A series of polyethylene glycol (PEG)-functionalized basic ionic liquids (ILs) were developed for efficient CO2 conversion into organic carbonates under mild conditions. In particular, BrTBDPEG150TBDBr was proven to be a highly and recyclable catalyst the synthesis cyclic without utilization any solvents or additives. This is presumably due activation epoxide assisted by hydrogen bonding ether linkage in PEG backbone through formation carbamate species with secondary amino group IL cation on...

Reactions involving allenyl ion intermediates have been widely applied in the synthesis of functionalized allenes, but reactions radicals less studied and limited successful examples realized mainly by transition metal catalysis. We herein demonstrate generation N-heterocyclic carbene (NHC) organocatalysis their applications three-component radical relay 1,4-alkylcarbonylation 1,3-enynes without participation. This strategy could accommodate a collection different alkyl precursors such as...

The recent advances in N -heterocyclic carbene (NHC)-catalyzed generation of azolium dienolates from different precursors and their synthetic applications for the construction various valuable molecules are summarized comprehensively this review.

Readily available iron compounds were found to be active catalysts for the selective oxidation of sulfide sulfoxide with molecular oxygen as oxidant in polyethylene glycol (PEG). As an indispensable component, PEG had a great promotive effect on reaction. Notably, high conversion (>99%) along excellent chemo-selectivity up 94% could attained by using Fe(acac)2 catalyst at 100 °C. This methodology was proved applicable transformation various aromatic and aliphatic sulfides into corresponding...

Reported here is a novel photoinduced strategy for the borylation of aryl sulfonium salts using bis(pinacolato)diboron as boron source. This method exploits redox-neutral sulfoniums to gain access radicals via C–S bond activation upon photoexcitation under transition-metal-free conditions. Therefore, it grants diverse arylboronate esters with good performance from easily available accompanied by mild conditions, operational simplicity, and easy scalability.

Abstract Palladium‐catalyzed allylic alkylation of nonstabilized carbon nucleophiles is difficult and remains a major challenge. Reported here highly chemo‐ regioselective direct palladium‐catalyzed C‐allylation hydrazones, generated from carbonyls, as source umpolung unstabilized alkyl carbanions surrogates organometallic reagents. Contrary to classical allylation techniques, this reaction utilizes hydrazones prepared not only aryl aldehydes but also ketones renewable feedstocks. This...

An unprecedented N-heterocyclic carbene and magnesium cocatalyzed three-component acylcyanoalkylation of alkenes with cycloketone oxime esters aldehydes is presented. This method displayed good scope generality, providing a transition-metal- photoredox-free pathway to access various multifunctionalized aliphatic keto nitrile structures under mild reaction conditions. Moreover, this strategy supposed follow radical relay mechanism via single electron transfer event Mg/matched Breslow...

The first catalytic asymmetric construction of axially chiral 4-aryl α-carboline skeletons has been accomplished through an N-heterocyclic carbene (NHC)-catalyzed atroposelective formal [3 + 3] annulation 4-nitrophenyl 3-arylpropiolates with 2-sulfonamidoindolines. synthetic utility the title compounds demonstrated by diverse late-stage structural modifications. Density functional theory calculations were also conducted to illuminate key factors for controlling origin enantioselectivity....

An N-heterocyclic carbene (NHC)-catalyzed facile assembly of α-sulfonyl ketones has been successfully developed through a radical-mediated sulfonyl methylation readily available aldehydes. This protocol involves the effective single-electron transfer reduction α-iodosulfones by NHC-bound Breslow intermediates, thus allowing subsequent radical-radical coupling to afford target compounds. Moreover, catalytic system was found be equally for difunctionalization styrenes and 1,3-enynes via...

Abstract N ‐Heterocyclic carbene (NHC) catalyzed radical‐radical reactions have been proven to be powerful strategies for assembling ketyl‐containing compounds via single electron transfer (SET) pathway under either thermal conditions or photoredox conditions. In this context, acylation of alkenes radical relay NHC‐organocatalysis has also opened a new window the difunctionalization construct valuable molecules in organic synthesis. review, advances and progress were summarized according...

A nickel-catalyzed cross-coupling to construct the C(sp2)–C(sp3) bond was developed from two sustainable biomass-based feedstocks: phenol derivatives with umpolung aldehydes. This strategy features in situ generation of moisture/air-stable hydrazones naturally abundant aldehydes, which act as alkyl nucleophiles under catalysis couple readily available derivatives. The avoidance using both halides electrophiles and organometallic or organoboron reagents (also derived halides) makes this...

A novel surface enhanced Raman scattering (SERS) detection method is fabricated for miRNA based on a smart multifunctional probe dual cyclical nucleic acid strand-displacement polymerization (CNDP).

As an abundant, nontoxic, nonflammable, easily available, and renewable carbon resource, dioxide is very attractive as environmentally friendly feedstock for making commodity chemicals, fuels, materials. Owing to its kinetic thermodynamic stability, significant efforts have been directed towards constructing C-C, C-O C-N bond on the basis of CO2 activation through molecular catalysis. Development catalytic methodologies chemical transformation into useful compounds paramount importance from...

An easily prepared Fe(III)-derived Lewis acid ionic liquid ([C4mim][FeCl4]), being comprised of 1-butyl-3-methyl imidazolium cation and tetrachloroferrate anion, was found to be an efficient, recyclable catalyst for benzylation various arenes/heteroarenes into the diarylmethanes derivatives under mild reaction conditions without utilization additional organic solvent. Interestingly, acidity [C4mim][FeCl4] could account its catalytic activity in promoting acid-catalyzed alkylation. Notably,...

An iron(III)-catalyzed three-component coupling reaction of alkynes, CH(2)Cl(2) and amines was developed for facile synthesis propargylamines. Preliminary mechanism investigation using in situ FT-IR reveals that the crucial Fe-acetylide intermediate could be formed through C-H bond activation alkynes thanks to cooperative effect FeCl(3) 1,1,3,3-tetramethylguanidine.

Rh(III)-catalyzed efficient C-H alkynylation of azomethine imines with alkynylated hypervalent iodine is developed under mild conditions. A broad scope and alkyne substrates established. The acts as a masked aldehyde circumvents its poor directing effect.

For an optimal design of a surface-mounted permanent magnet synchronous motor (SPMSM), many objective functions should be considered. The classical optimization methods, which have been habitually designed based on magnetic circuit law or finite element analysis (FEA), inaccuracy calculation time problems when solving the multi-objective problems. To address these problems, multi-independent -population genetic algorithm (MGA) combined with subdomain (SD) model are proposed to improve...

N -Heterocyclic carbene-catalyzed difluorocyclopropanation of alkenes with aldehydes and CF 2 Br for a facile efficacious synthesis new class functionalized gem -difluorocyclopropanes bearing acyl groups was developed.

Earth-abundant and well-defined iron complexes are found to be cheap effective catalysts for a series of "umpolung" nucleophilic additions hydrazones. The new catalytic system not only maintains the broad substrate scope an earlier expensive ruthenium but also attains chemoselectivity different kinds carbonyl groups. Furthermore, catalyst enables this reaction at ambient temperature.

The synergistic combination of N-heterocyclic carbene organocatalysis and transition-metal catalysis for a formal [3 + 2] annulation between 3-substituted but-2-enoates 1-tosyl-2-vinylaziridine was developed. This cooperative strategy provides facile efficient access to various functionalized (E)-3-ethylidene-4-vinylpyrrolidin-2-ones in regioselective stereoselective manner. preliminary asymmetric studies were also performed, which indicated potential enantioselective vinyl enolate...