Н Н Крылов

ORCID: 0000-0003-0078-9171
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About
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Research Areas
  • Anorectal Disease Treatments and Outcomes
  • Colorectal Cancer Surgical Treatments
  • Diverticular Disease and Complications
  • Colorectal and Anal Carcinomas
  • Medical History and Innovations
  • Pelvic floor disorders treatments
  • Esophageal and GI Pathology
  • Neuroblastoma Research and Treatments
  • Pancreatic function and diabetes
  • Medicine and Dermatology Studies History
  • Hidradenitis Suppurativa and Treatments
  • Gastric Cancer Management and Outcomes
  • Helicobacter pylori-related gastroenterology studies
  • Lung Cancer Research Studies
  • Neuroendocrine Tumor Research Advances
  • Eosinophilic Esophagitis
  • Medical and Agricultural Research Studies
  • Abdominal Trauma and Injuries
  • Healthcare Systems and Public Health
  • Trauma, Hemostasis, Coagulopathy, Resuscitation
  • History of Medical Practice
  • Gastrointestinal Tumor Research and Treatment
  • Cardiac, Anesthesia and Surgical Outcomes
  • Erythrocyte Function and Pathophysiology
  • Sociopolitical Dynamics in Russia

Sechenov University
2016-2025

During the 19th century, scope of blood transfusion was significantly expanded. Along with obstetric practice, hemotransfusion has been actively used in fight against acute loss combat and traumatic injuries. New broad opportunities for development method were obtained during numerous military campaigns XIX accompanied by an increase destructive power firearms number wounded who died from massive bleeding on battlefield. The article examines how high hopes introduction among means helping...

10.17116/hirurgia2025021130 article EN Pirogov Russian Journal of Surgery 2025-02-07

The article highlights the basic experiments of predecessors, which served as an impetus for clinical development transfusiology in surgery three main directions: hemotransfusion, intravenous transfusion aqueous solutions salts and glucose, well parenteral administration natural milk. immediate results each options are shown, dangers complications that accompanied accumulation experience described. problems could be solved only with further science formulated.

10.17116/hirurgia2025031156 article EN Pirogov Russian Journal of Surgery 2025-03-19

The prerequisite for the development of Russian psychophysiology was need to regulate activities military personnel related specifics their work. purpose is highlight formation and professional psychophysiological selection in Russia, reflecting role scientists at S.M. Kirov Military Medical Academy this process. Materials methods. General scientific (analysis, synthesis, generalization), special historical (historical-genetic, historical-systemic) methods are used. Results. work from made a...

10.47470/0044-197x-2025-69-2-187-192 article EN Health Care of the Russian Federation 2025-04-30

Статья посвящена истории появления солевых растворов для внутривенного введения в качестве кровезаменителя. Подчеркнут российский приоритет этой области благодаря опытам сотрудников «Заведения искусственных минеральных вод на Остоженке» химика R. Hermann и врача F. Jaehnichen 1830 г., работавших под руководством Х. И. Лодера.

10.30906/0869-2092-2024-87-8-30-37 article RU Экспериментальная и клиническая фармакология 2024-09-09

To compare laparoscopic and open closure of perforated peptic ulcer (PPU).The study included 153 patients who underwent PPU suturing. 78 (laparoscopic group) suturing via upper midline laparotomy was performed in 75 cases (open group). Surgery time, postoperative pain severity, time analgesics intake, complications, hospital-stay cosmetic effect were compared.Laparoscopic may be effective accessible experienced endoscopic surgeon. It significantly reduces need for analgesics, incidence...

10.17116/hirurgia2017245-50 article RU Pirogov Russian Journal of Surgery 2017-01-01

Gastrointestinal neuroendocrine tumors are rare neoplasms. Currently, incidence of gastric (gNETs) is being significantly increased. There 3 groups gNETs: types I, II and III. Each type has important features regarding clinical picture, prognosis treatment strategy. Type I the most common (70-80%) associated with chronic atrophic gastritis including autoimmune Helicobacter gastritis. (5-6%) multiple endocrine neoplasia Zollinger-Ellison syndrome (MEN - ZES). Both characterized by...

