A5048639574- Inhalation and Respiratory Drug Delivery
- Advanced Drug Delivery Systems
- Advancements in Transdermal Drug Delivery
- Nanoparticle-Based Drug Delivery
- RNA Interference and Gene Delivery
- Drug Solubulity and Delivery Systems
- Lipid Membrane Structure and Behavior
- Clay minerals and soil interactions
- Microencapsulation and Drying Processes
- Contact Dermatitis and Allergies
- Proteoglycans and glycosaminoglycans research
- Cancer-related molecular mechanisms research
- Neonatal Respiratory Health Research
- Advanced biosensing and bioanalysis techniques
- Microbial Metabolites in Food Biotechnology
- Cannabis and Cannabinoid Research
- RNA modifications and cancer
- Therapeutic Uses of Natural Elements
- Skin Protection and Aging
- Electrospun Nanofibers in Biomedical Applications
- Proteins in Food Systems
- Intestinal and Peritoneal Adhesions
- Adsorption, diffusion, and thermodynamic properties of materials
- Surfactants and Colloidal Systems
- Food Chemistry and Fat Analysis
University of Modena and Reggio Emilia
2016-2025
The active targeting to alveolar macrophages (AM) is an attractive strategy improve the therapeutic efficacy of 'old' drugs currently used in clinical practice for treatment pulmonary tuberculosis. Previous studies highlighted ability respirable solid lipid nanoparticle assemblies (SLNas), loaded with rifampicin (RIF) and functionalized a novel synthesized mannose-based surfactant (MS), both alone blend sodium taurocholate, efficiently target AM via mannose receptor-mediated mechanism. Here,...
Recently, solid lipid nanoparticles (SLNs) have attracted increasing attention owing to their potential as an oral delivery system, promoting intestinal absorption in the lymphatic circulation which plays a role disseminating metastatic cancer cells and infectious agents throughout body. SLN features can be exploited for of theranostics. Therefore, aim this work was design characterise self-assembled (SALNs) encapsulate stabilise iron oxide non-covalently coated with heparin (Fe@hepa) model...
The mimicking of physiological conditions is crucial for the success accurate in vitro studies. For inhaled nanoparticles, which are designed being deposited on alveolar epithelium and taken up by macrophages, it relevant to investigate interactions with pulmonary surfactant lining alveoli. As a matter fact, formation lipid corona layer around nanoparticles could modulate cell internalization fate transported drugs. Based this concept, present research focused between Solid Lipid...
There is a pressing need for efficacious therapies in the field of respiratory diseases and infections. Lipid nanocarriers, administered through aerosols, represent promising tool maximizing therapeutic concentration targeted cells minimizing systemic exposure. However, this approach requires application efficient safe nanomaterials. Palmitoylethanolamide (PEA), an endocannabinoid-like endogenous lipid, plays crucial role providing protective mechanisms during inflammation, making it...