its interaction with G-protein-coupled receptor subtypes, especially the A2A adenosine (A2AAR), plays crucial role in cancer treatment. Recently, A2AAR targeting analogs have been proposed as potential therapeutic target for However, molecules and their mode of action inhibiting glioblastoma cell progression remain unknown. We synthesized six derivatives substituted at 9-, 2- and/or N6- 8- positions, anti-proliferative efficacy against...
Anisotropic gold nanoparticles have been recognized as promising agents for medical diagnostics and cancer therapy due to their wide functionality, photothermal effect, ability optical signal amplification in the near-infrared range. In this work, a simple rapid method preparation of bone-shaped coated with dye-impregnated silica shell an aminated surface is proposed. The possibility further functionalization nanostructures delivery vector using folic acid example demonstrated. average size...
We have investigated the surface-enhanced resonance Raman spectroscopy (SERRS) for 4,4′-diaminotolane absorbed on silver experimentally and theoretically. Experimental observation shows greatly enhanced bg symmetric modes ν26 ν27, which are silent in normal SERS gold. The dependence of (SERS) spectra five excitation lines has also been registered classified single bands into three profiles referring to different contributions resonant transitions. Theoretical calculations based...
The report describes the synthesis of core-shell noble metal anisotropic nanoparticles modified with cyanine-class fluorophores and stilbene-based Raman reporters. In perspective, it may be used for optical diagnostics therapeutic hyperthermia.
Синдром Уилки, или синдром верхней брыжеечной артерии (СВБА) — относительно редкое состояние, обусловленное аномальным отхождением от брюшного отдела аорты из-за исчезновения жировой ткани, которая обеспечивает стабильность угла между двумя крупными артериальными сосудами, и, соответственно, сдавливанием двенадцатиперстной кишки с последующим нарушением пассажа. Развитие синдрома учитывая данные литературы и собственный опыт, всегда вторично. Особенностью нашего клинического случая Уилки у...
Введение. Частота болезни Гиршпрунга (БГ) у пациентов с синдромом Дауна (СД) значительно выше, чем в популяции, и составляет от 2,76 до 16%. В статье рассматриваются особенности течения заболевания БГ сочетании СД, факторы риска развития осложнений пути их профилактики лечения. Цель представленной работы заключалась анализе распространенности детей Дауна, а также выявлении факторов осложнений, выработке стратегий лечения данной группы пациентов. Материалы методы. За период 2016 по 2024 г....
Star-shaped gold nanoparticles modified with cyanine 5.5 derivatives were studied as optical tags for bioimaging by surface-enhanced Raman scattering (SERS). Obtained showed a plasmon resonance band at 640 nm in the absorption spectra which ensures them maximum efficiency when excited red lasers. SERS measurements carried out particles solution phase and after incubation PANC-1 cell line. The of solutions revealed characteristic signal amino derivative range 100-1000 cm -1 , where there is...
In this paper, the DFT calculations for three stilbene derivatives, of 4-aminostilbene, 4,4'-diaminostilbene and 4-amino- 4'-(N,N-diethylamino)stilbene, are proposed enabling to assign SERS spectra reliably, including in «hot spots» conditions. The choice best model is made based on more than 50 molecule*Agn clusters. We studied, how cluster size (4, 6 14 silver atoms), charge (positive localized, non-localized neutral) solvent accounting affect results calculation. obtained theoretical data...
Currently, the number of patients with neurodegenerative pathologies is estimated at over one million, consequences also on economic level. Several factors contribute to their development, including overexpression A2A adenosine receptors (A2AAR) in microglial cells and up-regulation post-translational alterations some casein kinases (CK), among them, CK-1δ. The aim work was study activity A2AAR CK1δ neurodegeneration using in-house synthesized A2A/CK1δ dual anta-inhibitors evaluate...