10.17116/hirurgia2019121111 article RU Pirogov Russian Journal of Surgery 2019-01-01

to define the correlation between Mannheim peritonitis index scores and outcomes of different radical palliative interventions for perforative duodenal ulcer.Treatment 386 patients with ulcer is presented. Different surgical techniques were analyzed including stomach resection, various methods vagotomy with/without drainage, suturing ulcerative edges excision in <21, 21-29 over 29. Clavien-Dindo classification was used analyze postoperative complications.In 64.3% cases mortality caused by...

10.17116/hirurgia2016718-22 article RU Pirogov Russian Journal of Surgery 2016-01-01

To compare oncologic efficiency of intersphincteric resections and extralevator abdominoperineal excisions in surgical treatment low rectal cancer.Between 2006 2015 Department colorectal pelvic floor surgery (Russian scientific center n.a. acad. B.V. Petrovsky) Clinic Colorectal Minimally invasive (Sechenov First Moscow State Medical University) 40 consecutive patients underwent resection (ISR) 31 excision (EAPE). All had cancer staged I-III within 5 cm from the anal verge.Circular margin >1...

10.17116/hirurgia2017461-68 article RU Pirogov Russian Journal of Surgery 2017-01-01

To compare different clinical and morphometric features of patients undergoing TPAIT for prediction postoperative outcomes.A retrospective review enrolled who underwent the period from January 2007 to October 2017. Morphometric parameters were analyzed using preoperative CT scans grouped examine association these characteristics with morbidity. Sarcopenia was defined as presence a TPA in lowest sex-specific quartile. The impact sarcopenia on pancreatic islet features, perioperative blood...

10.17116/hirurgia202005112 article RU Pirogov Russian Journal of Surgery 2020-01-01

The article is devoted to historiography of perfluorocarbons, as well discoverers perftorane and their discoveries. There would be no national priority in transfusiology without these Perftorane the only one world series perfluorocarbon emulsion drugs that has passed all phases clinical trials. been used medicine for 30 years.

10.17116/hirurgia2024021111 article EN Pirogov Russian Journal of Surgery 2024-01-01

The article analyses research activities of the discoverers "Russian narcosis" from Military Medical Academy St. Petersburg: head Department Pharmacology N. P. Kravkov, Hospital Surgery S. Fedorov and his resident A. Eremich. They for first time in world developed ideas comprehensive experimental substantiation then safe clinical administration preparation "hedonal" to achieve stage general anesthesia implementation long-term traumatic operations. scientific works Russian indicated...

10.32687/0869-866x-2024-32-2-286-290 article EN Problems of Social Hygiene Public Health and History of Medicine 2024-03-01

The article is devoted to the description of formation, goals and objectives medical archaeoparasitology, research methods used by it, relationship with other sciences this field, importance its results for understanding evolution parasitic diseases under influence population migration, host change, climate change. Key words: paleoparasitology, pathoecology, history medicine

10.33092/0025-8326mp2024.1.43-49 article EN Medical Parasitology and Parasitic Diseases 2024-01-01

Common symbol of medicine is the snake entwining stick or “the staff Asclepius”. This image presented on emblem (coat arms) and flag World Health Organization. The authors explain as a reflection ancient method extraction guinea worm. Key words: dracunculosis, worm,

10.33092/0025-8326mp2024.1.50-54 article EN Medical Parasitology and Parasitic Diseases 2024-01-01

Статья посвящена сравнительной оценке свойств и клинических характеристик зарубежных кровозаменителей с газотранспортной функцией, созданных на основе перфторуглеродов, отечественного препарата «Перфторан». Для этого рассмотрены результаты предварительных исследований флукозола DA, оксигента Oxygent, оксицита Oxycyte, OxyFluor эмульсии № II. Представлены доказательства достижения мирового приоритета для в этой области.

10.30906/0869-2092-2024-87-6-34-38 article RU Экспериментальная и клиническая фармакология 2024-06-30

The article considers evaluation of works colleagues and contemporaries N. P. Kravkov, the creator "Russian narcosis" with hedonal. hidden explicit, objective subjective factors that prevented spreading application discovery Russian scientists, both in Russia abroad, are established. dependence self-esteem surgeons XIX - early XX centuries on recognition their scientific efforts Germany is emphasized.

10.32687/0869-866x-2024-32-3-480-483 article EN Problems of Social Hygiene Public Health and History of Medicine 2024-05-01

Статья посвящена истории внедрения безболезненной хирургии в России, у истоков которой стояли выдающиеся российские ученые — А. М. Филомафитский, Ф. И. Иноземцев и Н. Пирогов. Сформулированы доказательства существования российских приоритетов становления экспериментальной, клинической фармакологии анестезиологии.

10.30906/0869-2092-2024-87-7-39-46 article RU Экспериментальная и клиническая фармакология 2024-07-30

Требования к искусству хирурга ХХI века можно сформулировать тремя основными условиями: умение правильно обращаться с видео(робот)-ассистированной техникой, безопасно применять разнообразные электрохирургические инструменты и вместо ручного шва чаще использовать сшивающие аппараты. Одна из областей современной хирургии, в которойуже невозможно представить использование классического шва, — это низкий колоректальный анастомоз помощью специального сшивающего аппарата хирургии рака прямой...

10.56871/mhco.2024.51.82.010 article RU cc-by Medicine and health care organization 2024-03-11

Статья посвящена историю возникновения взглядов о нутрициологии и инфузионной терапии. На основе публикаций девятнадцатого века показана попытка замены алло- ксено-гемотрансфузий внутривенным введением молока с лечебной целью. После этого была выявлена гибель пациентов непосредственно после операции частые побочные эффекты, что можно объяснить анафилактической реакцией. Установлено, как широкий спектр показаний к этой операции, в течение полувека заканчивается ее полным забвением...

10.34921/amj.2024.4.030 article RU Azerbajdžanskij medicinskij žurnal 2024-12-25

To compare the immediate and long-term results of surgical treatment hemorrhoidal disease (GD) stage II-III using two methods identification arteries (HA) with their subsequent ligation mucopexy.A prospective, randomized, controlled, single-center study was conducted to evaluate effectiveness HA without Doppler navigation. The included 120 patients: group A - Doppler-guided (n=60) B ultrasound (n=60).GD II found in 27 patients 30 (p=0.4). Mean number ligated 3.36, 2.83 (p=0.062). mucopexy...

10.17116/hirurgia202112149 article RU Pirogov Russian Journal of Surgery 2021-01-01

To analyze the outcomes of single-port laparoscopic cholecystectomy.Early and long-term postoperative period has been analyzed in 240 patients who underwent cholecystectomy (LCE) including 120 cases technique four-port technique. Both groups were compared surgical time, pain syndrome severity (visual analog scale), need for analgesics, complications, hospital-stay, daily activity recovery return to physical work, patients' satisfaction results their aesthetic effect.It was revealed that LCE...

10.17116/hirurgia20161119-24 article RU Pirogov Russian Journal of Surgery 2016-01-01

Decision-making process is often complex, responsible and not always reflected in surgical protocol. Some surgeons usually prefer standard finishing of procedure; others talk about individual approach but they have some preferences; the third ones analyze all possible perioperative factors (pre- intraoperative data) seek to justify differentiated approach. aspects these processes are discussed this report.Считают, что на 75% результат лечения в сложных интраоперационных ситуациях обусловлен...

10.17116/hirurgia201810187 article RU Pirogov Russian Journal of Surgery 2018-01-01

Literature data devoted to transplantation of Langerhans cells have been analyzed. The main stages, indications, dissection islets, immunosuppressive therapy, complications and the latest clinical trials were discussed.Диабет 1-го типа (СД1) возникает в результате аутоиммунного повреждения островков Лангерганса поджелудочной железы, сопровождаемого аутоиммунным разрушением β-клеток. В настоящее время во всем мире наблюдается рост числа пациентов, страдающих СД1. представленном обзоре...

10.17116/hirurgia201811180 article RU Pirogov Russian Journal of Surgery 2018-01-01
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